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Related papers: Exploring Foundation Models Fine-Tuning for Cytolo…

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The performance of deep learning models is known to scale with data quantity and diversity. In pathology, as in many other medical imaging domains, the availability of labeled images for a specific task is often limited. Self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jonas Ammeling , Jonathan Ganz , Emely Rosbach , Ludwig Lausser , Christof A. Bertram , Katharina Breininger , Marc Aubreville

Despite recent advancements in the field of medical image analysis with the use of pretrained foundation models, the issue of distribution shifts between cross-source images largely remains adamant. To circumvent that issue, investigators…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Sanjaya Poudel , Nikita Kunwor , Raj Simkhada , Mustafa Munir , Manish Dhakal , Khem Poudel

In computational pathology, several foundation models have recently emerged and demonstrated enhanced learning capability for analyzing pathology images. However, adapting these models to various downstream tasks remains challenging,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Jeaung Lee , Jeewoo Lim , Keunho Byeon , Jin Tae Kwak

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Foundation models have become prominent in computer vision, achieving notable success in various tasks. However, their effectiveness largely depends on pre-training with extensive datasets. Applying foundation models directly to small…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Bowen Zhang , Ying Chen , Long Bai , Yan Zhao , Yuxiang Sun , Yixuan Yuan , Jianhua Zhang , Hongliang Ren

The rapid advancement of foundation modelslarge-scale neural networks trained on diverse, extensive datasetshas revolutionized artificial intelligence, enabling unprecedented advancements across domains such as natural language processing,…

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Vedrana Ivezić , Ashwath Radhachandran , Ekaterina Redekop , Shreeram Athreya , Dongwoo Lee , Vivek Sant , Corey Arnold , William Speier

To handle the large scale of whole slide images in computational pathology, most approaches first tessellate the images into smaller patches, extract features from these patches, and finally aggregate the feature vectors with…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Benedikt Roth , Valentin Koch , Sophia J. Wagner , Julia A. Schnabel , Carsten Marr , Tingying Peng

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Fine-tuning has proven to be highly effective in adapting pre-trained models to perform better on new desired tasks with minimal data samples. Among the most widely used approaches are reparameterization methods, which update a target…

Machine Learning · Computer Science 2025-10-27 Aymane El Firdoussi , El Mahdi Chayti , Mohamed El Amine Seddik , Martin Jaggi

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Foundation models open up new possibilities for the use of AI in healthcare. However, even when pre-trained on health data, they still need to be fine-tuned for specific downstream tasks. Furthermore, although foundation models reduce the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Adam Tupper , Christian Gagné

Foundation models pre-trained on large-scale datasets demonstrate strong transfer learning capabilities; however, their adaptation to complex multi-label diagnostic tasks-such as comprehensive head CT finding detection-remains understudied.…

Bone marrow cell cytomorphology analysis is critical for the diagnosis of hematological malignancies but remains a labor-intensive process subject to significant inter-observer variability. While recent foundation models have shown promise…

Other Quantitative Biology · Quantitative Biology 2025-12-23 Aziz Muminov , Anne Pham

Pre-training Large Language Models (LLMs) on web-scale datasets becomes fundamental for advancing general-purpose AI. In contrast, enhancing their predictive performance on downstream tasks typically involves adapting their knowledge…

Effectively leveraging private datasets remains a significant challenge in developing foundation models. Federated Learning (FL) has recently emerged as a collaborative framework that enables multiple users to fine-tune these models while…

Machine Learning · Computer Science 2025-10-27 Yiyuan Yang , Guodong Long , Qinghua Lu , Liming Zhu , Jing Jiang , Chengqi Zhang

Foundation models like CLIP allow zero-shot transfer on various tasks without additional training data. Yet, the zero-shot performance is less competitive than a fully supervised one. Thus, to enhance the performance, fine-tuning and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Beier Zhu , Kaihua Tang , Qianru Sun , Hanwang Zhang

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

Fine-tuning adapts a pre-trained model to downstream tasks using a small amount of labeled data. Low-Rank Adaptation (LoRA) is an efficient fine-tuning method that reduces memory and computation costs while often achieving performance close…

Machine Learning · Computer Science 2026-05-20 Ali Zindari , Rotem Mulayoff , Sebastian U. Stich
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