Related papers: Efficient Brain Imaging Analysis for Alzheimer's a…
In recent days, Convolutional Neural Networks (CNN) have demonstrated impressive performance in medical image analysis. However, there is a lack of clear understanding of why and how the Convolutional Neural Network performs so well for…
Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…
Accurately discriminating progressive stages of Alzheimer's Disease (AD) is crucial for early diagnosis and prevention. It often involves multiple imaging modalities to understand the complex pathology of AD, however, acquiring a complete…
Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…
Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…
Emerging evidence shows that cognitive deficits in Alzheimer disease (AD) are associated with disruptions in brain functional connectivity. Thus, the identification of alterations in AD functional networks has become a topic of increasing…
With the increasing incidence of neurodegenerative diseases such as Alzheimer's Disease (AD), there is a need for further research that enhances detection and monitoring of the diseases. We present MORPHADE (Morphological Autoencoders for…
Alzheimer's disease (AD) is the leading cause of dementia, and its early detection is crucial for effective intervention, yet current diagnostic methods often fall short in sensitivity and specificity. This study aims to detect significant…
This report provides an overview of the current state of the art deep learning architectures and optimisation techniques, and uses the ADNI hippocampus MRI dataset as an example to compare the effectiveness and efficiency of different…
Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…
Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…
Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…
Previous works in the literature apply 3D spatial-only models on 4D functional MRI data leading to possible sub-par feature extraction to be used for downstream tasks like classification. In this work, we aim to develop a novel 4D…
We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…
Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…
Accurate and efficient classification of Alzheimer's disease (AD) severity from brain magnetic resonance imaging (MRI) remains a critical challenge, particularly when limited data and model interpretability are of concern. In this work, we…
The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…
Alzheimer's disease (AD) is a serious neurodegenerative disease consisting of four stages where the illness gets progressively worse. It is of great significance to detect the gene regulatory mechanism as AD progresses and, thus, to help us…
The diagnosis of Alzheimer's disease (AD) in routine clinical practice is most commonly based on subjective clinical interpretations. Quantitative electroencephalography (QEEG) measures have been shown to reflect neurodegenerative processes…