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Depression and Attention Deficit Hyperactivity Disorder (ADHD) stand out as the common mental health challenges today. In affective computing, speech signals serve as effective biomarkers for mental disorder assessment. Current research,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-05 Shuanglin Li , Siyang Song , Rajesh Nair , Syed Mohsen Naqvi

Normative modeling has emerged as a pivotal approach for characterizing heterogeneity and individual variance in neurodegenerative diseases, notably Alzheimer's disease(AD). One of the challenges of cortical normative modeling is the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-13 Jianwei Zhang , Yonggang Shi

Alzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Nasser A Alsadhan

Alzheimer's Disease (AD) is a neurodegenerative disease affecting millions of individuals across the globe. As the prevalence of this disease continues to rise, early diagnosis is crucial to improve clinical outcomes. Neural networks,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-06 Akshay Sunkara , Rajiv Morthala , Anav Jain , Srinjoy Ghose , Santosh Morthala

Alzheimer's disease is a progressive form of dementia that results in problems with memory, thinking, and behavior. It often starts with abnormal aggregation and deposition of beta amyloid and tau, followed by neuronal damage such as…

Applications · Statistics 2022-06-03 Dengdeng Yu , Linbo Wang , Dehan Kong , Hongtu Zhu

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Fayao Liu , Chunhua Shen

Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Hossein Yousefi-Banaem , Saber Malekzadeh

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

Machine Learning · Computer Science 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang

Brain extraction (skull stripping) is a challenging problem in neuroimaging. It is due to the variability in conditions from data acquisition or abnormalities in images, making brain morphology and intensity characteristics changeable and…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Duy H. M. Nguyen , Duy M. Nguyen , Mai T. N. Truong , Thu Nguyen , Khanh T. Tran , Nguyen A. Triet , Pham T. Bao , Binh T. Nguyen

Alzheimer's disease (AD) is a major neurodegenerative condition that affects millions around the world. As one of the main biomarkers in the AD diagnosis procedure, brain amyloid positivity is typically identified by positron emission…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Yanxi Chen , Mohammad Farazi , Zhangsihao Yang , Yonghui Fan , Nicholas Ashton , Eric M Reiman , Yi Su , Yalin Wang

Alzheimer's disease (AD) is characterized by the progressive spread of pathology across brain networks, yet forecasting this cascade at the individual level remains challenging. We present a personalized graph-based dynamical model that…

Neurons and Cognition · Quantitative Biology 2025-11-13 Chunyan Li , Yutong Mao , Xiao Liu , Wenrui Hao

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…

Machine Learning · Computer Science 2023-11-08 Xulong Wang , Yu Zhang , Menghui Zhou , Tong Liu , Jun Qi , Po Yang

Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Early diagnosis and precise treatment are essential for ASD patients. Although researchers have built many analytical models, there has been limited progress in…

Neurons and Cognition · Quantitative Biology 2018-10-30 Juntang Zhuang , Nicha C. Dvornek , Xiaoxiao Li , Pamela Ventola , James S. Duncan

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Siva Manohar Reddy Kesu , Neelam Sinha , Hariharan Ramasangu , Thomas Gregor Issac

Alzheimer's disease is a debilitating disorder marked by a decline in cognitive function. Timely identification of the disease is essential for the development of personalized treatment strategies that aim to mitigate its progression. The…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Hong , Kaifeng Huang

Tensor-based morphometry (TBM) aims at showing local differences in brain volumes with respect to a common template. TBM images are smooth but they exhibit (especially in diseased groups) higher values in some brain regions called lateral…

Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Benjamin Lambert , Maxime Louis , Senan Doyle , Florence Forbes , Michel Dojat , Alan Tucholka

Alzheimer's Disease (AD) is a progressive neurodegenerative disease and the leading cause of dementia. Early diagnosis is critical for patients to benefit from potential intervention and treatment. The retina has been hypothesized as a…

Machine Learning · Computer Science 2023-03-20 Nooshin Yousefzadeh , Charlie Tran , Adolfo Ramirez-Zamora , Jinghua Chen , Ruogu Fang , My T. Thai
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