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Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Soham Rohit Chitnis , Sidong Liu , Tirtharaj Dash , Tanmay Tulsidas Verlekar , Antonio Di Ieva , Shlomo Berkovsky , Lovekesh Vig , Ashwin Srinivasan

State-of-the-art (SOTA) semi-supervised learning (SSL) methods have been highly successful in leveraging a mix of labeled and unlabeled data by combining techniques of consistency regularization and pseudo-labeling. During pseudo-labeling,…

Survival prediction using whole-slide images (WSIs) is crucial in cancer re-search. Despite notable success, existing approaches are limited by their reliance on sparse slide-level labels, which hinders the learning of discriminative…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Jiaqi Cui , Lu Wen , Yuchen Fei , Bo Liu , Luping Zhou , Dinggang Shen , Yan Wang

Self-supervised learning (SSL) methods have achieved remarkable success in learning image representations allowing invariances in them - but therefore discarding transformation information that some computer vision tasks actually require.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Qin Wang , Alessio Quercia , Benjamin Bruns , Abigail Morrison , Hanno Scharr , Kai Krajsek

Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

Pre-training has been an important ingredient in developing strong monocular depth estimation models in recent years. For instance, self-supervised learning (SSL) is particularly effective by alleviating the need for large datasets with…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Muhammad Osama Khan , Junbang Liang , Chun-Kai Wang , Shan Yang , Yu Lou

In medical image analysis, the cost of acquiring high-quality data and their annotation by experts is a barrier in many medical applications. Most of the techniques used are based on supervised learning framework and need a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Siladittya Manna , Saumik Bhattacharya , Umapada Pal

Whole Slide Image (WSI) representation is critical for cancer subtyping, cancer recognition and mutation prediction.Training an end-to-end WSI representation model poses significant challenges, as a standard gigapixel slide can contain tens…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Jing Jin , Xu Liu , Te Gao , Zhihong Shi , Yixiong Liang , Ruiqing Zheng , Hulin Kuang , Min Zeng , Shichao Kan

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

The representation learning problem in the oil & gas industry aims to construct a model that provides a representation based on logging data for a well interval. Previous attempts are mainly supervised and focus on similarity task, which…

Artificial Intelligence · Computer Science 2023-11-14 Alexander Marusov , Alexey Zaytsev

Though self-supervised learning (SSL) has demonstrated incredible ability to learn robust representations from unlabeled data, the choice of optimal SSL strategy can lead to vastly different performance outcomes in specialized domains.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Vedrana Ivezić , Mara Pleasure , Ashwath Radhachandran , Saarang Panchavati , Shreeram Athreya , Vivek Sant , Benjamin Emert , Gregory Fishbein , Corey Arnold , William Speier

Weakly supervised whole slide image (WSI) classification is challenging due to the lack of patch-level labels and high computational costs. State-of-the-art methods use self-supervised patch-wise feature representations for multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Wentao Huang , Xiaoling Hu , Shahira Abousamra , Prateek Prasanna , Chao Chen

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

This paper demonstrates that spatial information can be used to learn interpretable representations in medical images using Self-Supervised Learning (SSL). Our proposed method, ISImed, is based on the observation that medical images exhibit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Nabil Jabareen , Dongsheng Yuan , Sören Lukassen

A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e., one embedding, to each WSI. With the existence of many pre-trained deep neural networks…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Sobhan Hemati , Ghazal Alabtah , Saghir Alfasly , H. R. Tizhoosh

Whole slide image (WSI) processing is becoming part of the key components of standard clinical diagnosis for various diseases. However, the direct application of conventional image processing algorithms to WSI faces certain obstacles…

Computer Vision and Pattern Recognition · Computer Science 2023-09-18 Yuanfeng Wu , Shaojie Li , Zhiqiang Du , Wentao Zhu

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

The success of self-supervised learning (SSL) has mostly been attributed to the availability of unlabeled yet large-scale datasets. However, in a specialized domain such as medical imaging which is a lot different from natural images, the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Soumitri Chattopadhyay , Soham Ganguly , Sreejit Chaudhury , Sayan Nag , Samiran Chattopadhyay