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Large vision-language models (LVLMs) have demonstrated exceptional capabilities in understanding visual information with human languages but also exhibit an imbalance in multilingual capabilities. In this work, we delve into the…

Computation and Language · Computer Science 2025-08-27 Yuchun Fan , Yilin Wang , Yongyu Mu , Lei Huang , Bei Li , Xiaocheng Feng , Tong Xiao , Jingbo Zhu

Bridging biomolecular modeling with natural language information, particularly through large language models (LLMs), has recently emerged as a promising interdisciplinary research area. LLMs, having been trained on large corpora of…

Computation and Language · Computer Science 2024-11-04 Carl Edwards , Ziqing Lu , Ehsan Hajiramezanali , Tommaso Biancalani , Heng Ji , Gabriele Scalia

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

Large Language Models (LLMs) have demonstrated their transformative potential across numerous disciplinary studies, reshaping the existing research methodologies and fostering interdisciplinary collaboration. However, a systematic…

Computation and Language · Computer Science 2025-07-14 Lu Xiang , Yang Zhao , Yaping Zhang , Chengqing Zong

Large language models (LLMs) have gained significant attention in chemistry. However, most existing datasets center on molecular-level property prediction and overlook the role of fine-grained functional group (FG) information.…

Machine Learning · Computer Science 2026-02-17 Xuan Liu , Siru Ouyang , Xianrui Zhong , Jiawei Han , Huimin Zhao

Inspired by the exceptional general intelligence of Large Language Models (LLMs), researchers have begun to explore their application in pioneering the next generation of recommender systems - systems that are conversational, explainable,…

Information Retrieval · Computer Science 2024-08-06 Wensheng Lu , Jianxun Lian , Wei Zhang , Guanghua Li , Mingyang Zhou , Hao Liao , Xing Xie

Post-training alignment has increasingly become a crucial factor in enhancing the usability of language models (LMs). However, the strength of alignment varies depending on individual preferences. This paper proposes a method to incorporate…

Computation and Language · Computer Science 2026-01-13 Wenhong Zhu , Weinan Zhang , Rui Wang

Although Large Language Models (LLMs) achieve strong alignment through supervised fine-tuning and reinforcement learning from human feedback, the alignment is often fragile under subsequent fine-tuning. Existing explanations either…

Machine Learning · Computer Science 2026-05-19 Yuhan Huang , Huanran Chen , Yinpeng Dong

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Role-playing is important for Large Language Models (LLMs) to follow diverse instructions while maintaining role identity and the role's pre-defined ability limits. Existing role-playing datasets mostly contribute to controlling role style…

Computation and Language · Computer Science 2025-02-18 Junru Lu , Jiazheng Li , Guodong Shen , Lin Gui , Siyu An , Yulan He , Di Yin , Xing Sun

Large Language Models (LLMs) have demonstrated the ability to solve complex tasks through In-Context Learning (ICL), where models learn from a few input-output pairs without explicit fine-tuning. In this paper, we explore the capacity of…

Machine Learning · Computer Science 2024-11-26 Paimon Goulart , Evangelos E. Papalexakis

Recent years have witnessed increasing interests in prompt-based learning in which models can be trained on only a few annotated instances, making them suitable in low-resource settings. When using prompt-based learning for text…

Computation and Language · Computer Science 2023-05-11 Hongjing Li , Hanqi Yan , Yanran Li , Li Qian , Yulan He , Lin Gui

Pre-trained language models (PrLM) have to carefully manage input units when training on a very large text with a vocabulary consisting of millions of words. Previous works have shown that incorporating span-level information over…

Computation and Language · Computer Science 2021-09-16 Rongzhou Bao , Zhuosheng Zhang , Hai Zhao

Large Language Models (LLMs) have demonstrated exceptional proficiency in text understanding and embedding tasks. However, their potential in multimodal representation, particularly for item-to-item (I2I) recommendations, remains…

Information Retrieval · Computer Science 2025-01-22 Chao Zhang , Haoxin Zhang , Shiwei Wu , Di Wu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

Recommender systems are widely used in online services, with embedding-based models being particularly popular due to their expressiveness in representing complex signals. However, these models often function as a black box, making them…

Information Retrieval · Computer Science 2024-06-25 Yuxuan Lei , Jianxun Lian , Jing Yao , Xu Huang , Defu Lian , Xing Xie

Large language models (LLMs) exhibit remarkable capabilities across diverse tasks, yet aligning them efficiently and effectively with human expectations remains a critical challenge. This thesis advances LLM alignment by introducing novel…

Computation and Language · Computer Science 2025-06-12 Yuxin Jiang

The constitutional framework of alignment aims to align large language models (LLMs) with value-laden principles written in natural language (such as to avoid using biased language). Prior work has focused on parameter fine-tuning…

Computation and Language · Computer Science 2026-01-27 Henry Bell , Caroline Zhang , Mohammed Mobasserul Haque , Dhaval Potdar , Samia Zaman , Brandon Fain

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

Deep Metric Learning (DML) proposes to learn metric spaces which encode semantic similarities as embedding space distances. These spaces should be transferable to classes beyond those seen during training. Commonly, DML methods task…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Karsten Roth , Oriol Vinyals , Zeynep Akata

Based on the foundation of Large Language Models (LLMs), Multilingual LLMs (MLLMs) have been developed to address the challenges faced in multilingual natural language processing, hoping to achieve knowledge transfer from high-resource…

Computation and Language · Computer Science 2024-12-10 Yuemei Xu , Ling Hu , Jiayi Zhao , Zihan Qiu , Kexin XU , Yuqi Ye , Hanwen Gu