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Understanding whether large language models (LLMs) capture structured meaning requires examining how they represent concept relationships. In this work, we study three models of increasing scale: Pythia-70M, GPT-2, and Llama 3.1 8B,…

Computation and Language · Computer Science 2026-04-01 Andor Diera , Ansgar Scherp

Large language models (LLMs) show remarkable capabilities across a variety of tasks. Despite the models only seeing text in training, several recent studies suggest that LLM representations implicitly capture aspects of the underlying…

Computation and Language · Computer Science 2024-04-16 Yutaro Yamada , Yihan Bao , Andrew K. Lampinen , Jungo Kasai , Ilker Yildirim

Understanding the spatial architecture of the tumor microenvironment (TME) is critical to advance precision oncology. We present ProteinPNet, a novel framework based on prototypical part networks that discovers TME motifs from spatial…

Machine Learning · Computer Science 2025-12-03 Louis McConnell , Jieran Sun , Theo Maffei , Raphael Gottardo , Marianna Rapsomaniki

Understanding how features evolve across layers in deep neural networks is a fundamental challenge in mechanistic interpretability, particularly due to polysemanticity and feature superposition. While Sparse Autoencoders (SAEs) have been…

Machine Learning · Computer Science 2025-03-04 Nikita Balagansky , Ian Maksimov , Daniil Gavrilov

Large language models (LLMs) are increasingly trained in complex Reinforcement Learning, multi-agent environments, making it difficult to understand how behavior changes over training. Sparse Autoencoders (SAEs) have recently shown to be…

Machine Learning · Computer Science 2026-02-09 John Yan , Michael Yu , Yuqi Sun , Alexander Duffy , Tyler Marques , Matthew Lyle Olson

Translating the internal representations and computations of models into concepts that humans can understand is a key goal of interpretability. While recent dictionary learning methods such as Sparse Autoencoders (SAEs) provide a promising…

Computation and Language · Computer Science 2026-02-27 Usha Bhalla , Alex Oesterling , Claudio Mayrink Verdun , Himabindu Lakkaraju , Flavio P. Calmon

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

Contemporary large language models (LLMs), such as GPT-4 and Llama, have harnessed extensive computational power and diverse text corpora to achieve remarkable proficiency in interpreting and generating domain-specific content, including…

Machine Learning · Computer Science 2025-10-07 Tianren Zhang , Dai-Bei Yang

We present an automated approach for identifying and annotating motifs and domains in protein sequences, using pretrained Protein Language Models (PLMs) and Concept Activation Vectors (CAVs), adapted from interpretability research in…

Quantitative Methods · Quantitative Biology 2025-11-27 Ahmad Shamail , Claire D. McWhite

Understanding the internal machinations of deep Transformer-based NLP models is more crucial than ever as these models see widespread use in various domains that affect the public at large, such as industry, academia, finance, health. While…

Computation and Language · Computer Science 2026-05-13 Dan Pluth , Zachary Nicholas Houghton , Yu Zhou , Vijay K. Gurbani

Large Language Models (LLMs) achieve strong linguistic performance, yet their internal mechanisms for producing these predictions remain unclear. We investigate the hypothesis that LLMs encode representations of linguistic constraint…

Computation and Language · Computer Science 2026-05-15 Hardy , Sebastian Padó

Sparse autoencoders (SAEs) have emerged as a powerful technique for decomposing language model representations into interpretable features. Current interpretation methods infer feature semantics from activation patterns, but overlook that…

Machine Learning · Computer Science 2026-02-02 Yiting Liu , Zhi-Hong Deng

Pretrained language models (PLMs) have made significant strides in various natural language processing tasks. However, the lack of interpretability due to their ``black-box'' nature poses challenges for responsible implementation. Although…

Computation and Language · Computer Science 2023-11-10 Zhen Tan , Lu Cheng , Song Wang , Yuan Bo , Jundong Li , Huan Liu

While scaling laws have been continuously validated in large language models (LLMs) with increasing model parameters, the inherent tension between the inference demands of LLMs and the limited resources of edge devices poses a critical…

The meanings of words and phrases depend not only on where they are used (contexts) but also on who use them (writers). Pretrained language models (PLMs) are powerful tools for capturing context, but they are typically pretrained and…

Computation and Language · Computer Science 2023-09-15 Daisuke Oba , Naoki Yoshinaga , Masashi Toyoda

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

In recent years, the size of pre-trained language models (PLMs) has grown by leaps and bounds. However, efficiency issues of these large-scale PLMs limit their utilization in real-world scenarios. We present a suite of cost-effective…

Large Language Models (LLMs) play a crucial role in capturing structured semantics to enhance language understanding, improve interpretability, and reduce bias. Nevertheless, an ongoing controversy exists over the extent to which LLMs can…

Computation and Language · Computer Science 2024-05-13 Ning Cheng , Zhaohui Yan , Ziming Wang , Zhijie Li , Jiaming Yu , Zilong Zheng , Kewei Tu , Jinan Xu , Wenjuan Han

Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Biomolecules · Quantitative Biology 2025-09-15 Long-Kai Huang , Rongyi Zhu , Bing He , Jianhua Yao

Recent interpretability work on large language models (LLMs) has been increasingly dominated by a feature-discovery approach with the help of proxy modules. Then, the quality of features learned by, e.g., sparse auto-encoders (SAEs), is…

Machine Learning · Computer Science 2025-10-28 Mengyu Ye , Jun Suzuki , Tatsuro Inaba , Tatsuki Kuribayashi