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Aligning large language models (LLMs) with human expectations requires high-quality instructional dialogues, which usually require instructions that are diverse and in-depth. Existing methods leverage two LLMs to interact for automatic…

Computation and Language · Computer Science 2024-10-01 Jiao Ou , Jiayu Wu , Che Liu , Fuzheng Zhang , Di Zhang , Kun Gai

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

Computation and Language · Computer Science 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Computation and Language · Computer Science 2025-03-25 Nicholas Wan , Qiao Jin , Joey Chan , Guangzhi Xiong , Serina Applebaum , Aidan Gilson , Reid McMurry , R. Andrew Taylor , Aidong Zhang , Qingyu Chen , Zhiyong Lu

Control of an inflammatory immune response is still an ongoing research. Here, a strategy consisting of manipulating a pro and anti-inflammatory mediator is considered. Already existing and promising model-based techniques suffer…

Optimization and Control · Mathematics 2016-07-26 Ouassim Bara , Michel Fliess , Cédric Join , Judy Day , Seddik M. Djouadi

As user simulators are increasingly used for interactive training and evaluation of AI assistants, it is essential that they represent the diverse behaviors of real users. While existing works train user simulators to generate human-like…

Computation and Language · Computer Science 2026-05-11 Shuhaib Mehri , Philippe Laban , Sumuk Shashidhar , Marwa Abdulhai , Sergey Levine , Michel Galley , Dilek Hakkani-Tür

This study investigates the behaviors of Large Language Models (LLMs) when faced with conflicting prompts versus their internal memory. This will not only help to understand LLMs' decision mechanism but also benefit real-world applications,…

Computation and Language · Computer Science 2024-02-21 Jiahao Ying , Yixin Cao , Kai Xiong , Yidong He , Long Cui , Yongbin Liu

Job interviews play a critical role in shaping one's career, yet practicing interview skills can be challenging, especially without access to human coaches or peers for feedback. Recent advancements in large language models (LLMs) present…

Human-Computer Interaction · Computer Science 2024-11-05 Taufiq Daryanto , Xiaohan Ding , Lance T. Wilhelm , Sophia Stil , Kirk McInnis Knutsen , Eugenia H. Rho

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Patients are increasingly using large language models (LLMs) to seek answers to their healthcare-related questions. However, benchmarking efforts in LLMs for question answering often focus on medical exam questions, which differ…

Computation and Language · Computer Science 2026-03-19 Raymond Xiong , Furong Jia , Lionel Wong , Monica Agrawal

Large language models (LLMs) are increasingly being adopted as the cognitive core of embodied agents. However, inherited hallucinations, which stem from failures to ground user instructions in the observed physical environment, can lead to…

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large language models are thought to have the potential to aid in medical decision making. This work investigates the degree to which this might be the case. We start with the treatment problem, the patient's core medical decision-making…

Other Statistics · Statistics 2026-04-30 Samuel J. Weisenthal

In recent years, interest has arisen in using machine learning to improve the efficiency of automatic medical consultation and enhance patient experience. In this article, we propose two frameworks to support automatic medical consultation,…

Computation and Language · Computer Science 2022-12-27 Wei Chen , Zhiwei Li , Hongyi Fang , Qianyuan Yao , Cheng Zhong , Jianye Hao , Qi Zhang , Xuanjing Huang , Jiajie Peng , Zhongyu Wei

Rare disease diagnosis is inherently challenging due to heterogeneous symptoms, limited clinical familiarity, and fragmented evidence across specialties. Recent large language model (LLM)-based agentic systems have shown promise by…

Human-Computer Interaction · Computer Science 2026-03-31 Peng Kuai , Yukun Yang , Shaolun Ruan , Junchi Xu , Yanjie Zhang , Lin Zhang , Min Zhu , Rui Sheng

Large Language Models (LLMs) are powerful computational models trained on extensive corpora of human-readable text, enabling them to perform general-purpose language understanding and generation. LLMs have garnered significant attention in…

Computation and Language · Computer Science 2024-10-28 Liam Barkley , Brink van der Merwe

Large language model (LLM) systems suffer from the models' unstable ability to generate valid and factual content, resulting in hallucination generation. Current hallucination detection methods heavily rely on out-of-model information…

Computation and Language · Computer Science 2025-02-20 Peiran Wang , Yang Liu , Yunfei Lu , Jue Hong , Ye Wu

The use of Large Language Models (LLMs) for simulating user behavior in the domain of Interactive Information Retrieval has recently gained significant popularity. However, their application and capabilities remain highly debated and…

Information Retrieval · Computer Science 2025-05-07 Andreas Konstantin Kruff , Timo Breuer , Philipp Schaer

Automatic diagnosis is a significant application of AI in healthcare, where diagnoses are generated based on the symptom description of patients. Previous works have approached this task directly by modeling the relationship between the…

Computation and Language · Computer Science 2024-01-30 Haochun Wang , Sendong Zhao , Zewen Qiang , Nuwa Xi , Bing Qin , Ting Liu

In decision-making conversations, experts must navigate complex choices and make on-the-spot decisions while engaged in conversation. Although extensive historical data often exists, the real-time nature of these scenarios makes it…

Human-Computer Interaction · Computer Science 2025-07-15 Mohammad Abolnejadian , Shakiba Amirshahi , Matthew Brehmer , Anamaria Crisan
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