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Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Fine-tuning large-scale pre-trained models is prohibitively expensive in terms of computation and memory costs. Low-Rank Adaptation (LoRA), a popular Parameter-Efficient Fine-Tuning (PEFT) method, offers an efficient solution by optimizing…

Machine Learning · Computer Science 2025-05-27 Tao Li , Zhengbao He , Yujun Li , Yasheng Wang , Lifeng Shang , Xiaolin Huang

In medical contexts, the imbalanced data distribution in long-tailed datasets, due to scarce labels for rare diseases, greatly impairs the diagnostic accuracy of deep learning models. Recent multimodal text-image supervised foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Sirui Li , Li Lin , Yijin Huang , Pujin Cheng , Xiaoying Tang

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

Large-scale multimodal foundation models, particularly Contrastive Captioners (CoCa), have achieved state-of-the-art results by unifying contrastive alignment with generative captioning. While zero-shot transfer capabilities are…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 N. K. B. M. P. K. B. Narasinghe , Uthayasanker Thayasivam

We study the computational limits of Low-Rank Adaptation (LoRA) for finetuning transformer-based models using fine-grained complexity theory. Our key observation is that the existence of low-rank decompositions within the gradient…

Machine Learning · Computer Science 2025-06-09 Jerry Yao-Chieh Hu , Maojiang Su , En-Jui Kuo , Zhao Song , Han Liu

Due to the limited availability of data, existing few-shot learning methods trained from scratch fail to achieve satisfactory performance. In contrast, large-scale pre-trained models such as CLIP demonstrate remarkable few-shot and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Kun Song , Huimin Ma , Bochao Zou , Huishuai Zhang , Weiran Huang

Accurate lung tumor segmentation is crucial for improving diagnosis, treatment planning, and patient outcomes in oncology. However, the complexity of tumor morphology, size, and location poses significant challenges for automated…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Elena Mulero Ayllón , Massimiliano Mantegna , Linlin Shen , Paolo Soda , Valerio Guarrasi , Matteo Tortora

Conventional Low-Rank Adaptation (LoRA) methods employ a fixed rank, imposing uniform adaptation across transformer layers and attention heads despite their heterogeneous learning dynamics. This paper introduces Adaptive Rank Dynamic LoRA…

Machine Learning · Computer Science 2025-12-19 Haseeb Ullah Khan Shinwari , Muhammad Usama

Computational cytology is a critical, rapid-developing, yet challenging topic in the field of medical image computing which analyzes the digitized cytology image by computer-aided technologies for cancer screening. Recently, an increasing…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Hao Jiang , Yanning Zhou , Yi Lin , Ronald CK Chan , Jiang Liu , Hao Chen

Parameter-efficient fine-tuning (PEFT) that was initially developed for exploiting pre-trained large language models has recently emerged as an effective approach to perform transfer learning on computer vision tasks. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Chenyu Lian , Hong-Yu Zhou , Yizhou Yu , Liansheng Wang

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Finetuning can be used to tackle domain-specific tasks by transferring knowledge. Previous studies on finetuning focused on adapting only the weights of a task-specific classifier or re-optimizing all layers of the pre-trained model using…

Machine Learning · Computer Science 2023-01-18 Basel Barakat , Qiang Huang

Fine-tuning has become a popular approach to adapting large foundational models to specific tasks. As the size of models and datasets grows, parameter-efficient fine-tuning techniques are increasingly important. One of the most widely used…

Histopathology is essential for disease diagnosis and treatment decision-making. Recent advances in artificial intelligence (AI) have enabled the development of pathology foundation models that learn rich visual representations from…

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological…

Artificial Intelligence · Computer Science 2025-10-01 Shangqi Gao , Sihan Wang , Yibo Gao , Boming Wang , Xiahai Zhuang , Anne Warren , Grant Stewart , James Jones , Mireia Crispin-Ortuzar

Fine-tuning large language models (LLMs) aims to adapt pre-trained models to specific tasks using relatively small and domain-specific datasets. Among Parameter-Efficient Fine-Tuning (PEFT) methods, Low-Rank Adaptation (LoRA) stands out by…

Computation and Language · Computer Science 2026-04-16 Yarui Cao , Kai Liu

Low-Rank Adapters (LoRAs) have transformed the fine-tuning of Large Language Models (LLMs) by enabling parameter-efficient updates. However, their widespread adoption remains limited by the reliance on GPU-based training. In this work, we…

Machine Learning · Computer Science 2025-07-03 Reza Arabpour , Haitz Sáez de Ocáriz Borde , Anastasis Kratsios

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas
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