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Recent advances in generative modelling have led many to see synthetic data as the go-to solution for a range of problems around data access, scarcity, and under-representation. In this paper, we study three prominent use cases: (1) Sharing…

Machine Learning · Computer Science 2026-02-04 Bogdan Kulynych , Theresa Stadler , Jean Louis Raisaro , Carmela Troncoso

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

Training and fine-tuning deep learning models, especially large language models (LLMs), on limited and imbalanced datasets poses substantial challenges. These issues often result in poor generalization, where models overfit to dominant…

Computation and Language · Computer Science 2025-01-14 Ashok Choudhary , Cornelius Thiels , Hojjat Salehinejad

Collecting large amounts of real-world interaction data to train general robotic policies is often prohibitively expensive, thus motivating the use of simulation data. However, existing methods for data generation have generally focused on…

Machine Learning · Computer Science 2024-01-23 Lirui Wang , Yiyang Ling , Zhecheng Yuan , Mohit Shridhar , Chen Bao , Yuzhe Qin , Bailin Wang , Huazhe Xu , Xiaolong Wang

Large Language Models (LLMs) are increasingly used to generate synthetic textual data for training smaller specialized models. However, a comparison of various generation strategies for low-resource language settings is lacking. While…

Computation and Language · Computer Science 2025-09-22 Tatiana Anikina , Jan Cegin , Jakub Simko , Simon Ostermann

Synthetic augmentation is increasingly used to mitigate data scarcity in financial machine learning, yet its statistical role remains poorly understood. We formalize synthetic augmentation as a modification of the effective training…

Artificial Intelligence · Computer Science 2026-04-17 Mel Sohm , Charles Dezons , Sami Sellami , Oscar Ninou , Axel Pincon

Pretrained language models (PLMs), such as GPT2, have achieved remarkable empirical performance in text generation tasks. However, pretrained on large-scale natural language corpora, the generated text from PLMs may exhibit social bias…

Computation and Language · Computer Science 2023-02-28 Rui Wang , Pengyu Cheng , Ricardo Henao

Large Language Models (LLMs) excel at generating synthetic data, but ensuring its quality and diversity remains challenging. We propose Genetic Prompt, a novel framework that combines genetic algorithms with LLMs to augment synthetic data…

Computation and Language · Computer Science 2025-09-03 Guangzeng Han , Weisi Liu , Xiaolei Huang

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Tabular data is one of the most prevalent and important data formats in real-world applications such as healthcare, finance, and education. However, its effective use in machine learning is often constrained by data scarcity, privacy…

Machine Learning · Computer Science 2025-07-18 Ruxue Shi , Yili Wang , Mengnan Du , Xu Shen , Yi Chang , Xin Wang

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…

Computation and Language · Computer Science 2024-03-15 Erlend Frayling , Jake Lever , Graham McDonald

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

Simulating human profiles by instilling personas into large language models (LLMs) is rapidly transforming research in agentic behavioral simulation, LLM personalization, and human-AI alignment. However, most existing synthetic personas…

Artificial Intelligence · Computer Science 2025-12-02 Zhen Wang , Yufan Zhou , Zhongyan Luo , Lyumanshan Ye , Adam Wood , Man Yao , Saab Mansour , Luoshang Pan

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

Clinical data is fundamental to advance neurosurgical research, but access is often constrained by data availability, small sample sizes, privacy regulations, and resource-intensive preprocessing and de-identification procedures. Synthetic…

Computation and Language · Computer Science 2025-10-21 Austin A. Barr , Eddie Guo , Emre Sezgin

Lymph node metastasis (LNM) is a crucial factor in determining the initial treatment for patients with lung cancer, yet accurate preoperative diagnosis of LNM remains challenging. Recently, large language models (LLMs) have garnered…

Computation and Language · Computer Science 2024-08-16 Danqing Hu , Bing Liu , Xiaofeng Zhu , Nan Wu

Access to real-world medical data is often restricted due to privacy regulations, posing a significant barrier to the advancement of healthcare research. Synthetic data offers a promising alternative; however, generating realistic,…

Artificial Intelligence · Computer Science 2025-08-13 Arshia Ilaty , Hossein Shirazi , Hajar Homayouni

The success of Large Language Models (LLMs) is inherently linked to the availability of vast, diverse, and high-quality data for training and evaluation. However, the growth rate of high-quality data is significantly outpaced by the…

Computation and Language · Computer Science 2024-10-18 Ke Wang , Jiahui Zhu , Minjie Ren , Zeming Liu , Shiwei Li , Zongye Zhang , Chenkai Zhang , Xiaoyu Wu , Qiqi Zhan , Qingjie Liu , Yunhong Wang

Generating clinical synthetic text represents an effective solution for common clinical NLP issues like sparsity and privacy. This paper aims to conduct a systematic review on generating synthetic medical free-text by formulating…

Computation and Language · Computer Science 2025-07-25 Basel Alshaikhdeeb , Ahmed Abdelmonem Hemedan , Soumyabrata Ghosh , Irina Balaur , Venkata Satagopam

The advancement of Artificial Intelligence (AI) has created opportunities for e-learning, particularly in automated assessment systems that reduce educators' workload and provide timely feedback to students. However, developing effective…

Computers and Society · Computer Science 2025-02-11 Long Zhang , Meng Zhang , Wei Lin Wang , Yu Luo
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