Related papers: First experimental test of a coded-mask gamma came…
The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…
In the context of range monitoring for particle therapy, this study presents the first experimental results obtained with the TIARA detector using carbon-ion beams at the CNAO clinical center in Pavia, Italy. TIARA is based on the Prompt…
The accurate imaging and quantitative measurement of 478-keV prompt gamma rays are critical for advancing boron neutron capture therapy (BNCT), a promising cancer treatment. Although numerical simulations have indicated that such…
Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…
Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…
Purpose: Handheld gamma cameras with coded aperture collimators are under investigation for intraoperative imaging in nuclear medicine. Coded apertures are a promising collimation technique for applications such as lymph node localization…
To detect and track structural changes in atomic nuclei, the systematic study of nuclear levels with firm spin-parity assignments is important. While linear polarization measurements have been applied to determine the electromagnetic…
We present an experimental setup and methodology designed to facilitate high-precision thermal measurements required for infrared medical tomography. The approach which is best suited for the study of specialized hardware phantoms comprises…
A prototype of the MeV gamma-ray imaging camera based on the full reconstruction of the Compton process has been developed. This camera consists of a micro-TPC that is a gaseous Time Projection Chamber (TPC) and scintillation cameras. With…
The use of contrast agents has previously been proposed as a novel method to increase the activation close to the Bragg peak, aiming to improve the quality of proton range monitoring in vivo. In a recent work, we demonstrated the…
Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…
Targeted Radionuclide Therapy (TRT) is a well-established technique for cancer treatment. In this approach, radionuclides are bound to specific drugs that selectively transport them to the tumor site. Within the ISOLPHARM project, a…
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments is still a matter of research. A possible technique exploits the information…
Purpose: To measure dispersion of a clinical proton therapy beam. Methods and Materials: The proton center at our institution uses a Hitachi PROBEAT V synchrotron that delivers beams with energies ranging from 70 to 230 MeV to five…
We propose an innovative method for proton radiography based on nuclear emulsion film detectors, a technique in which images are obtained by measuring the position and the residual range of protons passing through the patient's body. For…
Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…
Monitoring the dose delivered during proton and carbon ion therapy is still a matter of research. Among the possible solutions, several exploit the measurement of the single photon emission from nuclear decays induced by the irradiation. To…
In the framework of a national funded program for nuclear safety, a first prototype of portable gamma camera was built and tested. It integrates a Caliste-HD CdTe-hybrid detector designed for space X-ray astronomy coupled with a new…