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Going beyond mimicking limited human experiences, recent studies show initial evidence that, like humans, large language models (LLMs) are capable of improving their abilities purely by self-correction, i.e., correcting previous responses…

Machine Learning · Computer Science 2024-11-19 Yifei Wang , Yuyang Wu , Zeming Wei , Stefanie Jegelka , Yisen Wang

Virtual Labs offer valuable opportunities for hands-on, inquiry-based science learning, yet teachers often struggle to adapt them to fit their instructional goals. Third-party materials may not align with classroom needs, and developing…

Computation and Language · Computer Science 2025-10-09 R. Alexander Knipper , Indrani Dey , Souvika Sarkar , Hari Narayanan , Sadhana Puntambekar , Santu Karmaker

Large Language Models (LLMs) have demonstrated remarkable generalization capabilities across tasks and languages, revolutionizing natural language processing. This paper investigates the naturally emerging representation alignment in LLMs,…

As Large Language Models (LLMs) are increasingly adopted in edge intelligence to power domain-specific applications and personalized services, the quality and efficiency of the LLM post-training phase-including fine-tuning and inference,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-19 Shaoyuan Huang , Yunfeng Zhao , Na Yan , Tiancheng Zhang , Xiaokai Wang , Xiaofei Wang , Wenyu Wang , Yansha Deng

Artificial intelligence has demonstrated immense potential in scientific research. Within molecular science, it is revolutionizing the traditional computer-aided paradigm, ushering in a new era of deep learning. With recent progress in…

Biomolecules · Quantitative Biology 2024-03-22 Yi Xiao , Xiangxin Zhou , Qiang Liu , Liang Wang

Large Language Models (LLMs) excel in various natural language processing tasks, but leveraging them for dense passage embedding remains challenging. This is due to their causal attention mechanism and the misalignment between their…

Computation and Language · Computer Science 2024-08-08 Hieu Man , Nghia Trung Ngo , Franck Dernoncourt , Thien Huu Nguyen

Recent advances in molecular science have been propelled significantly by large language models (LLMs). However, their effectiveness is limited when relying solely on molecular sequences, which fail to capture the complex structures of…

Quantitative Methods · Quantitative Biology 2025-08-12 Jianting Tang , Yubo Wang , Haoyu Cao , Linli Xu

Generating long, coherent text remains a challenge for large language models (LLMs), as they lack hierarchical planning and structured organization in discourse generation. We introduce Structural Alignment, a novel method that aligns LLMs…

Computation and Language · Computer Science 2026-02-04 Zae Myung Kim , Anand Ramachandran , Farideh Tavazoee , Joo-Kyung Kim , Oleg Rokhlenko , Dongyeop Kang

Visual Language Models (VLMs) are now increasingly being merged with Large Language Models (LLMs) to enable new capabilities, particularly in terms of improved interactivity and open-ended responsiveness. While these are remarkable…

Large Multimodal Models (LMMs) have achieved significant progress by extending large language models. Building on this progress, the latest developments in LMMs demonstrate the ability to generate dense pixel-wise segmentation through the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Li Zhou , Xu Yuan , Zenghui Sun , Zikun Zhou , Jingsong Lan

Recent years have witnessed remarkable progress made in large language models (LLMs). Such advancements, while garnering significant attention, have concurrently elicited various concerns. The potential of these models is undeniably vast;…

Computation and Language · Computer Science 2023-09-27 Tianhao Shen , Renren Jin , Yufei Huang , Chuang Liu , Weilong Dong , Zishan Guo , Xinwei Wu , Yan Liu , Deyi Xiong

Multi-modal Large Language Models (MLLMs) have shown remarkable capabilities in various multi-modal tasks. Nevertheless, their performance in fine-grained image understanding tasks is still limited. To address this issue, this paper…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Shiyu Xuan , Qingpei Guo , Ming Yang , Shiliang Zhang

Aligning visual features with language embeddings is a key challenge in vision-language models (VLMs). The performance of such models hinges on having a good connector that maps visual features generated by a vision encoder to a shared…

Large Language Models (LLMs) and Vision Language Models (VLMs) have recently shown promising capabilities in various scientific domain. In particular, these advances have opened new opportunities in drug discovery, where the ability to…

Artificial Intelligence · Computer Science 2026-05-13 Jueon Park , Wonjune Jang , Jiwoo Lee , Yein Park , Jaewoo Kang

In recent years, large language models (LLMs) have transformed natural language understanding through vast datasets and large-scale parameterization. Inspired by this success, we present SpecCLIP, a foundation model framework that extends…

Instrumentation and Methods for Astrophysics · Physics 2025-12-22 Xiaosheng Zhao , Yang Huang , Guirong Xue , Xiao Kong , Jifeng Liu , Xiaoyu Tang , Timothy C. Beers , Yuan-Sen Ting , A-Li Luo

Large Language Models (LLMs) have demonstrated remarkable generalization and instruction-following capabilities with instruction tuning. The advancements in LLMs and instruction tuning have led to the development of Large Vision-Language…

Machine Learning · Computer Science 2024-11-05 Jinyoung Park , Minseong Bae , Dohwan Ko , Hyunwoo J. Kim

Extending large language models to effectively handle long contexts requires instruction fine-tuning on input sequences of similar length. To address this, we present LongAlign -- a recipe of the instruction data, training, and evaluation…

Computation and Language · Computer Science 2024-02-01 Yushi Bai , Xin Lv , Jiajie Zhang , Yuze He , Ji Qi , Lei Hou , Jie Tang , Yuxiao Dong , Juanzi Li

Large language models (LLMs) are deep learning algorithms being used to perform natural language processing tasks in various fields, from social sciences to finance and biomedical sciences. Developing and training a new LLM can be very…

General Finance · Quantitative Finance 2024-01-23 Valentina Aparicio , Daniel Gordon , Sebastian G. Huayamares , Yuhuai Luo

Multilingual large language models (LLMs) possess impressive multilingual understanding and generation capabilities. However, their performance and cross-lingual alignment often lag for non-dominant languages. A common solution is to…

Computation and Language · Computer Science 2025-09-30 Mengyu Bu , Shaolei Zhang , Zhongjun He , Hua Wu , Yang Feng

Chemical representation learning has gained increasing interest due to the limited availability of supervised data in fields such as drug and materials design. This interest particularly extends to chemical language representation learning,…

Chemical Physics · Physics 2024-08-06 Jun-Hyung Park , Yeachan Kim , Mingyu Lee , Hyuntae Park , SangKeun Lee