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With the integration of image modality, the semantic space of multimodal large language models (MLLMs) is more complex than text-only models, making their interpretability more challenging and their alignment less stable, particularly…

Machine Learning · Computer Science 2025-06-18 Hantao Lou , Changye Li , Jiaming Ji , Yaodong Yang

Sparse autoencoders (SAEs) are now standard tools for decomposing language model activations into interpretable features, and automated interpretability pipelines routinely assign each feature a short natural-language explanation. Existing…

Machine Learning · Computer Science 2026-05-14 Jordan F. McCann

Large language models (LLMs) demonstrate remarkable multilingual capabilities without being pre-trained on specially curated multilingual parallel corpora. It remains a challenging problem to explain the underlying mechanisms by which LLMs…

Computation and Language · Computer Science 2024-06-07 Tianyi Tang , Wenyang Luo , Haoyang Huang , Dongdong Zhang , Xiaolei Wang , Xin Zhao , Furu Wei , Ji-Rong Wen

Activation steering methods in large language models (LLMs) have emerged as an effective way to perform targeted updates to enhance generated language without requiring large amounts of adaptation data. We ask whether the features…

Computation and Language · Computer Science 2025-11-05 Masha Fedzechkina , Eleonora Gualdoni , Sinead Williamson , Katherine Metcalf , Skyler Seto , Barry-John Theobald

Sparse autoencoders (SAEs) extract human-interpretable features from deep neural networks by transforming their activations into a sparse, higher dimensional latent space, and then reconstructing the activations from these latents.…

Machine Learning · Computer Science 2025-02-13 Gonçalo Paulo , Stepan Shabalin , Nora Belrose

Recent work has found that sparse autoencoders (SAEs) are an effective technique for unsupervised discovery of interpretable features in language models' (LMs) activations, by finding sparse, linear reconstructions of LM activations. We…

Machine Learning · Computer Science 2024-05-01 Senthooran Rajamanoharan , Arthur Conmy , Lewis Smith , Tom Lieberum , Vikrant Varma , János Kramár , Rohin Shah , Neel Nanda

While sparse autoencoders (SAEs) successfully extract interpretable features from language models, applying them to audio generation faces unique challenges: audio's dense nature requires compression that obscures semantic meaning, and…

Machine Learning · Computer Science 2025-10-31 Nathan Paek , Yongyi Zang , Qihui Yang , Randal Leistikow

The finetuning of Large Language Models (LLMs) has significantly advanced their instruction-following capabilities, yet the underlying computational mechanisms driving these improvements remain poorly understood. This study systematically…

Computation and Language · Computer Science 2025-05-28 Junyan Zhang , Yubo Gao , Yibo Yan , Jungang Li , Zhaorui Hou , Sicheng Tao , Shuliang Liu , Song Dai , Yonghua Hei , Junzhuo Li , Xuming Hu

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Computation and Language · Computer Science 2025-04-24 Gilchan Park , Byung-Jun Yoon , Xihaier Luo , Vanessa López-Marrero , Shinjae Yoo , Shantenu Jha

As large language models (LLMs) are increasingly deployed in real-world applications, the need to selectively remove unwanted knowledge while preserving model utility has become paramount. Recent work has explored sparse autoencoders (SAEs)…

Computation and Language · Computer Science 2026-04-28 Tomer Ashuach , Dana Arad , Aaron Mueller , Martin Tutek , Yonatan Belinkov

An end-to-end (E2E) ASR model implicitly learns a prior Internal Language Model (ILM) from the training transcripts. To fuse an external LM using Bayes posterior theory, the log likelihood produced by the ILM has to be accurately estimated…

Audio and Speech Processing · Electrical Eng. & Systems 2022-11-03 Yufei Liu , Rao Ma , Haihua Xu , Yi He , Zejun Ma , Weibin Zhang

Protein language models (PLMs) have demonstrated remarkable capabilities in learning relationships between protein sequences and functions. However, finetuning these large models requires substantial computational resources, often with…

Machine Learning · Computer Science 2025-12-09 Shuo Zhang , Jian K. Liu

Neural models have yielded state-of-the-art results in deciphering spoken language understanding (SLU) problems; however, these models require a significant amount of domain-specific labeled examples for training, which is prohibitively…

Computation and Language · Computer Science 2020-10-12 Jin Cao , Jun Wang , Wael Hamza , Kelly Vanee , Shang-Wen Li

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

Biomolecules · Quantitative Biology 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

Unlocking the next generation of biotechnology and therapeutic innovation demands overcoming the inherent complexity and resource-intensity of conventional protein engineering methods. Recent GenAI-powered computational techniques often…

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

Sparse Autoencoders (SAEs) have emerged as a useful tool for interpreting the internal representations of neural networks. However, naively optimising SAEs for reconstruction loss and sparsity results in a preference for SAEs that are…

Machine Learning · Computer Science 2024-10-16 Kola Ayonrinde , Michael T. Pearce , Lee Sharkey

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

Machine Learning · Computer Science 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

Predicting molecular properties is a critical component of drug discovery. Recent advances in deep learning, particularly Graph Neural Networks (GNNs), have enabled end-to-end learning from molecular structures, reducing reliance on manual…

Computation and Language · Computer Science 2025-09-26 Peng Zhou , Lai Hou Tim , Zhixiang Cheng , Kun Xie , Chaoyi Li , Wei Liu , Xiangxiang Zeng

Sparse dictionary learning (DL) has emerged as a powerful approach to extract semantically meaningful concepts from the internals of large language models (LLMs) trained mainly in the text domain. In this work, we explore whether DL can…

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