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The integration density of photonic integrated circuits has been limited by light coupling between waveguides. Traditional approaches to layout the waveguide with high density are based on refractive index engineering to suppress the light…
We propose a marginal super-resolution (MSR) approach based on 2D convolutional neural networks (CNNs) for interpolating an anisotropic brain magnetic resonance scan along the highly under-sampled direction, which is assumed to axial…
We present a novel method for estimation of the fiber orientation distribution (FOD) function based on diffusion-weighted Magnetic Resonance Imaging (D-MRI) data. We formulate the problem of FOD estimation as a regression problem through…
The research enterprise towards achieving high-performance hollow-core photonic crystal fibers has led to impressive advancements in the latest years. Indeed, using this family of fibers becomes nowadays an overarching strategy for building…
When light passes through a multimode fiber, two-dimensional random intensity patterns are formed due to the complex interference within the fiber. The extreme sensitivity of speckle patterns to the frequency of light paved the way for…
Purpose: Some advanced RF pulses, like multi-dimensional RF pulses, are often long and require substantial computation time due to a number of constraints and requirements, sometimes hampering clinical use. However, the pulses offer…
Manual operation of microscopes for repetitive tasks in cell biology is a significant bottleneck, consuming invaluable expert time, and introducing human error. Automation is essential, and while Digital Holographic Microscopy (DHM) offers…
Transmission matrix (TM) allows light control through complex media such as multimode fibers (MMFs), gaining great attention in areas like biophotonics over the past decade. The measurement of a complex-valued TM is highly desired as it…
When light propagates through a multimode optical fibre (MMF), the spatial information it carries is scrambled. Wavefront shaping can undo this scrambling, typically one spatial mode at a time - enabling deployment of MMFs as ultra-thin…
Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…
Multi-mode fibers provide an increased amount of data transfer rates given a large number of transmission modes. Unfortunately, the increased number of modes in a multi-mode fiber hinders the accurate transfer of information due to…
Optical imaging through scattering media is a fundamental challenge in many applications. Recently, substantial breakthroughs such as imaging through biological tissues and looking around corners have been obtained by the use of…
Recent years have witnessed the tremendous development of fusing fiber-optic imaging with supervised deep learning to enable high-quality imaging of hard-to-reach areas. Nevertheless, the supervised deep learning method imposes strict…
With recent developments in microscopy, such as stimulated emission depletion (STED) microscopy, far-field imaging at resolutions better than the diffraction limit is now a commercially available technique. Here, we show that, in the…
The use of structured ultrashort pulses with coupled spatiotemporal properties is emerging as a key tool for ultrafast manipulation. Ultrafast vector beams are opening exciting opportunities in different fields such as microscopy,…
Microfluidic systems with integrated sensors are ideal platforms to study and emulate processes such as complex multiphase flow and reactive transport in porous media, numerical modeling of bulk systems in medicine, and in engineering.…
Super-resolution microscopes (such as STED) illuminate samples with a tiny spot, and achieve very high resolution. But structures smaller than the spot cannot be resolved in this way. Therefore, we propose a technique to solve this problem.…
Purpose To alleviate the spatial encoding limitations of single-shot EPI by developing multi-shot segmented EPI for ultra-high-resolution fMRI with reduced ghosting artifacts from subject motion and respiration. Methods Segmented EPI can…
Multiphoton microscopes employ femtosecond lasers as light sources because the high peak power of the ultrashort pulse allows for multiphoton excitation of fluorescence in the examined sample. However, such short pulses are susceptible to…
Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…