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Recently, self-supervised Masked Autoencoders (MAE) have attracted unprecedented attention for their impressive representation learning ability. However, the pretext task, Masked Image Modeling (MIM), reconstructs the missing local patches,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Feng Liang , Yangguang Li , Diana Marculescu

Molecular Property Prediction (MPP) plays a pivotal role across diverse domains, spanning drug discovery, material science, and environmental chemistry. Fueled by the exponential growth of chemical data and the evolution of artificial…

Machine Learning · Computer Science 2024-08-23 Tanya Liyaqat , Tanvir Ahmad , Chandni Saxena

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Existing vision-language methods typically support two languages at a time at most. In this paper, we present a modular approach which can easily be incorporated into existing vision-language methods in order to support many languages. We…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Donghyun Kim , Kuniaki Saito , Kate Saenko , Stan Sclaroff , Bryan A. Plummer

Joint image-text embedding is the bedrock for most Vision-and-Language (V+L) tasks, where multimodality inputs are simultaneously processed for joint visual and textual understanding. In this paper, we introduce UNITER, a UNiversal…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Yen-Chun Chen , Linjie Li , Licheng Yu , Ahmed El Kholy , Faisal Ahmed , Zhe Gan , Yu Cheng , Jingjing Liu

Multimodal information retrieval (MIR) faces inherent challenges due to the heterogeneity of data sources and the complexity of cross-modal alignment. While previous studies have identified modal gaps in feature spaces, a systematic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Fanheng Kong , Jingyuan Zhang , Yahui Liu , Hongzhi Zhang , Shi Feng , Xiaocui Yang , Daling Wang , Yu Tian , Victoria W. , Fuzheng Zhang , Guorui Zhou

Tabular-image multimodal learning, which integrates structured tabular data with imaging data, holds great promise for a variety of tasks, especially in medical applications. Yet, two key challenges remain: (1) the lack of a standardized,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Jiaqi Luo , Yuan Yuan , Shixin Xu

Cardiovascular disease arises from interactions between inherited risk, molecular programmes, and tissue-scale remodelling that are observed clinically through imaging. Health systems now routinely generate large volumes of cardiac MRI, CT…

Quantitative Methods · Quantitative Biology 2026-01-14 Minh H. N. Le , Tuan Vinh , Thanh-Huy Nguyen , Tao Li , Bao Quang Gia Le , Han H. Huynh , Monika Raj , Carl Yang , Min Xu , Nguyen Quoc Khanh Le

Medical multi-modal pre-training has revealed promise in computer-aided diagnosis by leveraging large-scale unlabeled datasets. However, existing methods based on masked autoencoders mainly rely on data-level reconstruction tasks, but lack…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yupei Zhang , Li Pan , Qiushi Yang , Tan Li , Zhen Chen

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

Autoregressive modeling has driven major advances in multimodal AI, yet its application to medical imaging remains constrained by the absence of a unified image tokenizer that simultaneously preserves fine-grained anatomical structures and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Chenglong Ma , Yuanfeng Ji , Jin Ye , Zilong Li , Chenhui Wang , Junzhi Ning , Wei Li , Lihao Liu , Qiushan Guo , Tianbin Li , Junjun He , Hongming Shan

Recent advances in multi-modal algorithms have driven and been driven by the increasing availability of large image-text datasets, leading to significant strides in various fields, including computational pathology. However, in most…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Jiawen Chen , Muqing Zhou , Wenrong Wu , Jinwei Zhang , Yun Li , Didong Li

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Multimodal semantic understanding often has to deal with uncertainty, which means the obtained messages tend to refer to multiple targets. Such uncertainty is problematic for our interpretation, including inter- and intra-modal uncertainty.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Yatai Ji , Junjie Wang , Yuan Gong , Lin Zhang , Yanru Zhu , Hongfa Wang , Jiaxing Zhang , Tetsuya Sakai , Yujiu Yang

Recent advancements in vision-language pre-training via contrastive learning have significantly improved performance across computer vision tasks. However, in the medical domain, obtaining multimodal data is often costly and challenging due…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Ameera Bawazir , Kebin Wu , Wenbin Li

The complexity of heterogeneous computing architectures, as well as the demand for productive and portable parallel application development, have driven the evolution of parallel programming models to become more comprehensive and complex…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-31 Anjia Wang , Xinyao Yi , Yonghong Yan

The quest for accurate prediction of drug molecule properties poses a fundamental challenge in the realm of Artificial Intelligence Drug Discovery (AIDD). An effective representation of drug molecules emerges as a pivotal component in this…

Machine Learning · Computer Science 2024-04-22 Zhuoyuan Wang , Jiacong Mi , Shan Lu , Jieyue He

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

Masked autoencoder (MAE) is a promising self-supervised pre-training technique that can improve the representation learning of a neural network without human intervention. However, applying MAE directly to volumetric medical images poses…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Jia-Xin Zhuang , Luyang Luo , Hao Chen