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Analyzing the brain in terms of organizational structures at intermediate scales provides an approach to negotiate the complexity arising from interactions between its large number of components. Focusing on a wiring diagram that spans the…

Neurons and Cognition · Quantitative Biology 2023-01-10 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

The human organism is an integrated network where complex physiologic systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network. Identifying and…

Data Analysis, Statistics and Probability · Physics 2012-03-02 Amir Bashan , Ronny P. Bartsch , Jan W. Kantelhardt , Shlomo Havlin , Plamen Ch. Ivanov

The underlying physiological mechanisms of generating conscious states are still unknown. To make progress on the problem of consciousness, we will need to experimentally design a system that evolves in a similar way our brains do. Recent…

Emerging Technologies · Computer Science 2014-11-20 Dorian Aur

Function and dysfunctions of neural systems are tied to the temporal evolution of neural states. The current limitations in showing their causal role stem largely from the absence of tools capable of probing the brain's internal state in…

Neurons and Cognition · Quantitative Biology 2024-09-24 Ayesha Vermani , Matthew Dowling , Hyungju Jeon , Ian Jordan , Josue Nassar , Yves Bernaerts , Yuan Zhao , Steven Van Vaerenbergh , Il Memming Park

Recent characterisations of self-organising systems depend upon the presence of a Markov blanket: a statistical boundary that mediates the interactions between what is inside of and outside of a system. We leverage this idea to provide an…

Neurons and Cognition · Quantitative Biology 2020-06-05 Ines Hipolito , Maxwell Ramstead , Laura Convertino , Anjali Bhat , Karl Friston , Thomas Parr

Functional brain imaging allows measuring dynamic functionality in all brain regions. It is broadly used in clinical cognitive neuroscience as, well as in research. It will allow the observation of neural activities in the brain…

Medical Physics · Physics 2016-04-01 Saman Sarraf , Jian Sun

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Neuronal circuits of the cerebral cortex are the structural basis of mammalian cognition. The same qualitative components and connectivity motifs are repeated across functionally specialized cortical areas and mammalian species, suggesting…

Neurons and Cognition · Quantitative Biology 2025-07-04 Arno Granier , Katharina A Wilmes , Mihai A Petrovici , Walter Senn

Human brain dynamics can be profitably viewed through the lens of statistical mechanics, where neurophysiological activity evolves around and between local attractors representing preferred mental states. Many physically-inspired models of…

Neurons and Cognition · Quantitative Biology 2016-09-06 Arian Ashourvan , Shi Gu , Marcelo G. Mattar , Jean M. Vettel , Danielle S. Bassett

The field of neuroscience is facing an unprecedented expanse in the volume and diversity of available data. Traditionally, network models have provided key insights into the structure and function of the brain. With the advent of big data…

Neurons and Cognition · Quantitative Biology 2018-02-14 Michael Vaiana , Sarah Muldoon

The exploration of brain-heart interactions within various paradigms, including affective computing, human-computer interfaces, and sensorimotor evaluation, stands as a significant milestone in biomarker development and neuroscientific…

Other Quantitative Biology · Quantitative Biology 2026-04-27 Diego Candia-Rivera , Luca Faes , Fabrizio De Vico Fallani , Mario Chavez

The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive…

Emerging Technologies · Computer Science 2025-11-04 Yannic Talavera , Bernd Ulmann

Network neuroscience represents the brain as a collection of regions and inter-regional connections. Given its ability to formalize systems-level models, network neuroscience has generated unique explanations of neural function and…

Neurons and Cognition · Quantitative Biology 2019-11-13 Maxwell A. Bertolero , Danielle S. Bassett

In neuroscience, an important aspect of understanding the function of a neural circuit is to determine which, if any, of the neurons in the circuit are vital for the biological behavior governed by the neural circuit. A similar problem is…

Computational Complexity · Computer Science 2020-06-24 Vidya Sagar Sharma , Piyush Srivastava

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Polymorphism in the peripheral sensory system (e.g., congenital individual differences in photopigment configuration) is important in diverse research fields, ranging from evolutionary biology to engineering, because of its potential…

Neurons and Cognition · Quantitative Biology 2017-01-10 Satohiro Tajima

The anatomically layered structure of a human brain results in leveled functions. In all these levels of different functions, comparison, feedback and imitation are the universal and crucial mechanisms. Languages, symbols and tools play key…

Neurons and Cognition · Quantitative Biology 2018-02-07 Shengyong Xu , Jingjing Xu , Rujun Dai

Modern neuroimaging techniques provide us with unique views on brain structure and function; i.e., how the brain is wired, and where and when activity takes place. Data acquired using these techniques can be analyzed in terms of its network…

Image and Video Processing · Electrical Eng. & Systems 2018-01-31 Weiyu Huang , Thomas A. W. Bolton , John D. Medaglia , Danielle S. Bassett , Alejandro Ribeiro , Dimitri Van De Ville

The great behavioral heterogeneity observed between individuals with the same psychiatric disorder and even within one individual over time complicates both clinical practice and biomedical research. However, modern technologies are an…

Neurons and Cognition · Quantitative Biology 2023-05-25 Michaela Ennis
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