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The success of large pre-trained object detectors hinges on their adaptability to diverse downstream tasks. While fine-tuning is the standard adaptation method, specializing these models for challenging fine-grained domains necessitates…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Vishal Gandhi , Sagar Gandhi

Pre-training on a source task is usually expected to facilitate fine-tuning on similar downstream problems. In this work, we mathematically show that this naive intuition is not always true: excessive pre-training can computationally slow…

Machine Learning · Computer Science 2026-05-28 Gibbs Nwemadji , Bruno Loureiro , Jean Barbier

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

X-ray imaging is pivotal in medical diagnostics, offering non-invasive insights into a range of health conditions. Recently, vision-language models, such as the Contrastive Language-Image Pretraining (CLIP) model, have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Xiangyu Sun , Xiaoguang Zou , Yuanquan Wu , Guotai Wang , Shaoting Zhang

The Cancer Genome Atlas (TCGA) has enabled novel discoveries and served as a large-scale reference dataset in cancer through its harmonized genomics, clinical, and imaging data. Numerous prior studies have developed bespoke deep learning…

Machine Learning · Computer Science 2026-05-11 Steven Song , Morgan Borjigin-Wang , Irene Madejski , Robert L. Grossman

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Deep metric learning aims to learn a function mapping image pixels to embedding feature vectors that model the similarity between images. Two major applications of metric learning are content-based image retrieval and face verification. For…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Andrew Zhai , Hao-Yu Wu

Cervical cancer is one of the most deadly and common diseases among women worldwide. It is completely curable if diagnosed in an early stage, but the tedious and costly detection procedure makes it unviable to conduct population-wise…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Hritam Basak , Rohit Kundu , Sukanta Chakraborty , Nibaran Das

Analyzing and inspecting bone marrow cell cytomorphology is a critical but highly complex and time-consuming component of hematopathology diagnosis. Recent advancements in artificial intelligence have paved the way for the application of…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Shayan Fazeli , Alireza Samiei , Thomas D. Lee , Majid Sarrafzadeh

In this paper, we introduce Symmetric Low-Rank Adapters, an optimized variant of LoRA with even fewer weights. This method utilizes Low-Rank Symmetric Weight Matrices to learn downstream tasks more efficiently. Traditional LoRA accumulates…

Machine Learning · Computer Science 2025-04-17 Tales Panoutsos , Rodrygo L. T. Santos , Flavio Figueiredo

Training and fine-tuning large language models (LLMs) come with challenges related to memory and computational requirements due to the increasing size of the model weights and the optimizer states. Various techniques have been developed to…

Machine Learning · Computer Science 2025-12-09 Yehonathan Refael , Jonathan Svirsky , Boris Shustin , Wasim Huleihel , Ofir Lindenbaum

The machine learning community has witnessed impressive advancements since large language models (LLMs) first appeared. Yet, their massive memory consumption has become a significant roadblock to large-scale training. For instance, a 7B…

Machine Learning · Computer Science 2024-12-30 Rui Pan , Xiang Liu , Shizhe Diao , Renjie Pi , Jipeng Zhang , Chi Han , Tong Zhang

Processing information locked within clinical health records is a challenging task that remains an active area of research in biomedical NLP. In this work, we evaluate a broad set of machine learning techniques ranging from simple RNNs to…

Adapting deep learning models to new domains often requires computationally intensive retraining and risks catastrophic forgetting. While fine-tuning enables domain-specific adaptation, it can reduce robustness to distribution shifts,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Reza Akbarian Bafghi , Carden Bagwell , Avinash Ravichandran , Ashish Shrivastava , Maziar Raissi

Foundation models in medical imaging have shown promising label efficiency, achieving high performance on downstream tasks using only a fraction of the annotated data otherwise required. In this study, we evaluate this potential in the…

Fine-tuning large-scale pre-trained models is inherently a resource-intensive task. While it can enhance the capabilities of the model, it also incurs substantial computational costs, posing challenges to the practical application of…

Computation and Language · Computer Science 2024-06-27 Yulong Mao , Kaiyu Huang , Changhao Guan , Ganglin Bao , Fengran Mo , Jinan Xu

Low-Rank Adaptation (LoRA) is a crucial method for efficiently fine-tuning large language models (LLMs), with its effectiveness influenced by two key factors: rank selection and weight initialization. While numerous LoRA variants have been…

Machine Learning · Computer Science 2025-10-27 Haonan He , Peng Ye , Yuchen Ren , Yuan Yuan , Luyang Zhou , Shucun Ju , Lei Chen

Adapters and Low-Rank Adaptation (LoRA) are parameter-efficient fine-tuning techniques designed to make the training of language models more efficient. Previous results demonstrated that these methods can even improve performance on some…

Computation and Language · Computer Science 2024-04-09 Olesya Razuvayevskaya , Ben Wu , Joao A. Leite , Freddy Heppell , Ivan Srba , Carolina Scarton , Kalina Bontcheva , Xingyi Song

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Large Language Models (LLMs) have transformed both everyday life and scientific research. However, adapting LLMs from general-purpose models to specialized tasks remains challenging, particularly in resource-constrained environments.…

Machine Learning · Computer Science 2025-09-12 Hao Zhang , Bo Huang , Zhenjia Li , Xi Xiao , Hui Yi Leong , Zumeng Zhang , Xinwei Long , Tianyang Wang , Hao Xu