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In histopathological image analysis, feature extraction for classification is a challenging task due to the diversity of histology features suitable for each problem as well as presence of rich geometrical structures. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2016-03-30 Tiep Huu Vu , Hojjat Seyed Mousavi , Vishal Monga , Arvind UK Rao , Ganesh Rao

Background and objective: Sharing of medical data is required to enable the cross-agency flow of healthcare information and construct high-accuracy computer-aided diagnosis systems. However, the large sizes of medical datasets, the massive…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Guang Li , Ren Togo , Takahiro Ogawa , Miki Haseyama

Generating high-quality labeled image datasets is crucial for training accurate and robust machine learning models in the field of computer vision. However, the process of manually labeling real images is often time-consuming and costly. To…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Michael Shenoda , Edward Kim

In medical imaging, developing generalized segmentation models that can handle multiple organs and lesions is crucial. However, the scarcity of fully annotated datasets and strict privacy regulations present significant barriers to data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Pochuan Wang , Chen Shen , Masahiro Oda , Chiou-Shann Fuh , Kensaku Mori , Weichung Wang , Holger R. Roth

Medical image segmentation has been significantly advanced with the rapid development of deep learning (DL) techniques. Existing DL-based segmentation models are typically discriminative; i.e., they aim to learn a mapping from the input…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Tao Chen , Chenhui Wang , Zhihao Chen , Yiming Lei , Hongming Shan

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Label scarcity remains a major challenge in deep learning-based medical image segmentation. Recent studies use strong-weak pseudo supervision to leverage unlabeled data. However, performance is often hindered by inconsistencies between…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Zhiqiang Shen , Peng Cao , Xiaoli Liu , Jinzhu Yang , Osmar R. Zaiane

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Khang Le , Anh Mai Vu , Thi Kim Trang Vo , Ha Thach , Ngoc Bui Lam Quang , Thanh-Huy Nguyen , Minh H. N. Le , Zhu Han , Chandra Mohan , Hien Van Nguyen

The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Aakash Madhav Rao , Debayan Gupta

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

Synthetic datasets are widely used for training urban scene recognition models, but even highly realistic renderings show a noticeable gap to real imagery. This gap is particularly pronounced when adapting to a specific target domain, such…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Denis Zavadski , Damjan Kalšan , Tim Küchler , Haebom Lee , Stefan Roth , Carsten Rother

Generative models, such as GANs and diffusion models, have been used to augment training sets and boost performances in different tasks. We focus on generative models for cell detection instead, i.e., locating and classifying cells in given…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Chen Li , Xiaoling Hu , Shahira Abousamra , Meilong Xu , Chao Chen

To synthesize high-fidelity samples, diffusion models typically require auxiliary data to guide the generation process. However, it is impractical to procure the painstaking patch-level annotation effort required in specialized domains like…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Alexandros Graikos , Srikar Yellapragada , Minh-Quan Le , Saarthak Kapse , Prateek Prasanna , Joel Saltz , Dimitris Samaras

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

In medical image segmentation, supervised deep networks' success comes at the cost of requiring abundant labeled data. While asking domain experts to annotate only one or a few of the cohort's images is feasible, annotating all available…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Devavrat Tomar , Behzad Bozorgtabar , Manana Lortkipanidze , Guillaume Vray , Mohammad Saeed Rad , Jean-Philippe Thiran

We present a framework to take advantage of existing labels at inference, called \textit{exemplars}, in order to improve the performance of object detection in medical images. The method, \textit{exemplar diffusion}, leverages existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Victor Wåhlstrand , Jennifer Alvén , Ida Häggström

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…