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Related papers: Research on Cumin Peptides Using PBS Extraction an…

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Cuminum cyminum L. (cumin) is a medicinal and edible plant widely used in traditional Chinese medicine (TCM) for treating various ailments, including diarrhea, abdominal pain, inflammation, asthma, and diabetes. While previous research has…

Other Quantitative Biology · Quantitative Biology 2025-02-04 Ermatov Ismoil , Sumairemu subuer , Rena awuti , Haili qian Taurtaihon , Ahmidin wali , Yasen Mijiti

Azurin and its derived peptides, notably p28, exhibit significant anticancer properties, primarily by stabilizing the tumor suppressor protein p53 and preventing its degradation. Previous studies have shown that p28 binds to p53's…

Soft Condensed Matter · Physics 2024-11-12 Albin Joy , Anand Srivastava , Rajib Biswas

Antimicrobial peptides are a class of small, usually positively charged amphiphilic peptides that are used by the innate immune system to combat bacterial infection in multicellular eukaryotes. Antimicrobial peptides are known for their…

Biomolecules · Quantitative Biology 2015-06-12 Natalia P. Rodina , Anna N. Yudenko , Ivan N. Terterov , Igor E. Eliseev

In this work we showcase the potential of peptides as versatile scaffolds for quantum computing and molecular spintronics. In particular, we focus on lanthanide-binding tags, which were originally developed in the field of biotechnology for…

Antimicrobial peptides (AMPs) play important roles in cancer, autoimmune diseases, and aging. A critical aspect of AMP functionality is their targeted interaction with pathogen membranes, which often possess altered lipid compositions.…

Short peptides with antimicrobial activity have therapeutic potential for treating bacterial infections. Mechanisms of actions for antimicrobial peptides require binding the biological membrane of their target, which often represents a key…

Biomolecules · Quantitative Biology 2021-11-05 Jacob M. Remington , Jonathon B. Ferrell , Jianing Li

Antimicrobial peptides (AMPs) have intrigued researchers for decades due to the contradiction between their high potential against resistant bacteria and the inability to find a structure-function relationship for the development of an…

Soft Condensed Matter · Physics 2025-02-14 Marta V. Volovik , Zaret G. Denieva , Oleg V. Kondrashov , Sergey A. Akimov , Oleg V. Batishchev

Efficient syntheses of some new substituted pyrazoline derivatives linked to substituted benzimidazole scaffold were performed by multistep reaction sequences. All the synthesized compounds were characterized using elemental analysis and…

Biomolecules · Quantitative Biology 2020-05-05 Gopal Krishna Padhy , Jagadeesh Panda , Ajaya Kumar Behera

A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 +…

Biomolecules · Quantitative Biology 2020-03-11 Qurat-ul-Ain , Shafqat Hussain , M. Iqbal Coudhary , Khalid Mohammed Khan

This work explores the antimicrobial efficacy of ZnO nanoparticles (NPs) films with varying microstructure, crystallographic orientation and surface roughness. Thin films with different microstructures were obtained by varying precursor…

Materials Science · Physics 2024-07-04 Imroi El-Habib , Sarah Dine , Alex Lemarchand , Christine Mielcarek , Mamadou Traore , Rabah Azouani

Development of the new antimicrobial agents against antibiotic resistance pathogens is the nowadays challenge. Antimicrobial peptides (AMP) occur as important defence agents in many organisms and offer a viable alternative to conventional…

Biomolecules · Quantitative Biology 2013-07-24 M. Pirtskhalava , B. Vishnepolsky , M. Grigolava

Objective: Total 186 biologically important phenylpropanoids and polyketides compounds from different Indian medicinal plants and dietary sources were screened to filter potential compounds that bind at the active site of the therapeutic…

Biomolecules · Quantitative Biology 2020-05-26 Seshu Vardhan , Bharat Z. Dholakiya , Suban K Sahoo

Antimicrobial biomaterials are critical to aid in the regeneration of oral soft tissue and prevent or treat localised bacterial infections. With the rising trend in antibiotic resistance, there is a pressing clinical need for new…

Tissues and Organs · Quantitative Biology 2021-01-06 Amy Contreras , Michael J. Raxworthy , Simon Wood , Jessica D. Schiffman , Giuseppe Tronci

Bayesian network models are finding success in characterizing enzyme-catalyzed reactions, slow conformational changes, predicting enzyme inhibition, and genomics. In this work, we apply them to statistical modeling of peptides by…

Applications · Statistics 2018-10-09 Rainier Barrett , Shaoyi Jiang , Andrew D White

Antimicrobial peptides (AMPs) are anti-infectives that have potential as a novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides imply interaction with cell envelope. Comprehensive understanding of…

Biomolecules · Quantitative Biology 2020-05-11 Malak Pirtskhalava , Boris Vishnepolsky , Maya Grigolava

Suillus species, in general, are edible mushrooms, and environmentally important that are associated mostly with pine trees in the tropics regions. These fungi considered a remarkable source of phenolic compounds that play a crucial role as…

Other Quantitative Biology · Quantitative Biology 2023-03-16 Shimal Yonuis Abdulhadi , Raghad Nawaf Gergees , Ghazwan Qasim Hasan

Peptide T is a synthetic octapeptide fragment, which corresponds to the region 185-192 of the gp120 HIV coat protein and functions as a viral entry inhibitor. In this work, a folding molecular dynamics simulation of peptide T in a…

Biomolecules · Quantitative Biology 2022-04-12 Ioanna Gkogka , Nicholas M. Glykos

Photodynamically active fibres (PAFs) are a novel class of stimulus-sensitive systems capable of triggering antibiotic-free antibacterial effect on-demand when exposed to light. Despite their relevance in infection control, however, the…

Tissues and Organs · Quantitative Biology 2021-01-07 Amy Contreras , Michael J. Raxworthy , Simon Wood , Giuseppe Tronci

Endophytes are tiny organisms present in living tissues of distinct plants and have been extensively studied for their endophytic microbial complement. Roots of Rosmarinus officinalis were subjected to the isolation of endophytic fungi and…

Genomics · Quantitative Biology 2023-03-10 Shimal Yonuis Abdulhadi , Ghazwan Qasim Hasan , Raghad Nawaf Gergees

Silicon photonics faces a persistent challenge in extending photodetection capabilities beyond the 1.6 um wavelength range, primarily due to the lack of appropriate epitaxial materials. Colloidal quantum dots (QDs) present a promising…

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