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The generation of realistic medical images from text descriptions has significant potential to address data scarcity challenges in healthcare AI while preserving patient privacy. This paper presents a comprehensive study of text-to-image…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Mikhail Chaichuk , Sushant Gautam , Steven Hicks , Elena Tutubalina

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Marvin Seyfarth , Salman Ul Hassan Dar , Isabelle Ayx , Matthias Alexander Fink , Stefan O. Schoenberg , Hans-Ulrich Kauczor , Sandy Engelhardt

Generating synthetic text addresses the challenge of data availability in privacy-sensitive domains such as healthcare. This study explores the applicability of synthetic data in real-world medical settings. We introduce MedSyn, a novel…

Computation and Language · Computer Science 2024-09-05 Gleb Kumichev , Pavel Blinov , Yulia Kuzkina , Vasily Goncharov , Galina Zubkova , Nikolai Zenovkin , Aleksei Goncharov , Andrey Savchenko

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

The emergence of synthetic data represents a pivotal shift in modern machine learning, offering a solution to satisfy the need for large volumes of data in domains where real data is scarce, highly private, or difficult to obtain. We…

Computation and Language · Computer Science 2024-08-19 Krisztian Balog , John Palowitch , Barbara Ikica , Filip Radlinski , Hamidreza Alvari , Mehdi Manshadi

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

How capable are diffusion models of generating synthetics texts? Recent research shows their strengths, with performance reaching that of auto-regressive LLMs. But are they also good in generating synthetic data if the training was under…

Computation and Language · Computer Science 2024-10-31 Sebastian Ochs , Ivan Habernal

Generative image models have achieved remarkable progress in both natural and medical imaging. In the medical context, these techniques offer a potential solution to data scarcity-especially for low-prevalence anomalies that impair the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Gregory Schuit , Denis Parra , Cecilia Besa

This study evaluates the linguistic and clinical suitability of synthetic electronic health records in mental health. First, we describe the rationale and the methodology for creating the synthetic corpus. Second, we examine expressions of…

Computation and Language · Computer Science 2026-02-05 Serge Sharoff , John Baker , David Francis Hunt , Alan Simpson

Recent advancements in artificial intelligence (AI), especially large language models (LLMs), have significantly advanced healthcare applications and demonstrated potentials in intelligent medical treatment. However, there are conspicuous…

Computation and Language · Computer Science 2025-05-26 Qinkai Yu , Mingyu Jin , Dong Shu , Chong Zhang , Lizhou Fan , Wenyue Hua , Suiyuan Zhu , Yanda Meng , Zhenting Wang , Mengnan Du , Yongfeng Zhang

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Healthcare industries face challenges when experiencing rare diseases due to limited samples. Artificial Intelligence (AI) communities overcome this situation to create synthetic data which is an ethical and privacy issue in the medical…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Al Amin , Kamrul Hasan , Saleh Zein-Sabatto , Liang Hong , Sachin Shetty , Imtiaz Ahmed , Tariqul Islam

This review introduces the transformative potential of generative Artificial Intelligence (AI) and foundation models, including large language models (LLMs), for health technology assessment (HTA). We explore their applications in four…

Machine Learning · Computer Science 2024-09-24 Rachael Fleurence , Jiang Bian , Xiaoyan Wang , Hua Xu , Dalia Dawoud , Mitch Higashi , Jagpreet Chhatwal

The rapid advancement of Artificial Intelligence (AI) has catalyzed revolutionary changes across various sectors, notably in healthcare. In particular, generative AI-led by diffusion models and transformer architectures-has enabled…

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay…

Computation and Language · Computer Science 2023-04-12 Ruixiang Tang , Xiaotian Han , Xiaoqian Jiang , Xia Hu

Collecting and annotating medical images is a time-consuming and resource-intensive task. However, generating synthetic data through models such as Diffusion offers a cost-effective alternative. This paper introduces a new method for the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Ruochen Pi , Lianlei Shan

This paper explores the use of large language models (LLMs) to assist in the development of new disease modules for Synthea, an open-source synthetic health data generator. Incorporating LLMs into the module development process has the…

Artificial Intelligence · Computer Science 2025-07-30 Mark A. Kramer , Aanchal Mathur , Caroline E. Adams , Jason A. Walonoski