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This paper presents a highly speculative model encompassing the cortex, thalamus, and hippocampus of the mammalian brain. While the majority of computational neuroscience models are founded upon empirical evidence, this model is predicated…

Neurons and Cognition · Quantitative Biology 2024-05-22 Valentin Puente-Varona

The hierarchical organization of the brain is a fundamental structural principle, while brain criticality is a leading hypothesis for its collective dynamics. However, the connection between structure and signatures of criticality remains…

Neurons and Cognition · Quantitative Biology 2026-04-24 Gustavo G. Cambrainha , Daniel M. Castro , Leonardo L. Gollo , Pedro V. Carelli , Mauro Copelli

Despite the rapid pace at which deep networks are improving on standardized vision benchmarks, they are still outperformed by humans on real-world vision tasks. One solution to this problem is to make deep networks more brain-like. Although…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Niranjan Rajesh , Georgin Jacob , SP Arun

What do societies, the Internet, and the human brain have in common? They are all examples of complex relational systems, whose emerging behaviours are largely determined by the non-trivial networks of interactions among their constituents,…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Vito Latora

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Deep learning continues to play as a powerful state-of-art technique that has achieved extraordinary accuracy levels in various domains of regression and classification tasks, including images, video, signal, and natural language data. The…

Neural and Evolutionary Computing · Computer Science 2022-06-03 Anna Zou , Zhiyuan Li

The need for high-throughput, precise, and meaningful methods for measuring behavior has been amplified by our recent successes in measuring and manipulating neural circuitry. The largest challenges associated with moving in this direction,…

Biological Physics · Physics 2017-12-18 Gordon J. Berman

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

Neurons and Cognition · Quantitative Biology 2012-03-06 Xuejuan Zhang , Jianfeng Feng

Functional differentiation in the brain emerges as distinct regions specialize and is key to understanding brain function as a complex system. Previous research has modeled this process using artificial neural networks with specific…

Neurons and Cognition · Quantitative Biology 2025-11-17 Yuki Tomoda , Ichiro Tsuda , Yutaka Yamaguti

The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu

Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

Machine Learning · Statistics 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

The human brain displays rich communication dynamics that are thought to be particularly well-reflected in its marked community structure. Yet, the precise relationship between community structure in structural brain networks and the…

Neurons and Cognition · Quantitative Biology 2020-12-23 Shubhankar P. Patankar , Jason Z. Kim , Fabio Pasqualetti , Danielle S. Bassett

With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…

Molecular Networks · Quantitative Biology 2010-01-28 Sitabhra Sinha , T Jesan , Nivedita Chatterjee

The principle of self-organization has acquired a fundamental significance in the newly emerging field of computational philosophy. Self-organizing systems have been described in various domains in science and philosophy including physics,…

Neurons and Cognition · Quantitative Biology 2020-11-12 Birgitta Dresp-Langley

Dynamics play a critical role in computation. The principled evolution of states over time enables both biological and artificial networks to represent and integrate information to make decisions. In the past few decades, significant…

Neurons and Cognition · Quantitative Biology 2023-11-28 Jason Z. Kim , Bart Larsen , Linden Parkes

The accumulation of adaptations in an open-ended manner during lifetime learning is a holy grail in reinforcement learning, intrinsic motivation, artificial curiosity, and developmental robotics. We present a specification for a cognitive…

Artificial Intelligence · Computer Science 2013-03-29 Chrisantha Fernando , Vera Vasas

The increasing availability of brain data within and outside the biomedical field, combined with the application of artificial intelligence (AI) to brain data analysis, poses a challenge for ethics and governance. We identify distinctive…