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Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…
The remarkable advancements in our capacity to synthesise structured light have facilitated the generation of any desired optical landscapes and even controlling the spatial distribution of light propagating through optically complex media…
We report on the 3-dimensional imaging of biological cells including living neurons by a recently developed fibered interferometric Scanning Optical Microscope. The topography and surface structure of mouse fibroblasts and hippocampal…
Multifocus microscopy enables recording of entire volumes in a single camera exposure. In dense samples, multifocus microscopy is severely hampered by background haze. Here, we introduce a scalable multifocus method that incorporates…
Polarization microscopy provides insights into the structure and orientational organization of biomolecules and their architectures in cells. The above key functional signatures, which are natively 3D, can be only detected in 2D for a…
High spatio-angular resolution diffusion MRI (dMRI) has been shown to provide accurate identification of complex neuronal fiber configurations, albeit, at the cost of long acquisition times. We propose a method to recover intra-voxel fiber…
We are now moving into an era where multi-object wide-field surveys, which traditionally use single fibres to observe many targets simultaneously, can exploit compact integral field units in place of single fibres. Current multi-object…
We report an angle-tilted, wavelength-multiplexed ptychographic modulation approach for multispectral lensless on-chip microscopy. In this approach, we illuminate the specimen with lights at 5 wavelengths simultaneously. A prism is added at…
Advanced radio-frequency pulse design used in magnetic resonance imaging has recently been demonstrated with deep learning of (convolutional) neural networks and reinforcement learning. For two-dimensionally selective radio-frequency…
We report a new coherent imaging technique, termed ptychographic structured modulation (PSM), for quantitative super-resolution microscopy. In this technique, we place a thin diffuser (i.e., a scattering lens) in between the sample and the…
Light transport in a highly multimode fiber exhibits complex behavior in space, time, frequency and polarization, especially in the presence of mode coupling. The newly developed techniques of spatial wavefront shaping turn out to be highly…
When an optical pulse is focused into a multimode waveguide or fiber, the energy is divided among the available guided modes. Consequently, the initially localized intensity spreads transversely, the spatial profile undergoes rapid…
A single-pixel digital holography system with phase-encoded illumination using a digital micromirror device (DMD) as a spatial light modulator (SLM) is presented. The enhanced switching rate of DMDs, far exceeding the stringent frame-rate…
The possibility of performing time-resolved spectroscopic studies in the molecular fingerprinting region or extending the cut-off wavelength of high-harmonic generation has recently boosted the development of efficient mid-infrared…
We present a novel, parameter-efficient and practical fully convolutional neural network architecture, termed InfiNet, aimed at voxel-wise semantic segmentation of infant brain MRI images at iso-intense stage, which can be easily extended…
Ultrasound Localization Microscopy can resolve the microvascular bed down to a few micrometers. To achieve such performance microbubble contrast agents must perfuse the entire microvascular network. Microbubbles are then located…
A simple imaging system together with complex semidefinite programming is used to generate the transmission matrix of a multimode fiber. Once the transmission matrix is acquired, we can modulate the phase of the input signal to induce…
The lensless endoscope (LE) is a promising device to acquire in vivo images at a cellular scale. The tiny size of the probe enables a deep exploration of the tissues. Lensless endoscopy with a multicore fiber (MCF) commonly uses a spatial…
Wavefront shaping has revolutionized imaging deep in scattering media, being able to spatially and temporally refocus light through or inside the medium. However, wavefront shaping is not compatible yet with polarization-resolved microscopy…
Active feedback control in magnetic confinement fusion devices is desirable to mitigate plasma instabilities and enable robust operation. Optical high-speed cameras provide a powerful, non-invasive diagnostic and can be suitable for these…