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Large language models (LLMs) encode a vast amount of semantic knowledge and possess remarkable understanding and reasoning capabilities. Previous work has explored how to ground LLMs in robotic tasks to generate feasible and executable…

Robotics · Computer Science 2024-09-17 Yanjiang Guo , Yen-Jen Wang , Lihan Zha , Jianyu Chen

Vision-language models (VLMs) offer a promising paradigm for image classification by comparing the similarity between images and class embeddings. A critical challenge lies in crafting precise textual representations for class names. While…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Songhao Han , Le Zhuo , Yue Liao , Si Liu

Multimodal Large Language Model (MLLMs) leverages Large Language Models as a cognitive framework for diverse visual-language tasks. Recent efforts have been made to equip MLLMs with visual perceiving and grounding capabilities. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Junwen He , Yifan Wang , Lijun Wang , Huchuan Lu , Jun-Yan He , Jin-Peng Lan , Bin Luo , Xuansong Xie

Large Language Models (LLMs) have made great strides in areas such as language processing and computer vision. Despite the emergence of diverse techniques to improve few-shot learning capacity, current LLMs fall short in handling the…

Biomolecules · Quantitative Biology 2024-05-14 Xianggen Liu , Yan Guo , Haoran Li , Jin Liu , Shudong Huang , Bowen Ke , Jiancheng Lv

Vision-language alignment in multi-modal large language models (MLLMs) relies on supervised fine-tuning (SFT) or reinforcement learning (RL). To align multi-modal large language models (MLLMs) in the post-training stage, supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Xin Jin , Siyuan Li , Siyong Jian , Kai Yu , Huan Wang

Reinforcement learning (RL) is a promising approach for aligning large language models (LLMs) knowledge with sequential decision-making tasks. However, few studies have thoroughly investigated the impact on LLM agents capabilities of…

We present $\textbf{MolT5}$ $-$ a self-supervised learning framework for pretraining models on a vast amount of unlabeled natural language text and molecule strings. $\textbf{MolT5}$ allows for new, useful, and challenging analogs of…

Computation and Language · Computer Science 2022-11-07 Carl Edwards , Tuan Lai , Kevin Ros , Garrett Honke , Kyunghyun Cho , Heng Ji

Recent advances in instruction-tuned Large Vision-Language Models (LVLMs) have imbued the models with the ability to generate high-level, image-grounded explanations with ease. While such capability is largely attributed to the rich world…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Jeonghwan Kim , Heng Ji

Fine-tuning significantly improves the performance of Large Language Models (LLMs), yet its underlying mechanisms remain poorly understood. This paper aims to provide an in-depth interpretation of the fine-tuning process through circuit…

Computation and Language · Computer Science 2025-06-16 Xu Wang , Yan Hu , Wenyu Du , Reynold Cheng , Benyou Wang , Difan Zou

Large Language Models (LLMs) have shown extraordinary success across various text generation tasks; however, their potential for simple yet essential text classification remains underexplored, as LLM pre-training tends to emphasize…

Computation and Language · Computer Science 2025-10-02 Zhexiong Liu , Diane Litman

Image-text retrieval requires the system to bridge the heterogenous gap between vision and language for accurate retrieval while keeping the network lightweight-enough for efficient retrieval. Existing trade-off solutions mainly study from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Jiamin Zhuang , Jing Yu , Yang Ding , Xiangyan Qu , Yue Hu

Large language models (LLMs) with billions of parameters and pretrained on massive amounts of data are now capable of near or better than state-of-the-art performance in a variety of downstream natural language processing tasks. Neural…

Computation and Language · Computer Science 2024-07-08 Victor Agostinelli , Max Wild , Matthew Raffel , Kazi Ahmed Asif Fuad , Lizhong Chen

Large language models (LLMs) often produce unsupported or unverifiable content, known as "hallucinations." To mitigate this, retrieval-augmented LLMs incorporate citations, grounding the content in verifiable sources. Despite such…

Information Retrieval · Computer Science 2024-08-26 Weijia Zhang , Mohammad Aliannejadi , Yifei Yuan , Jiahuan Pei , Jia-Hong Huang , Evangelos Kanoulas

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM…

Biomolecules · Quantitative Biology 2023-10-06 Zeyuan Wang , Qiang Zhang , Keyan Ding , Ming Qin , Xiang Zhuang , Xiaotong Li , Huajun Chen

Despite deep learning's success in chemistry, its impact is hindered by a lack of interpretability and an inability to resolve activity cliffs, where minor structural nuances trigger drastic property shifts. Current representation learning,…

Machine Learning · Computer Science 2026-03-26 Xiangsen Chen , Ruilong Wu , Yanyan Lan , Ting Ma , Yang Liu

Referring Expression Comprehension (REC) is a foundational cross-modal task that evaluates the interplay of language understanding, image comprehension, and language-to-image grounding. It serves as an essential testing ground for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Xuzheng Yang , Junzhuo Liu , Peng Wang , Guoqing Wang , Yang Yang , Heng Tao Shen

Aligned representations across languages is a desired property in multilingual large language models (mLLMs), as alignment can improve performance in cross-lingual tasks. Typically alignment requires fine-tuning a model, which is…

Computation and Language · Computer Science 2025-07-22 Anirudh Sundar , Sinead Williamson , Katherine Metcalf , Barry-John Theobald , Skyler Seto , Masha Fedzechkina

Existing large language models (LLMs) for machine translation are typically fine-tuned on sentence-level translation instructions and achieve satisfactory performance at the sentence level. However, when applied to document-level…

Computation and Language · Computer Science 2024-01-17 Yachao Li , Junhui Li , Jing Jiang , Min Zhang

Recent Multimodal Large Language Models (MLLMs) have demonstrated significant progress in perceiving and reasoning over multimodal inquiries, ushering in a new research era for foundation models. However, vision-language misalignment in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Wei-Yao Wang , Zhao Wang , Helen Suzuki , Yoshiyuki Kobayashi

Large language models (LLMs) have demonstrated their instruction-following capabilities and achieved powerful performance on various tasks. Inspired by their success, recent works in the molecular domain have led to the development of large…

Artificial Intelligence · Computer Science 2026-01-21 Jinyoung Park , Minseong Bae , Jeehye Na , Hyunwoo J. Kim
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