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Complex systems are often characterized by the interplay of multiple interconnected dynamical processes operating across a range of temporal scales. This phenomenon is widespread in both biological and artificial scenarios, making it…

Statistical Mechanics · Physics 2025-09-08 Giorgio Nicoletti , Daniel M. Busiello

Biological cells encode information about their environment through biochemical signaling networks that control their internal state and response. This information is often encoded in the dynamical patterns of the signaling molecules,…

Molecular Networks · Quantitative Biology 2023-04-24 Lauritz Hahn , Aleksandra M. Walczak , Thierry Mora

Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…

Biological Physics · Physics 2018-02-14 Yoshihiko Hasegawa

Complex systems are characterized by multiple spatial and temporal scales. A natural framework to capture their multiscale nature is that of multilayer networks, where different layers represent distinct physical processes that often…

Statistical Mechanics · Physics 2024-04-29 Giorgio Nicoletti , Daniel Maria Busiello

Nonlinear dynamic models are widely used for characterizing functional forms of processes that govern complex biological pathway systems. Over the past decade, validation and further development of these models became possible due to data…

Methodology · Statistics 2019-08-13 Itai Dattner , Shota Gugushvili , Harold Ship , Eberhard O. Voit

The proliferation of deep learning applications has intensified the demand for electronic hardware with low energy consumption and fast computing speed. Neuromorphic photonics have emerged as a viable alternative to directly process…

Applied Physics · Physics 2025-06-24 Guangfeng You , Chao Qian , Hongsheng Chen

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Neural systems process information across a broad range of intrinsic timescales, both within and across cortical areas. While such diversity is a hallmark of biological networks, its computational role in nonlinear information processing…

Neurons and Cognition · Quantitative Biology 2025-06-10 Tomoki Kurikawa

Research toward powerful information processing systems that circumvent the interconnect bottleneck by exploiting the nonlinear evolution of multiple phase dynamics in locally connected arrays is discussed. We focus on a scheme in which…

Neural and Evolutionary Computing · Computer Science 2016-03-23 Richard A. Kiehl

Signal processing traditionally relies on classical statistical modeling techniques. Such model-based methods utilize mathematical formulations that represent the underlying physics, prior information and additional domain knowledge. Simple…

Signal Processing · Electrical Eng. & Systems 2023-06-08 Nir Shlezinger , Yonina C. Eldar

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

Analysis of PDEs · Mathematics 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

Biological neural systems encode and transmit information as patterns of activity tracing complex trajectories in high-dimensional state-spaces, inspiring alternative paradigms of information processing. Heteroclinic networks, naturally…

Neurons and Cognition · Quantitative Biology 2021-10-26 Giovanni Sirio Carmantini , Fabio Schittler Neves , Marc Timme , Serafim Rodrigues

Information processing in the brain requires integration of information over time. Such an integration can be achieved if signals are maintained in the network activity for the required period, as quantified by the intrinsic timescale.…

In science and engineering, intelligent processing of complex signals such as images, sound or language is often performed by a parameterized hierarchy of nonlinear processing layers, sometimes biologically inspired. Hierarchical systems…

Machine Learning · Computer Science 2012-12-27 Miguel Á. Carreira-Perpiñán , Weiran Wang

There is an urgent reflection on traditional nonlinear signal processing methods in communications before Artificial Intelligence (AI) dominates the field. It implies a need to reassess or reinterpret established theories and tools,…

Signal Processing · Electrical Eng. & Systems 2025-11-05 Ana Pérez-Neira , Marc Martinez-Gost , Miguel Ángel Lagunas

Machine learning is increasingly recognized as a promising technology in the biological, biomedical, and behavioral sciences. There can be no argument that this technique is incredibly successful in image recognition with immediate…

Imaging systems have traditionally been designed to mimic the human eye and produce visually interpretable measurements. Modern imaging systems, however, process raw measurements computationally before or instead of human viewing. As a…

Deep learning methods have revolutionized speech recognition, image recognition, and natural language processing since 2010. Each of these tasks involves a single modality in their input signals. However, many applications in the artificial…

Artificial Intelligence · Computer Science 2020-07-15 Chao Zhang , Zichao Yang , Xiaodong He , Li Deng

Optical information processing and computing can potentially offer enhanced performance, scalability and energy efficiency. However, achieving nonlinearity-a critical component of computation-remains challenging in the optical domain. Here…

Deep neural networks have achieved remarkable breakthroughs by leveraging multiple layers of data processing to extract hidden representations, albeit at the cost of large electronic computing power. To enhance energy efficiency and speed,…

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