Related papers: Efficient Brain Imaging Analysis for Alzheimer's a…
The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…
Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…
Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…
Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in…
The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the leading cause of dementia, significantly impacting cost, mortality, and burden worldwide. The advent of high-throughput omics technologies, such as genomics,…
Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…
Alzheimer's disease (AD) develops over a prolonged preclinical phase, during which neuropathological changes accumulate long before cognitive symptoms appear. Identifying cognitive functions affected at early stages is critical for the…
We propose a novel framework for Alzheimer's disease (AD) detection using brain MRIs. The framework starts with a data augmentation method called Brain-Aware Replacements (BAR), which leverages a standard brain parcellation to replace…
Graph theoretical methods have proven valuable for investigating alterations in both anatomical and functional brain connectivity networks during Alzheimer's disease (AD). Recent studies suggest that representing brain networks in a…
Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…
The detection of Alzheimer's disease (AD) from spontaneous speech has attracted increasing attention while the sparsity of training data remains an important issue. This paper handles the issue by knowledge transfer, specifically from both…
Currently, the diagnosis of Alzheimer's disease is a complex and error-prone process. Improving this diagnosis could allow earlier detection of the disease and improve the quality of life of patients and their families. For this work, we…
Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…
Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions worldwide. In the absence of effective treatment options, early diagnosis is crucial for initiating management strategies to delay disease onset and slow down…
We propose an interpretable 3D Grid-Attention deep neural network that can accurately predict a person's age and whether they have Alzheimer's disease (AD) from a structural brain MRI scan. Building on a 3D convolutional neural network, we…
Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs cognitive function and quality of life. Timely intervention in AD relies heavily on early and precise diagnosis, which remains challenging due to the…
Accurate diagnosis of Alzheimer's Disease (AD) entails clinical evaluation of multiple cognition metrics and biomarkers. Metrics such as the Alzheimer's Disease Assessment Scale - Cognitive test (ADAS-cog) comprise multiple subscores that…
Interpretability is a critical factor in applying complex deep learning models to advance the understanding of brain disorders in neuroimaging studies. To interpret the decision process of a trained classifier, existing techniques typically…