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Recently, a noticeable trend has emerged in developing pre-trained foundation models in the domains of CV and NLP. However, for molecular pre-training, there lacks a universal model capable of effectively applying to various categories of…

Biomolecules · Quantitative Biology 2024-05-21 Shikun Feng , Yuyan Ni , Minghao Li , Yanwen Huang , Zhi-Ming Ma , Wei-Ying Ma , Yanyan Lan

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Deep learning has shown significant value in medical image registration for motion correction, however, current techniques are either limited by the type and range of motion they can handle, or require iterative inference and/or retraining…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Jian Wang , Razieh Faghihpirayesh , Danny Joca , Polina Golland , Ali Gholipour

Molecular representation learning plays an essential role in cheminformatics. Recently, language model-based approaches have gained popularity as an alternative to traditional expert-designed features to encode molecules. However, these…

Machine Learning · Computer Science 2022-04-19 Zhihui Guo , Pramod Sharma , Andy Martinez , Liang Du , Robin Abraham

The recently advanced unsupervised learning approaches use the siamese-like framework to compare two "views" from the same image for learning representations. Making the two views distinctive is a core to guarantee that unsupervised methods…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Zhiqiang Shen , Zechun Liu , Zhuang Liu , Marios Savvides , Trevor Darrell , Eric Xing

Deciphering visual content from functional Magnetic Resonance Imaging (fMRI) helps illuminate the human vision system. However, the scarcity of fMRI data and noise hamper brain decoding model performance. Previous approaches primarily…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Yulong Liu , Yongqiang Ma , Guibo Zhu , Haodong Jing , Nanning Zheng

The development of multimodal models for pulmonary nodule diagnosis is limited by the scarcity of labeled data and the tendency for these models to overfit on the training distribution. In this work, we leverage self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Thomas Z. Li , Aravind R. Krishnan , Lianrui Zuo , John M. Still , Kim L. Sandler , Fabien Maldonado , Thomas A. Lasko , Bennett A. Landman

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

We present EmbodiedMAE, a unified 3D multi-modal representation for robot manipulation. Current approaches suffer from significant domain gaps between training datasets and robot manipulation tasks, while also lacking model architectures…

Robotics · Computer Science 2025-05-16 Zibin Dong , Fei Ni , Yifu Yuan , Yinchuan Li , Jianye Hao

The success of deep neural networks for pan-sharpening is commonly in a form of black box, lacking transparency and interpretability. To alleviate this issue, we propose a novel model-driven deep unfolding framework with image reasoning…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Man Zhou , Jie Huang , Naishan Zheng , Chongyi Li

The fine-grained surface reconstruction of different organs from 3D medical imaging can provide advanced diagnostic support and improved surgical planning. However, the representation of the organs is often limited by the resolution, with a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Farahdiba Zarin , Nicolas Padoy , Jérémy Dana , Vinkle Srivastav

Contrastive learning based vision-language joint pre-training has emerged as a successful representation learning strategy. In this paper, we present a prototype representation learning framework incorporating both global and local…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Pujin Cheng , Li Lin , Junyan Lyu , Yijin Huang , Wenhan Luo , Xiaoying Tang

While embeddings from multimodal large language models (LLMs) excel as general-purpose representations, their application to dynamic modalities like audio and video remains underexplored. We introduce WAVE (\textbf{u}nified \&…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Changli Tang , Qinfan Xiao , Ke Mei , Tianyi Wang , Fengyun Rao , Chao Zhang

Learning medical visual representations from image-report pairs through joint learning has garnered increasing research attention due to its potential to alleviate the data scarcity problem in the medical domain. The primary challenges stem…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jun Wang , Lixing Zhu , Xiaohan Yu , Abhir Bhalerao , Yulan He

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

Machine Learning · Computer Science 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

In complex visual recognition tasks it is typical to adopt multiple descriptors, that describe different aspects of the images, for obtaining an improved recognition performance. Descriptors that have diverse forms can be fused into a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-15 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Andreas Spanias

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Shaohao Rui , Lingzhi Chen , Zhenyu Tang , Lilong Wang , Mianxin Liu , Shaoting Zhang , Xiaosong Wang

Contrastive Language-Image Pre-training (CLIP) has shown impressive performance in aligning visual and textual representations. Recent studies have extended this paradigm to 3D vision to improve scene understanding for autonomous driving. A…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Ximeng Tao , Dimitar Filev , Gaurav Pandey