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Language models (LMs) have demonstrated remarkable capabilities in NLP, yet adapting them efficiently and robustly to specific tasks remains challenging. As their scale and complexity grow, fine-tuning LMs on labelled data often…

Computation and Language · Computer Science 2025-06-27 Zhengyan Shi

Unsupervised large-scale vision-language pre-training has shown promising advances on various downstream tasks. Existing methods often model the cross-modal interaction either via the similarity of the global feature of each modality which…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Lewei Yao , Runhui Huang , Lu Hou , Guansong Lu , Minzhe Niu , Hang Xu , Xiaodan Liang , Zhenguo Li , Xin Jiang , Chunjing Xu

Language models have steadily increased in size over the past few years. They achieve a high level of performance on various natural language processing (NLP) tasks such as question answering and summarization. Large language models (LLMs)…

Computation and Language · Computer Science 2023-01-31 Jessica Huynh , Cathy Jiao , Prakhar Gupta , Shikib Mehri , Payal Bajaj , Vishrav Chaudhary , Maxine Eskenazi

Large-scale Protein Language Models (PLMs) have improved performance in protein prediction tasks, ranging from 3D structure prediction to various function predictions. In particular, AlphaFold, a ground-breaking AI system, could potentially…

Quantitative Methods · Quantitative Biology 2022-10-18 Mingyang Hu , Fajie Yuan , Kevin K. Yang , Fusong Ju , Jin Su , Hui Wang , Fei Yang , Qiuyang Ding

Low-shot image classification, where training images are limited or inaccessible, has benefited from recent progress on pre-trained vision-language (VL) models with strong generalizability, e.g. CLIP. Prompt learning methods built with VL…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Zhaoheng Zheng , Jingmin Wei , Xuefeng Hu , Haidong Zhu , Ram Nevatia

Recent advancements in unsupervised protein language models (ProteinLMs), like ESM-1b and ESM-2, have shown promise in different protein prediction tasks. However, these models face challenges due to their high computational demands,…

Machine Learning · Computer Science 2023-10-31 Shuang Peng , Fei Yang , Ning Sun , Sheng Chen , Yanfeng Jiang , Aimin Pan

Probabilistic programming offers a powerful framework for modeling uncertainty, yet statistical model discovery in this domain entails navigating an immense search space under strict domain-specific constraints. When small language models…

Machine Learning · Computer Science 2026-04-21 Madhav Kanda , Shubham Ugare , Sasa Misailovic

Recent advances in reasoning with large language models (LLMs) have demonstrated strong performance on complex mathematical tasks, including combinatorial optimization. Techniques such as Chain-of-Thought and In-Context Learning have…

Artificial Intelligence · Computer Science 2025-09-17 Marylou Fauchard , Florian Carichon , Margarida Carvalho , Golnoosh Farnadi

Protein research is crucial in various fundamental disciplines, but understanding their intricate structure-function relationships remains challenging. Recent Large Language Models (LLMs) have made significant strides in comprehending…

Computational Engineering, Finance, and Science · Computer Science 2025-01-24 Chao Wang , Hehe Fan , Ruijie Quan , Yi Yang

Small Language Models (SLMs) have become increasingly important due to their efficiency and performance to perform various language tasks with minimal computational resources, making them ideal for various settings including on-device,…

We propose an efficient evaluation protocol for large vision-language models (VLMs). Given their broad knowledge and reasoning capabilities, multiple benchmarks are needed for comprehensive assessment, making evaluation computationally…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Teppei Suzuki , Keisuke Ozawa

Training large language models (LLMs) efficiently while preserving model quality poses significant challenges, particularly with subbyte precision supported by state-of-the-art GPUs. Current mixed-precision training approaches either apply…

Machine Learning · Computer Science 2026-02-03 Yunjie Pan , Yongyi Yang , Hanmei Yang , Scott Mahlke

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

Vision-language models (VLMs) have demonstrated exceptional generalization capabilities for downstream tasks. Due to its efficiency, prompt learning has gradually become a more effective and efficient method for transferring VLMs to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Chenhao Ding , Xinyuan Gao , Songlin Dong , Jizhou Han , Qiang Wang , Zhengdong Zhou , Yuhang He , Yihong Gong

Proteins are complex molecules responsible for different functions in nature. Enhancing the functionality of proteins and cellular fitness can significantly impact various industries. However, protein optimization using computational…

Machine Learning · Computer Science 2024-05-30 Minji Lee , Luiz Felipe Vecchietti , Hyunkyu Jung , Hyun Joo Ro , Meeyoung Cha , Ho Min Kim

The recent development of Large Language Models (LLMs) has been accompanied by an effervescence of novel ideas and methods to better optimize the loss of deep learning models. Claims from those methods are myriad: from faster convergence to…

Machine Learning · Computer Science 2025-09-03 Andrei Semenov , Matteo Pagliardini , Martin Jaggi

Despite the recent ubiquity of large language models and their high zero-shot prompted performance across a wide range of tasks, it is still not known how well they perform on tasks which require processing of potentially idiomatic…

Computation and Language · Computer Science 2024-05-16 Dylan Phelps , Thomas Pickard , Maggie Mi , Edward Gow-Smith , Aline Villavicencio

Although massive pre-trained vision-language models like CLIP show impressive generalization capabilities for many tasks, still it often remains necessary to fine-tune them for improved performance on specific datasets. When doing so, it is…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Moritz Ibing , Isaak Lim , Leif Kobbelt

Training large language models (LLMs) from scratch requires significant computational resources, driving interest in developing smaller, domain-specific LLMs that maintain both efficiency and strong task performance. Medium-sized models…

Computation and Language · Computer Science 2026-03-02 Chaitali Bhattacharyya , Hyunsei Lee , Junyoung Lee , Shinhyoung Jang , Il hong Suh , Yeseong Kim

Latent representation alignment has become a foundational technique for constructing multimodal large language models (MLLM) by mapping embeddings from different modalities into a shared space, often aligned with the embedding space of…

Machine Learning · Computer Science 2025-03-06 Dong Shu , Bingbing Duan , Kai Guo , Kaixiong Zhou , Jiliang Tang , Mengnan Du
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