Related papers: An Adaptive Proton FLASH Therapy Using Modularized…

Phase aberration is an inherent side effect of ultrasound imaging due to the speed of sound inhomogeneity nature of human tissues, resulting in focusing error and reduced image contrast. This work introduces a phase aberration correction…

The authors propose robust adaptive strategies based on stochastic minimax optimization for a series of simulated treatments on a one-dimensional patient phantom. The plan applied during the first fractions should be able to handle…

This study investigates the response of Timepix3 semiconductor pixel detectors in proton beams of varying intensities, with a focus on FLASH proton therapy. Using the Timepix3 ASIC chip, we measured the spatial and spectral characteristics…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

Purpose: The importance of robust proton treatment planning to mitigate the impact of uncertainty is well understood. However, its computational cost grows with the number of uncertainty scenarios, prolonging the treatment planning process.…

In the field of digital signal processing, the fast Fourier transform (FFT) is a fundamental algorithm, with its processors being implemented using either the pipelined architecture, well-known for high-throughput applications but weak in…

We developed a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources efficiently and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries. Our IMPAT…

Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…

Purpose: To develop a model-based nonlinear reconstruction for simultaneous water-specific $T_{1}$, $R_{2}^{*}$, $B_{0}$ field and/or fat fraction (FF) mapping using single-shot inversion-recovery (IR) multi-echo radial FLASH. Methods: The…

Purpose: To demonstrate the feasibility of fast Monte Carlo (MC) based inverse biological planning for the treatment of head and neck tumors in spot-scanning proton therapy. Methods: Recently, a fast and accurate Graphics Processor Unit…

Phase-shifted carrier pulse-width modulation (PSC-PWM) is a widely adopted scheduling algorithm in cascaded bridge converters, modular multilevel converters, and reconfigurable batteries. However, non-uniformed pulse widths for the modules…

We report a fully integrated microwave photonic passband filter on a silicon photonic chip. The on-chip integrated microwave photonic filter (IMPF) consists of a high-speed phase modulator (PM), a thermally tunable high-Q micro-disk…

This paper presents the design of a rapid cycling synchrotron (RCS) featuring a longitudinal localized kick driven fast extraction system for three-dimensional (3D) pencil beam scanning (PBS) proton FLASH delivery. The extraction method is…

Integrated photonic chips have significant potential in telecommunications, classic computing, quantum systems, and topological photonics. Direct laser writing offers unique capability for creating three-dimensional photonic devices in an…

The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostatic lesion (DIL) boost represents a significant advancement in…

Learning solutions of partial differential equations (PDEs) with Physics-Informed Neural Networks (PINNs) is an attractive alternative approach to traditional solvers due to its flexibility and ease of incorporating observed data. Despite…

Purpose: Commercial UHDR platforms deliver Ultra-High Dose Rate (UHDR) doses at discrete combinations of pulse parameters including pulse width (PW), pulse repetition frequency (PRF) and number of pulses (N), which dictate unique…

The Perception-Distortion tradeoff (PD-tradeoff) theory suggests that face restoration algorithms must balance perceptual quality and fidelity. To achieve minimal distortion while maintaining perfect perceptual quality, Posterior-Mean…

Background: With the advent of Intensity Modulated Radiotherapy (IMRT) and recently, Volumetric Modulated Arc Therapy (VMAT), treatment planning using Flattening Filter Free (FFF) beams can meet all of the energy requirements in radiation…

Neural Radiance Fields (NeRF)-based models have achieved remarkable success in 3D reconstruction and rendering tasks. However, during both training and inference, these models rely heavily on dense point sampling along rays from multiple…