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Biological information processing manifests a huge variety in its complexity and capability among different organisms, which presumably stems from the evolutionary optimization under limited computational resources. Starting from the…

Biological Physics · Physics 2025-10-21 Takehiro Tottori , Tetsuya J. Kobayashi

Biological and artificial information processing systems form representations of the world that they can use to categorize, reason, plan, navigate, and make decisions. How can we measure the similarity between the representations formed by…

Nonlinear computation is essential for a wide range of information processing tasks, yet implementing nonlinear functions using optical systems remains a challenge due to the weak and power-intensive nature of optical nonlinearities.…

Optics · Physics 2025-11-10 Md Sadman Sakib Rahman , Yuhang Li , Xilin Yang , Shiqi Chen , Aydogan Ozcan

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…

Biological Physics · Physics 2016-12-07 Bernhard Fichtl , Matthias F. Schneider

Intelligently reasoning about the world often requires integrating data from multiple modalities, as any individual modality may contain unreliable or incomplete information. Prior work in multimodal learning fuses input modalities only…

Machine Learning · Computer Science 2020-11-17 George Barnum , Sabera Talukder , Yisong Yue

An outstanding problem in neuroscience is to understand how information is integrated across the many modules of the brain. While classic information-theoretic measures have transformed our understanding of feedforward information…

Neurons and Cognition · Quantitative Biology 2019-02-12 Daniel Toker , Friedrich T. Sommer

The simulation of large nonlinear dynamical systems, including systems generated by discretization of hyperbolic partial differential equations, can be computationally demanding. Such systems are important in both fluid and kinetic…

Plasma Physics · Physics 2021-06-14 Alexander Engel , Graeme Smith , Scott E. Parker

Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here we study the classic model of weakly activated cascades and obtain…

Molecular Networks · Quantitative Biology 2016-09-15 Mariano Beguerisse-Diaz , Radhika Desikan , Mauricio Barahona

Non-isolated systems have diverse coupling relations with the external environment. These relations generate complex thermodynamics and information transmission between the system and its environment. The framework depicted in the current…

Statistical Mechanics · Physics 2022-06-15 Yang Tian , Pei Sun

The informational synthesis of neural structures, processes, parameters and characteristics that allow a unified description and modeling as neural machines of natural and artificial neural systems is presented. The general informational…

Neural and Evolutionary Computing · Computer Science 2024-04-08 Iosif Iulian Petrila

Designing metamaterials that carry out advanced computations poses a significant challenge. A powerful design strategy splits the problem into two steps: First, encoding the desired functionality in a discrete or tight-binding model, and…

Mesoscale and Nanoscale Physics · Physics 2025-09-03 Sima Zahedi Fard , Paolo Tiso , Parisa Omidvar , Marc Serra-Garcia

Information transmission in biological signaling circuits has often been described using the metaphor of a noise filter. Cellular systems need accurate, real-time data about their environmental conditions, but the biochemical reaction…

Molecular Networks · Quantitative Biology 2019-02-27 David Hathcock , James Sheehy , Casey Weisenberger , Efe Ilker , Michael Hinczewski

Neuromorphic applications emulate the processing performed by the brain by using spikes as inputs instead of time-varying analog stimuli. Therefore, these time-varying stimuli have to be encoded into spikes, which can induce important…

Neural and Evolutionary Computing · Computer Science 2024-12-30 Ahmad El Ferdaoussi , Eric Plourde , Jean Rouat

In the human brain, sequences of language input are processed within a distributed and hierarchical architecture, in which higher stages of processing encode contextual information over longer timescales. In contrast, in recurrent neural…

Computation and Language · Computer Science 2021-03-19 Hsiang-Yun Sherry Chien , Jinhan Zhang , Christopher. J. Honey

Image processing is one of the most promising applications for quantum machine learning (QML). Quanvolutional Neural Networks with non-trainable parameters are the preferred solution to run on current and near future quantum devices. The…

Quantum Physics · Physics 2024-10-10 Daniele Lizzio Bosco , Beatrice Portelli , Giuseppe Serra

An algorithm for a family of self-starting high-order implicit time integration schemes with controllable numerical dissipation is proposed for both linear and nonlinear transient problems. This work builds on the previous works of the…

Numerical Analysis · Mathematics 2024-09-23 Daniel O'Shea , Xiaoran Zhang , Shayan Mohammadian , Chongmin Song

Nonlinear subspace clustering based on a feed-forward neural network has been demonstrated to provide better clustering accuracy than some advanced subspace clustering algorithms. While this approach demonstrates impressive outcomes, it…

Machine Learning · Computer Science 2024-08-28 Long Shi , Lei Cao , Zhongpu Chen , Badong Chen , Yu Zhao

The recent rapid increase in demand for data processing has resulted in the need for novel machine learning concepts and hardware. Physical reservoir computing and an extreme learning machine are novel computing paradigms based on physical…

Optics · Physics 2021-04-02 Satoshi Sunada , Kazutaka Kanno , Atsushi Uchida

Across scientific domains, a fundamental challenge is to characterize and compute the mappings from underlying physical processes to observed signals and measurements. While nonlinear neural networks have achieved considerable success, they…

Machine Learning · Computer Science 2025-08-11 Alexander DeLise , Kyle Loh , Krish Patel , Meredith Teague , Andrea Arnold , Matthias Chung