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Topological defects in active liquid crystals can be confined by introducing gradients of activity. Here, we examine the dynamical behavior of two defects confined by a sharp gradient of activity that separates an active circular region and…

Soft Condensed Matter · Physics 2021-06-16 Ali Mozaffari , Rui Zhang , Noe Atzin , Juan J. de Pablo

Active turbulence in dense active systems is characterized by high vorticity on a length scale that is large compared to that of individual entities. We describe the properties of active turbulence as momentum propagation is screened by…

Soft Condensed Matter · Physics 2014-12-24 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

We present a theory of active, permeating, polar gels, based on a two-fluid model. An active relative force between the gel components creates a steady-state current. We analyze its stability, while considering two polar coupling terms to…

Soft Condensed Matter · Physics 2022-08-04 Ram M. Adar , Jean-François Joanny

Recent experimental observations have suggested that topological defects can facilitate the creation of sharp features in developing embryos. Whereas these observations echo established knowledge about the interplay between geometry and…

Soft Condensed Matter · Physics 2023-07-25 Ludwig A. Hoffmann , Livio Nicola Carenza , Luca Giomi

We present a single, unified, multi-scale model to study the attachment\detachment dynamics of two deforming, near spherical cells, coated with binding ligands and subject to a slow, homogeneous shear flow in a viscous fluid medium. The…

Cell Behavior · Quantitative Biology 2015-04-23 Sarthok Sircar , Anthony J. Roberts

Cell motility in dense cell collectives is pivotal in various diseases like cancer metastasis and asthma. A central aspect in these phenomena is the heterogeneity in cell motility, but identifying the motility of individual cells is…

The cytoskeleton is an inhomogeneous network of semi-flexible filaments, which are involved in a wide variety of active biological processes. Although the cytoskeletal filaments can be very stiff and embedded in a dense and cross-linked…

Biological Physics · Physics 2019-05-24 Ines Weber , Cécile Appert-Rolland , Grégory Schehr , Ludger Santen

The study of spindle-like cells as nematic liquid crystals has led to remarkable insights in the understanding of tissue organization and morphogenesis. In the characterization of this anomalous liquid crystal material, we focus on the…

Soft Condensed Matter · Physics 2025-07-24 Aniruddh Murali , Prasoon Awasthi , Kirsten Endresen , Arkadiusz Goszczak , Francesca Serra

We present a generic framework for modelling three-dimensional deformable shells of active matter that captures the orientational dynamics of the active particles and hydrodynamic interactions on the shell and with the surrounding…

Soft Condensed Matter · Physics 2019-11-20 Luuk Metselaar , Julia M. Yeomans , Amin Doostmohammadi

The mechanical behaviour and symmetry-breaking shape deformation of red blood cells subjected to shear flows is used to demonstrate that far from being random fluids, both the membrane and cytoplasm of every biological cell undergo…

General Physics · Physics 2007-05-23 Juanita Lofthouse

The collective behavior of active semiflexible filaments is studied with a model of tangentially driven self-propelled worm-like chains. The combination of excluded-volume interactions and self-propulsion leads to several distinct dynamic…

Biological Physics · Physics 2024-06-03 Ozer Duman , Rolf E. Isele-Holder , Jens Elgeti , Gerhard Gompper

The dynamics of a nucleate cell in shear flow is of great relevance in cancer cells and circulatory tumor cells where they dominate the dynamics of blood. Buoyed by the success of Giant Unilamellar vesicles in explaining the dynamics of…

Soft Condensed Matter · Physics 2018-12-04 Kumari Priti Sinha , Rochish M Thaokar

An exact kinematic law for the motion of disclination lines in nematic liquid crystals as a function of the tensor order parameter $\mathbf{Q}$ is derived. Unlike other order parameter fields that become singular at their respective defect…

Soft Condensed Matter · Physics 2023-05-31 Cody D. Schimming , Jorge Viñals

Living cells and tissues can generate complex patterns of electric fields and fluid flows which can play important role in physiology. Both, fields and flows are rooted in ion transport across biological interfaces: cell membranes and…

Soft Condensed Matter · Physics 2026-05-22 Amit Singh Vishen , Ahandeep Manna , Frank Jülicher

A continuum description is built to characterize the stationary and transient deformations of confluent tissues subject to heterogeneous activities. By defining a coarse-grained texture matrix field to represent the shape and size of cells,…

Biological Physics · Physics 2023-08-10 Fernanda Pérez-Verdugo , Rodrigo Soto

Inspired by dense contractile tissues, where cells are subject to periodic deformation, we formulate and study a generic hydrodynamic theory of pulsating active liquids. Combining mechanical and phenomenological arguments, we postulate that…

Soft Condensed Matter · Physics 2025-09-25 Tirthankar Banerjee , Thibault Desaleux , Jonas Ranft , Étienne Fodor

Eukaryote cells have a flexible shape, which dynamically changes according to the function performed by the cell. One mechanism for deforming the cell membrane into the desired shape is through the expression of curved membrane proteins.…

Biological Physics · Physics 2018-12-05 Miha Fošnarič , Samo Penič , Aleš Iglič , Veronika Kralj-Iglič , Mitja Drab , Nir Gov

Activity can organize matter in unique configurations inaccessible to equilibrium systems, including a sundry of spiraling shapes seen in nature that range from galaxies to living tissues to fossilized stromatolites. How these dynamic yet…

Soft Condensed Matter · Physics 2023-05-23 Xingting Gong , Manu Prakash

A body immersed in a nematic liquid crystal disturbs the fluid's preferred molecular configuration and increases its stored elastic energy. In an active nematic, the fluid components also generate a stress in the bulk fluid. By introducing…

Soft Condensed Matter · Physics 2025-06-17 Thomas G. J. Chandler , Saverio E. Spagnolie

We coarse-grain a model of closely-packed ellipses that can vary their aspect ratio to derive continuum equations for materials comprising confluent deformable particles such as epithelial cell layers. We show that contractile nearest…

Soft Condensed Matter · Physics 2025-01-14 Mehrana R. Nejad , Julia M Yeomans
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