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Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

Large-scale diffusion models have achieved remarkable success in generating high-quality images from textual descriptions, gaining popularity across various applications. However, the generation of layered content, such as transparent…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Yusuf Dalva , Yijun Li , Qing Liu , Nanxuan Zhao , Jianming Zhang , Zhe Lin , Pinar Yanardag

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

High-quality, large-scale data is essential for robust deep learning models in medical applications, particularly ultrasound image analysis. Diffusion models facilitate high-fidelity medical image generation, reducing the costs associated…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Pooria Ashrafian , Milad Yazdani , Moein Heidari , Dena Shahriari , Ilker Hacihaliloglu

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Over the last three to five years, it has become possible to generate machine learning synthetic data for healthcare-related uses. However, concerns have been raised about potential negative factors associated with the possibilities of…

This survey reviews how large language models (LLMs) are transforming synthetic training data generation in both natural language and code domains. By producing artificial but task-relevant examples, these models can significantly augment…

Computation and Language · Computer Science 2025-11-21 Mihai Nadas , Laura Diosan , Andreea Tomescu

Health disparities are differences in health outcomes and access to healthcare between different groups, including racial and ethnic minorities, low-income people, and rural residents. An artificial intelligence (AI) program called large…

Computation and Language · Computer Science 2023-10-31 Yohn Jairo Parra Bautista , Vinicious Lima , Carlos Theran , Richard Alo

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Xin Huang , Junjie Liang , Qingshan Hou , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Training fall detection systems is challenging due to the scarcity of real-world fall data, particularly from elderly individuals. To address this, we explore the potential of Large Language Models (LLMs) for generating synthetic fall data.…

Computation and Language · Computer Science 2025-05-09 Sana Alamgeer , Yasine Souissi , Anne H. H. Ngu

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

In this research, we introduce an innovative method for synthesizing medical images using generative adversarial networks (GANs). Our proposed GANs method demonstrates the capability to produce realistic synthetic images even when trained…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yinqiu Feng , Bo Zhang , Lingxi Xiao , Yutian Yang , Tana Gegen , Zexi Chen

The scarcity of accessible, compliant, and ethically sourced data presents a considerable challenge to the adoption of artificial intelligence (AI) in sensitive fields like healthcare, finance, and biomedical research. Furthermore, access…

Machine Learning · Computer Science 2025-04-02 Kumar Kshitij Patel , Weitong Zhang , Lingxiao Wang

This paper explores the burgeoning field of 3D content generation within the landscape of Artificial Intelligence Generated Content (AIGC) and large-scale models. It investigates innovative methods like Text-to-3D and Image-to-3D, which…

Graphics · Computer Science 2024-05-27 Ke Zhao , Andreas Larsen

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

The advancement of generative AI, particularly in medical imaging, confronts the trilemma of ensuring high fidelity, diversity, and efficiency in synthetic data generation. While Generative Adversarial Networks (GANs) have shown promise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lorenzo Tronchin , Tommy Löfstedt , Paolo Soda , Valerio Guarrasi

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang