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Related papers: An Adaptive Proton FLASH Therapy Using Modularized…

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Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

Purpose: Recent studies suggest ultra-high dose rate (FLASH) irradiation can spare normal tissues from radiotoxicity, while efficiently controlling the tumor, and this is known as the FLASH effect. This study performed theoretical analyses…

Medical Physics · Physics 2021-09-02 Hongyu Zhu , Junli Li , Xiaowu Deng , Rui Qiu , Zhen Wu , Hui Zhang

Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

The purpose of this study is to determine whether organ sparing and target coverage can be simultaneously maintained for pencil beam scanning (PBS) proton therapy treatment of thoracic tumors in the presence of motion, stopping power…

Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…

Treatment planning uncertainties are typically managed using margin-based or robust optimization. Margin-based methods expand the clinical target volume (CTV) to a planning target volume, generally unsuited for proton therapy. Robust…

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

Quantitative Methods · Quantitative Biology 2024-09-19 Qingqing Wang , Chang Chang

In this paper we propose a solution to the need for a fast particle transport algorithm in Online Adaptive Proton Therapy capable of cheaply, but accurately computing the changes in patient dose metrics as a result of changes in the system…

Medical Physics · Physics 2022-08-26 Tiberiu Burlacu , Danny Lathouwers , Zoltán Perkó

Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…

Robust fine-tuning aims to achieve competitive in-distribution (ID) performance while maintaining the out-of-distribution (OOD) robustness of a pre-trained model when transferring it to a downstream task. Recently, projected gradient…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Junjiao Tian , Yen-Cheng Liu , James Seale Smith , Zsolt Kira

Recent advances in radar automatic target recognition (RATR) techniques utilizing deep neural networks have demonstrated remarkable performance, largely due to their robust generalization capabilities. To address the challenge for…

Signal Processing · Electrical Eng. & Systems 2025-01-24 Yangbo Zhou , Sen Liu , Hong-Wei Gao , Hai lin , Guohua Wei , Xiaoqing Wang , Xiao-Min Pan

Uncertainties such as setup and range errors can significantly compromise proton therapy. A discrete uncertainty set is often constructed to represent different uncertainty scenarios. A min-max robust optimization approach is then utilized…

Optimization and Control · Mathematics 2025-08-12 Zihang Qiu , Ali Ajdari , Mislav Bobić , Thomas Bortfeld , Dick den Hertog , Jannis Kurtz , Hoyeon Lee

Radiation therapy outcomes are decided by two key parameters, dose and timing, whose best values vary substantially across patients. This variability is especially critical in the treatment of brain cancer, where fractionated or staged…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

Purpose: Recent investigations of radiation-induced contrast enhancements (RICE) in brain tumor patients after proton therapy indicated variability in proton relative biological effectiveness (RBE) and increased radiosensitivity of the…

Integrated microwave photonic filters (IMPFs) emerge as promising candidates for advanced microwave systems owing to their distinctive combination of wide operational bandwidth, flexibility, and compact size. Nevertheless, the complex and…

Laser powder bed fusion (LPBF) is a widely used metal additive manufacturing technology. However, the accumulation of internal residual stress during printing can cause significant distortion and potential failure. Although various scan…

Computational Engineering, Finance, and Science · Computer Science 2024-04-12 Mian Qin , Junhao Ding , Shuo Qu , Xu Song , Charlie C. L. Wang , Wei-Hsin Liao

Pair atomic density fitting (PADF) is a promising strategy to reduce the scaling with system size of quantum chemical methods for the calculation of the correlation energy like the direct random phase approximation (RPA) or second-order…

Chemical Physics · Physics 2023-03-14 Edoardo Spadetto , Pier Herman Theodoor Philipsen , Arno Förster , Lucas Visscher

Rare-disease diagnosis remains one of the most pressing challenges in digital health, hindered by extreme data scarcity, privacy concerns, and the limited resources of edge devices. This paper proposes the Adaptive Federated Few-Shot…

Artificial Intelligence · Computer Science 2025-10-02 Aueaphum Aueawatthanaphisut

Remote photoplethysmography (rPPG) enables contactless vital sign monitoring using standard RGB cameras. However, existing methods rely on fixed parameters optimized for particular lighting conditions and camera setups, limiting…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Cecilia G. Morales , Fanurs Chi En Teh , Kai Li , Pushpak Agrawal , Artur Dubrawski

Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…

Medical Physics · Physics 2026-01-13 Christian Velten , Adam Bayliss , Jiayi Huang , Wolfgang A. Tomé