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Automated cell segmentation in microscopy images is essential for biomedical research, yet conventional methods are labor-intensive and prone to error. While deep learning-based approaches have proven effective, they often require large…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Rüveyda Yilmaz , Kaan Keven , Yuli Wu , Johannes Stegmaier

Urinalysis is a standard diagnostic test to detect urinary system related problems. The automation of urinalysis will reduce the overall diagnostic time. Recent studies used urine microscopic datasets for designing deep learning based…

Quantitative Methods · Quantitative Biology 2021-11-23 Dipam Goswami , Hari Om Aggrawal , Rajiv Gupta , Vinti Agarwal

Analysis of microscopy images is one important tool in many fields of biomedical research, as it allows the quantification of a multitude of parameters at the cellular level. However, manual counting of these images is both tiring and…

Computer Vision and Pattern Recognition · Computer Science 2013-11-13 P. A Nogueira

We present Glioma C6, a new open dataset for instance segmentation of glioma C6 cells, designed as both a benchmark and a training resource for deep learning models. The dataset comprises 75 high-resolution phase-contrast microscopy images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Roman Malashin , Svetlana Pashkevich , Daniil Ilyukhin , Arseniy Volkov , Valeria Yachnaya , Andrey Denisov , Maria Mikhalkova

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

In microscopy image cell segmentation, it is common to train a deep neural network on source data, containing different types of microscopy images, and then fine-tune it using a support set comprising a few randomly selected and annotated…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Youssef Dawoud , Arij Bouazizi , Katharina Ernst , Gustavo Carneiro , Vasileios Belagiannis

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

Single-cell analysis is currently one of the most high-resolution techniques to study biology. The large complex datasets that have been generated have spurred numerous developments in computational biology, in particular the use of…

Genomics · Quantitative Biology 2023-04-27 Ionut Sebastian Mihai , Sarang Chafle , Johan Henriksson

Image-based or morphological profiling is a rapidly expanding field wherein cells are "profiled" by extracting hundreds to thousands of unbiased, quantitative features from images of cells that have been perturbed by genetic or chemical…

Quantitative Methods · Quantitative Biology 2024-11-07 Erin Weisbart , Ankur Kumar , John Arevalo , Anne E. Carpenter , Beth A. Cimini , Shantanu Singh

Methods: We have developed a software suite (DataSet Tracker) for real-time analysis designed to run on computers, smartphones, and smart glasses hardware and suitable for resource-constrained, on-the-fly computing in microscopes without…

Quantitative Methods · Quantitative Biology 2025-08-13 Alexandre Matov

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

The amount of image datasets collected for environmental monitoring purposes has increased in the past years as computer vision assisted methods have gained interest. Computer vision applications rely on high-quality datasets, making data…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Mikko Impiö , Philipp M. Rehsen , Jenni Raitoharju

Many fields, such as neuroscience, are experiencing the vast proliferation of cellular data, underscoring the need for organizing and interpreting large datasets. A popular approach partitions data into manageable subsets via hierarchical…

Quantitative Methods · Quantitative Biology 2024-03-07 Diek W. Wheeler , Giorgio A. Ascoli

This article describes the design, implementation, and results of the latest installment of the dermoscopic image analysis benchmark challenge. The goal is to support research and development of algorithms for automated diagnosis of…

Biological cells, by definition, are the basic units which contain the fundamental molecules of life of which all living things are composed. Understanding how they function and differentiating cells from one another therefore is of…

Signal Processing · Electrical Eng. & Systems 2021-01-07 Hassan Raji , Muhammad Tayyab , Jianye Sui , Seyed Reza Mahmoodi , Mehdi Javanmard

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Jianxu Chen , Chukka Srinivas

Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu

Motivation: Innovative microfluidic systems carry the promise to greatly facilitate spatio-temporal analysis of single cells under well-defined environmental conditions, allowing novel insights into population heterogeneity and opening new…

Machine Learning · Computer Science 2021-05-18 Dominik Stallmann , Jan P. Göpfert , Julian Schmitz , Alexander Grünberger , Barbara Hammer

Traditional deep learning-based methods for classifying cellular features in microscopy images require time- and labor-intensive processes for training models. Among the current limitations are major time commitments from domain experts for…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Abhiram Kandiyana , Peter R. Mouton , Yaroslav Kolinko , Lawrence O. Hall , Dmitry Goldgof