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The spread of one disease, in some cases, can stimulate the spreading of another infectious disease. Here, we treat analytically a symmetric coinfection model for spreading of two diseases on a two-layer multiplex network. We allow layer…

Physics and Society · Physics 2016-04-20 N. Azimi-Tafreshi

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

Populations and Evolution · Quantitative Biology 2023-08-04 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua S. Weitz , Andrew A. Peterson

Widely used models in genetics include the Wright-Fisher diffusion and its moment dual, Kingman's coalescent. Each has a multilocus extension but under neither extension is the sampling distribution available in closed-form, and their…

Probability · Mathematics 2015-06-24 Paul A. Jenkins , Paul Fearnhead , Yun S. Song

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

The shape of an epidemic wave in simple epidemic models applies to a homogeneous distribution of infected people in the population. In large inhomogeneous systems, at country-scale for instance, the wave shape is similar except for the…

Chemical Physics · Physics 2022-11-21 L. Vanel

We are interested in the evolving genealogy of a birth and death process with trait structure and ecological interactions. Traits are hereditarily transmitted from a parent to its offspring unless a mutation occurs. The dynamics may depend…

Probability · Mathematics 2012-06-20 Sylvie Méléard , Viet Chi Tran

In this paper we study a mathematical model for an infectious disease such as Cholera without life-time immunity. Due to the different mobility for susceptible, infected human and recovered human hosts, the diffusion coefficients are…

Analysis of PDEs · Mathematics 2020-11-18 Hong-Ming Yin

We present an analysis of six deterministic models for epidemic spreading. The evolution of the number of individuals of each class is given by ordinary differential equations of the first order in time, which are set up by using the laws…

Biological Physics · Physics 2020-12-25 Tânia Tomé , Mário J. de Oliveira

When an advantageous mutation occurs in a population, the favorable allele may spread to the entire population in a short time, an event known as a selective sweep. As a result, when we sample $n$ individuals from a population and trace…

Probability · Mathematics 2007-05-23 Rick Durrett , Jason Schweinsberg

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

The analysis of contagion-diffusion processes in metapopulations is a powerful theoretical tool to study how mobility influences the spread of communicable diseases. Nevertheless, many metapopulation approaches use indistinguishable agents…

Physics and Society · Physics 2022-04-20 Pablo Valgañón , David Soriano-Paños , Alex Arenas , Jesús Gómez-Gardeñes

The statistics of outbreaks in a model for the propagation of meningococcal diseases is analyzed, taking into account the possibility that the population is fragmented into weakly connected patches. It is shown that, depending on the size…

Populations and Evolution · Quantitative Biology 2007-05-23 F. Guinea , V. A. A. Jansen , N. Stollenwerk

Traditional biomedical approaches treat diseases in isolation, but the importance of synergistic disease interactions is now recognized. As a first step we present and analyze a simple coinfection model for two diseases affecting…

Dynamical Systems · Mathematics 2015-04-21 Marcos Marvá , Ezio Venturino , Rafael Bravo de la Parra

Nosocomial infections have important consequences for patients and hospital staff: they worsen patient outcomes and their management stresses already overburdened health systems. Accurate judgements of whether an infection is nosocomial…

Variation in a sample of molecular sequence data informs about the past evolutionary history of the sample's population. Traditionally, Bayesian modeling coupled with the standard coalescent, is used to infer the sample's bifurcating…

Applications · Statistics 2024-10-22 Julie Zhang , Julia A. Palacios

Metapopulation models are commonly used in ecology, evolution, and epidemiology. These models usually entail homogeneity assumptions within patches and study networks of migration between patches to generate insights into conservation of…

Populations and Evolution · Quantitative Biology 2025-06-06 Diepreye Ayabina , Hasan Sevil , Adam Kleczkowski , M. Gabriela M. Gomes

Many real networks are not isolated from each other but form networks of networks, often interrelated in non trivial ways. Here, we analyze an epidemic spreading process taking place on top of two interconnected complex networks. We develop…

Disordered Systems and Neural Networks · Physics 2015-06-04 Anna Saumell-Mendiola , M. Ángeles Serrano , Marián Boguñá

We introduce a new type of point process model to describe the incidence of contagious diseases. The model is a variant of the Hawkes self-exciting process and exhibits similar clustering but without the restriction that the component…

Methodology · Statistics 2017-03-27 Frederic Schoenberg , Marc Hoffmann , Ryan Harrigan

We consider a threshold epidemic model on a clustered random graph with overlapping communities. In other words, our epidemic model is such that an individual becomes infected as soon as the proportion of her infected neighbors exceeds the…

Probability · Mathematics 2014-02-03 Emilie Coupechoux , Marc Lelarge

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang
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