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Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…

Computation and Language · Computer Science 2023-12-07 Charalambos Themistocleous , Kyrana Tsapkini , Dimitrios Kokkinakis

Cognitive and neurological impairments are very common, but only a small proportion of affected individuals are diagnosed and treated, partly because of the high costs associated with frequent screening. Detecting pre-illness stages and…

Computation and Language · Computer Science 2024-11-05 Francisco de Arriba-Pérez , Silvia García-Méndez , Javier Otero-Mosquera , Francisco J. González-Castaño

Agitation is one of the most common responsive behaviors in people living with dementia, particularly among those residing in community settings without continuous clinical supervision. Timely prediction of agitation can enable early…

Signal Processing · Electrical Eng. & Systems 2025-06-10 Ali Abedi , Charlene H. Chu , Shehroz S. Khan

Dementia, a neurodegenerative disease, alters speech patterns, creating communication barriers and raising privacy concerns. Current speech technologies, such as automatic speech transcription (ASR), struggle with dementia and atypical…

Computation and Language · Computer Science 2025-07-15 Dominika Woszczyk , Ranya Aloufi , Soteris Demetriou

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani

Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…

Machine Learning · Computer Science 2023-02-17 Shrish Pellakur , Nelly Elsayed , Zag ElSayed , Murat Ozer

Automatic Speech Recognition (ASR) is a critical component of any fully-automated speech-based dementia detection model. However, despite years of speech recognition research, little is known about the impact of ASR accuracy on dementia…

Computation and Language · Computer Science 2020-10-15 Aparna Balagopalan , Ksenia Shkaruta , Jekaterina Novikova

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

Speech signals, typically sampled at rates in the tens of thousands per second, contain redundancies, evoking inefficiencies in sequence modeling. High-dimensional speech features such as spectrograms are often used as the input for the…

Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…

Artificial Intelligence · Computer Science 2026-01-13 Shafiul Ajam Opee , Nafiz Fahad , Anik Sen , Rasel Ahmed , Fariha Jahan , Md. Kishor Morol , Md Rashedul Islam

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng

Automated discourse analysis tools based on Natural Language Processing (NLP) aiming at the diagnosis of language-impairing dementias generally extract several textual metrics of narrative transcripts. However, the absence of sentence…

Computation and Language · Computer Science 2017-08-17 Marcos Vinícius Treviso , Christopher Shulby , Sandra Maria Aluísio

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

Computation and Language · Computer Science 2019-10-02 Bahman Mirheidari , Yilin Pan , Traci Walker , Markus Reuber , Annalena Venneri , Daniel Blackburn , Heidi Christensen

Mild Cognitive Impairment (MCI) affects 12-18% of individuals over 60. MCI patients exhibit cognitive dysfunctions without significant daily functional loss. While MCI may progress to dementia, predicting this transition remains a clinical…

Machine Learning · Computer Science 2025-04-15 Gabriele Civitarese , Michele Fiori , Andrea Arighi , Daniela Galimberti , Graziana Florio , Claudio Bettini

Projected to impact 1.6 million people in the UK by 2040 and costing {\pounds}25 billion annually, dementia presents a growing challenge to society. This study, a pioneering effort to predict the translational potential of dementia research…

Machine Learning · Computer Science 2024-01-11 Matilda Beinat , Julian Beinat , Mohammed Shoaib , Jorge Gomez Magenti

Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…

Quantitative Methods · Quantitative Biology 2025-03-05 Yizong Xing , Dhita Putri Pratama , Yuke Wang , Yufan Zhang , Brian E. Chapman

Prompting large language models is a training-free method for detecting Alzheimer's disease from speech transcripts. Using the ADReSS dataset, we revisit zero-shot prompting and study few-shot prompting with a class-balanced protocol using…

Machine Learning · Computer Science 2025-09-25 Jana Sweidan , Mounim A. El-Yacoubi , Nasredine Semmar

\textbf{Objectives}: We aimed to investigate how errors from automatic speech recognition (ASR) systems affect dementia classification accuracy, specifically in the ``Cookie Theft'' picture description task. We aimed to assess whether…

Computation and Language · Computer Science 2024-01-12 Changye Li , Weizhe Xu , Trevor Cohen , Serguei Pakhomov

The early detection of suicide risk is important since it enables the intervention to prevent potential suicide attempts. This paper studies the automatic detection of suicide risk based on spontaneous speech from adolescents, and collects…

Computation and Language · Computer Science 2024-09-25 Ziyun Cui , Chang Lei , Wen Wu , Yinan Duan , Diyang Qu , Ji Wu , Runsen Chen , Chao Zhang
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