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Learning similarity is a key aspect in medical image analysis, particularly in recommendation systems or in uncovering the interpretation of anatomical data in images. Most existing methods learn such similarities in the embedding space…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Sukesh Adiga , Jose Dolz , Herve Lombaert

Recently neural scene representations have provided very impressive results for representing 3D scenes visually, however, their study and progress have mainly been limited to visualization of virtual models in computer graphics or scene…

Computer Vision and Pattern Recognition · Computer Science 2022-09-26 Yassine Ahmine , Arnab Dey , Andrew I. Comport

Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yupei Zhang , Xiaofei Wang , Fangliangzi Meng , Jin Tang , Chao Li

Euclidean representation learning methods have achieved promising results in image fusion tasks, which can be attributed to their clear advantages in handling with linear space. However, data collected from a realistic scene usually has a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Huan Kang , Hui Li , Tianyang Xu , Xiao-Jun Wu , Rui Wang , Chunyang Cheng , Josef Kittler

Deep learning methods have revolutionized speech recognition, image recognition, and natural language processing since 2010. Each of these tasks involves a single modality in their input signals. However, many applications in the artificial…

Artificial Intelligence · Computer Science 2020-07-15 Chao Zhang , Zichao Yang , Xiaodong He , Li Deng

We propose the Motion Capsule Autoencoder (MCAE), which addresses a key challenge in the unsupervised learning of motion representations: transformation invariance. MCAE models motion in a two-level hierarchy. In the lower level, a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Ziwei Xu , Xudong Shen , Yongkang Wong , Mohan S Kankanhalli

Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a frozen patch encoder, a projection layer, and a slide-level aggregator. While encoders and…

Quantitative Methods · Quantitative Biology 2026-05-19 Yucheng Xing , Pei Liu , Jingying Ma , Ruping Hong , Jiangdong Qiu , Tianyu Liu , Kai He , Ling Huang , Mengling Feng

User representation modeling has become increasingly crucial for personalized applications, yet existing approaches struggle with generalizability across domains and sensitivity to noisy behavioral signals. We present InstructUE, an…

Machine Learning · Computer Science 2025-10-14 Ziyi Gao , Yike Xu , Jiahao Yuan , Baokun Wang , Jinyong Wen , Xiaotong Lin , Yun Liu , Xing Fu , Yu Cheng , Yongchao Liu , Weiqiang Wang , Zhongle Xie

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

The adoption of digital systems in healthcare has resulted in the accumulation of vast electronic health records (EHRs), offering valuable data for machine learning methods to predict patient health outcomes. However, single-visit records…

Machine Learning · Computer Science 2024-11-19 Eric Yang , Pengfei Hu , Xiaoxue Han , Yue Ning

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

With the surge in available data from various modalities, there is a growing need to bridge the gap between different data types. In this work, we introduce a novel approach to learn cross-modal representations between image data and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Watkinson Gabriel , Cohen Ethan , Bourriez Nicolas , Bendidi Ihab , Bollot Guillaume , Genovesio Auguste

Multi-label image classification is a foundational topic in various domains. Multimodal learning approaches have recently achieved outstanding results in image representation and single-label image classification. For instance, Contrastive…

Computer Vision and Pattern Recognition · Computer Science 2022-11-11 Fengjun Wang , Sarai Mizrachi , Moran Beladev , Guy Nadav , Gil Amsalem , Karen Lastmann Assaraf , Hadas Harush Boker

Pre-trained encoders for offline feature extraction followed by multiple instance learning (MIL) aggregators have become the dominant paradigm in computational pathology (CPath), benefiting cancer diagnosis and prognosis. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Wenhao Tang , Rong Qin , Heng Fang , Fengtao Zhou , Hao Chen , Xiang Li , Ming-Ming Cheng

Imaging-derived phenotypes (IDPs) summarize multi-organ physiology but provide only static snapshots of diseases that evolve over time. In contrast, longitudinal electronic health records encode disease trajectories through temporal…

Information Retrieval · Computer Science 2026-05-13 Zian Wang , Lizhen Lan , Guangming Wang , Haosen Zhang , Minxuan Xu , Qing Li , Tianxing He , Mo Yang , Wenyue Mao , Yajing Zhang , Yan Li , Chengyan Wang

Identifying specific anatomical structures (\textit{e.g.}, lesions or landmarks) in medical images plays a fundamental role in medical image analysis. Exemplar-based landmark detection methods are receiving increasing attention since they…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Xiaoyu Bai , Fan Bai , Xiaofei Huo , Jia Ge , Jingjing Lu , Xianghua Ye , Ke Yan , Yong Xia

Machine learning approaches have become popular for molecular modeling tasks, including molecular force fields and properties prediction. Traditional supervised learning methods suffer from scarcity of labeled data for particular tasks,…

Chemical Physics · Physics 2022-11-29 Xiang Gao , Weihao Gao , Wenzhi Xiao , Zhirui Wang , Chong Wang , Liang Xiang

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent machine learning methods for image reconstruction typically involve supervised learning or unsupervised learning,…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Siqi Ye , Zhipeng Li , Michael T. McCann , Yong Long , Saiprasad Ravishankar

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir
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