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This study compares the efficacy of GPT-4 and clinalytix Medical AI in predicting the clinical risk of delirium development. Findings indicate that GPT-4 exhibited significant deficiencies in identifying positive cases and struggled to…

Computation and Language · Computer Science 2024-09-17 Mohamed Rezk , Patricia Cabanillas Silva , Fried-Michael Dahlweid

Clinical trial outcome prediction seeks to estimate the likelihood that a clinical trial will successfully reach its intended endpoint. This process predominantly involves the development of machine learning models that utilize a variety of…

Biomolecules · Quantitative Biology 2024-05-14 Chufan Gao , Tianfan Fu , Jimeng Sun

Prognosis prediction is crucial for determining optimal treatment plans for lung cancer patients. Traditionally, such predictions relied on models developed from retrospective patient data. Recently, large language models (LLMs) have gained…

Computation and Language · Computer Science 2024-08-16 Danqing Hu , Bing Liu , Xiang Li , Xiaofeng Zhu , Nan Wu

Lymph node metastasis (LNM) is a crucial factor in determining the initial treatment for patients with lung cancer, yet accurate preoperative diagnosis of LNM remains challenging. Recently, large language models (LLMs) have garnered…

Computation and Language · Computer Science 2024-08-16 Danqing Hu , Bing Liu , Xiaofeng Zhu , Nan Wu

The recent swift development of LLMs like GPT-4, Gemini, and GPT-3.5 offers a transformative opportunity in medicine and healthcare, especially in digital diagnostics. This study evaluates each model diagnostic abilities by interpreting a…

Computation and Language · Computer Science 2024-05-14 Gaurav Kumar Gupta , Aditi Singh , Sijo Valayakkad Manikandan , Abul Ehtesham

Large language models (LLMs) achieve high accuracy in medical diagnosis when all clinical information is provided in a single turn, yet how they behave under multi-turn evidence accumulation closer to real clinical reasoning remains…

Computation and Language · Computer Science 2026-04-07 Jinrui Fang , Runhan Chen , Xu Yang , Jian Yu , Jiawei Xu , Ashwin Vinod , Wenqi Shi , Tianlong Chen , Heng Ji , ChengXiang Zhai , Ying Ding , Yuji Zhang

We investigate the presence of cognitive biases in three large language models (LLMs): GPT-4o, Gemma 2, and Llama 3.1. The study uses 1,500 experiments across nine established cognitive biases to evaluate the models' responses and…

Artificial Intelligence · Computer Science 2025-09-11 Payam Saeedi , Mahsa Goodarzi , M Abdullah Canbaz

To solve complex tasks, large language models (LLMs) often require multiple rounds of interactions with the user, sometimes assisted by external tools. However, current evaluation protocols often emphasize benchmark performance with…

Computation and Language · Computer Science 2024-03-13 Xingyao Wang , Zihan Wang , Jiateng Liu , Yangyi Chen , Lifan Yuan , Hao Peng , Heng Ji

Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including…

Computation and Language · Computer Science 2023-11-15 Xinyu Gong , Jason Holmes , Yiwei Li , Zhengliang Liu , Qi Gan , Zihao Wu , Jianli Zhang , Yusong Zou , Yuxi Teng , Tian Jiang , Hongtu Zhu , Wei Liu , Tianming Liu , Yajun Yan

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Computation and Language · Computer Science 2025-02-14 Lena Schmidt , Kaitlyn Hair , Sergio Graziosi , Fiona Campbell , Claudia Kapp , Alireza Khanteymoori , Dawn Craig , Mark Engelbert , James Thomas

This study investigates the efficacy of large language models (LLMs) as tools for grading master-level student essays. Utilizing a sample of 60 essays in political science, the study compares the accuracy of grades suggested by the GPT-4…

General Economics · Economics 2024-06-25 Magnus Lundgren

Intelligent Tutoring Systems (ITSs) have significantly enhanced adult literacy training, a key factor for societal participation, employment opportunities, and lifelong learning. Our study investigates the application of advanced AI models,…

Computers and Society · Computer Science 2024-03-25 Liang Zhang , Jionghao Lin , Conrad Borchers , John Sabatini , John Hollander , Meng Cao , Xiangen Hu

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Large language models (LLMs) can extract information from veterinary electronic health records (EHRs), but performance differences between models, the effect of temperature settings, and the influence of text ambiguity have not been…

Large Language Models (LLMs) have shown impressive performance on a range of educational tasks, but are still understudied for their potential to solve mathematical problems. In this study, we compare three prominent LLMs, including GPT-4o,…

Artificial Intelligence · Computer Science 2025-07-01 Ruonan Wang , Runxi Wang , Yunwen Shen , Chengfeng Wu , Qinglin Zhou , Rohitash Chandra

Large Language Models (LLMs) like GPT-4 and Gemini have significantly advanced artificial intelligence by enabling machines to generate and comprehend human-like text. Despite their impressive capabilities, LLMs are not immune to…

Computation and Language · Computer Science 2024-12-19 Jiaxu Lou , Yifan Sun

Large Language Models (LLMs) are demonstrating remarkable human like capabilities across diverse domains, including psychological assessment. This study evaluates whether LLMs, specifically GPT-4o and GPT-4o mini, can infer Big Five…

Computation and Language · Computer Science 2025-01-14 Jianfeng Zhu , Ruoming Jin , Karin G. Coifman

The rapid evolution of LLMs represents an impactful paradigm shift in digital interaction and content engagement. While they encode vast amounts of human-generated knowledge and excel in processing diverse data types, they often face the…

Human-Computer Interaction · Computer Science 2024-11-20 Anna Bodonhelyi , Efe Bozkir , Shuo Yang , Enkelejda Kasneci , Gjergji Kasneci

This paper presents an in-depth analysis of the performance of seven different Large Language Models (LLMs) in solving a diverse set of math advanced calculus problems. The study aims to evaluate these models' accuracy, reliability, and…

Computation and Language · Computer Science 2025-03-07 In Hak Moon

Large language models (LLMs) are currently at the forefront of intertwining AI systems with human communication and everyday life. Therefore, it is of great importance to evaluate their emerging abilities. In this study, we show that LLMs…

Computation and Language · Computer Science 2023-10-10 Thilo Hagendorff , Sarah Fabi , Michal Kosinski
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