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Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical…

Computation and Language · Computer Science 2023-11-10 Jason Holmes , Shuyuan Ye , Yiwei Li , Shi-Nan Wu , Zhengliang Liu , Zihao Wu , Jinyu Hu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

Cognitive psychology delves on understanding perception, attention, memory, language, problem-solving, decision-making, and reasoning. Large language models (LLMs) are emerging as potent tools increasingly capable of performing human-level…

Computation and Language · Computer Science 2023-04-13 Sifatkaur Dhingra , Manmeet Singh , Vaisakh SB , Neetiraj Malviya , Sukhpal Singh Gill

Thanks to the rapidly evolving integration of LLMs into decision-support tools, a significant transformation is happening across large-scale systems. Like other medical fields, the use of LLMs such as GPT-4 is gaining increasing interest in…

Introduction: Large language models (LLM) have shown great potential in clinical decision support. GPT-5 is a novel LLM system that has been specifically marketed towards oncology use. Methods: Performance was assessed using two…

As educational systems evolve, ensuring that assessment items remain aligned with content standards is essential for maintaining fairness and instructional relevance. Traditional human alignment reviews are accurate but slow and…

Artificial Intelligence · Computer Science 2025-11-26 Farzan Karimi-Malekabadi , Pooya Razavi , Sonya Powers

Large Language Models (LLMs) have demonstrated impressive capabilities in natural language and code generation, and are increasingly deployed as automatic judges of model outputs and learning activities. Yet, their behavior on structured…

Computation and Language · Computer Science 2025-11-25 H. M. Shadman Tabib , Jaber Ahmed Deedar

This study explores the potential of Large Language Models (LLMs), specifically GPT-4, to enhance objectivity in organizational task performance evaluations. Through comparative analyses across two studies, including various task…

Computation and Language · Computer Science 2024-08-13 Ning Li , Huaikang Zhou , Mingze Xu

The rapid evolution of artificial intelligence (AI), especially in the domain of Large Language Models (LLMs) and generative AI, has opened new avenues for application across various fields, yet its role in business education remains…

Computation and Language · Computer Science 2024-01-09 Vahid Ashrafimoghari , Necdet Gürkan , Jordan W. Suchow

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

Computation and Language · Computer Science 2025-12-30 Mengdi Chai , Ali R. Zomorrodi

Although supervised machine learning is popular for information extraction from clinical notes, creating large annotated datasets requires extensive domain expertise and is time-consuming. Meanwhile, large language models (LLMs) have…

Computation and Language · Computer Science 2024-01-26 Madhumita Sushil , Travis Zack , Divneet Mandair , Zhiwei Zheng , Ahmed Wali , Yan-Ning Yu , Yuwei Quan , Atul J. Butte

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Large language models (LLMs) have made rapid improvement on medical benchmarks, but their unreliability remains a persistent challenge for safe real-world uses. To design for the use LLMs as a category, rather than for specific models,…

Computation and Language · Computer Science 2024-10-14 Andrew M. Bean , Karolina Korgul , Felix Krones , Robert McCraith , Adam Mahdi

Large Language Models (LLM) have recently been shown to perform well at various tasks from language understanding, reasoning, storytelling, and information search to theory of mind. In an extension of this work, we explore the ability of…

Computation and Language · Computer Science 2023-10-31 Nutchanon Yongsatianchot , Tobias Thejll-Madsen , Stacy Marsella

Clinical trials are crucial for drug development but are time consuming, expensive, and often burdensome on patients. More importantly, clinical trials face uncertain outcomes due to issues with efficacy, safety, or problems with patient…

Computers and Society · Computer Science 2022-03-15 Tianfan Fu , Kexin Huang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Large language models (LLMs) have made significant advancements in natural language processing (NLP). Broad corpora capture diverse patterns but can introduce irrelevance, while focused corpora enhance reliability by reducing misleading…

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

In this study, we investigate the capabilities and inherent biases of advanced large language models (LLMs) such as GPT-3.5 and GPT-4 in the context of debate evaluation. We discover that LLM's performance exceeds humans and surpasses the…

Computation and Language · Computer Science 2024-06-05 Xinyi Liu , Pinxin Liu , Hangfeng He

Purpose: Large language models (LLMs) have proven performance for certain diagnostic tasks, however limited studies have evaluated their consistency in recommending appropriate medication regimens for a given diagnosis. Medication…

Effective physician-patient communications in pre-diagnostic environments, and most specifically in complex and sensitive medical areas such as infertility, are critical but consume a lot of time and, therefore, cause clinic workflows to…

Computation and Language · Computer Science 2025-04-02 Dou Liu , Ying Long , Sophia Zuoqiu , Tian Tang , Rong Yin

Systematic reviews are vital for guiding practice, research, and policy, yet they are often slow and labour-intensive. Large language models (LLMs) could offer a way to speed up and automate systematic reviews, but their performance in such…

Computation and Language · Computer Science 2024-04-11 Qusai Khraisha , Sophie Put , Johanna Kappenberg , Azza Warraitch , Kristin Hadfield