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Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

Computation and Language · Computer Science 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

Several studies showed that Large Language Models (LLMs) can answer medical questions correctly, even outperforming the average human score in some medical exams. However, to our knowledge, no study has been conducted to assess the ability…

Computation and Language · Computer Science 2025-01-03 Asma Ben Abacha , Wen-wai Yim , Yujuan Fu , Zhaoyi Sun , Meliha Yetisgen , Fei Xia , Thomas Lin

Automated analysis of clinical notes is attracting increasing attention. However, there has not been much work on medical term abbreviation disambiguation. Such abbreviations are abundant, and highly ambiguous, in clinical documents. One of…

Computation and Language · Computer Science 2019-11-01 Irene Li , Michihiro Yasunaga , Muhammed Yavuz Nuzumlalı , Cesar Caraballo , Shiwani Mahajan , Harlan Krumholz , Dragomir Radev

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Clinical notes in electronic health records contain highly heterogeneous writing styles, including non-standard terminology or abbreviations. Using these notes in predictive modeling has traditionally required preprocessing (e.g. taking…

Machine Learning · Computer Science 2019-11-18 Jonas Kemp , Alvin Rajkomar , Andrew M. Dai

Electronic Health Records (EHR) store clinical documentation as base64 encoded attachments in FHIR DocumentReference resources, which makes semantic question answering difficult. Traditional vector database methods often miss nuanced…

Computation and Language · Computer Science 2025-10-31 Tarun Kumar Chawdhury , Jon D. Duke

Physician burnout in the United States has reached critical levels, driven in part by the administrative burden of Electronic Health Record (EHR) documentation and complex diagnostic codes. To relieve this strain and maintain strict patient…

Information Retrieval · Computer Science 2026-03-25 Peter Hartnett , Chung-Chi Huang , Sarah Hartnett , David Hartnett

For years, semantic interoperability standards have sought to streamline the exchange of clinical data, yet their deployment remains time-consuming, resource-intensive, and technically challenging. To address this, we introduce a…

Computation and Language · Computer Science 2025-07-08 Alvaro Riquelme , Pedro Costa , Catalina Martinez

In the medical domain, identifying and expanding abbreviations in clinical texts is a vital task for both better human and machine understanding. It is a challenging task because many abbreviations are ambiguous especially for intensive…

Computation and Language · Computer Science 2018-06-11 Yue Liu , Tao Ge , Kusum S. Mathews , Heng Ji , Deborah L. McGuinness

Clinical notes, which can be embedded into electronic medical records, document patient care delivery and summarize interactions between healthcare providers and patients. These clinical notes directly inform patient care and can also…

Computation and Language · Computer Science 2022-03-25 Suzanna Schmeelk , Martins Samuel Dogo , Yifan Peng , Braja Gopal Patra

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…

Computation and Language · Computer Science 2018-08-09 Peter J. Liu

Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed…

Computation and Language · Computer Science 2019-05-23 Oren Melamud , Chaitanya Shivade

Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated…

Computation and Language · Computer Science 2025-04-03 Charles Alba , Bing Xue , Joanna Abraham , Thomas Kannampallil , Chenyang Lu

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

Computation and Language · Computer Science 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

This study examines integrating EHRs and NLP with large language models (LLMs) to improve healthcare data management and patient care. It focuses on using advanced models to create secure, HIPAA-compliant synthetic patient notes for…

Computation and Language · Computer Science 2025-06-03 Yao-Shun Chuang , Atiquer Rahman Sarkar , Yu-Chun Hsu , Noman Mohammed , Xiaoqian Jiang

As patients' access to their doctors' clinical notes becomes common, translating professional, clinical jargon to layperson-understandable language is essential to improve patient-clinician communication. Such translation yields better…

Computation and Language · Computer Science 2019-05-28 Wei-Hung Weng , Yu-An Chung , Peter Szolovits