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The hippocampus is an important brain structure involved in various psychiatric disorders, and its automatic and accurate segmentation is vital for studying these diseases. Recently, deep learning-based methods have made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Guanghua He , Wangang Cheng , Hancan Zhu , Gaohang Yu

Inspired by the success of large language models (LLM) for DNA and proteins, several LLM for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to learn, in a self-supervised way, how to represent each RNA base…

Artificial Intelligence · Computer Science 2025-02-04 L. I. Zablocki , L. A. Bugnon , M. Gerard , L. Di Persia , G. Stegmayer , D. H. Milone

The task of Named Entity Recognition (NER) is an important component of many natural language processing systems, such as relation extraction and knowledge graph construction. In this work, we present a simple and effective approach for…

Computation and Language · Computer Science 2022-03-29 Urchade Zaratiana , Pierre Holat , Nadi Tomeh , Thierry Charnois

Machine learning methods have recently achieved high-performance in biomedical text analysis. However, a major bottleneck in the widespread application of these methods is obtaining the required large amounts of annotated training data,…

Machine Learning · Computer Science 2019-12-06 Xing Meng , Craig H. Ganoe , Ryan T. Sieberg , Yvonne Y. Cheung , Saeed Hassanpour

This study is dedicated to exploring the application of prompt learning methods to advance Named Entity Recognition (NER) within the medical domain. In recent years, the emergence of large-scale models has driven significant progress in NER…

Computation and Language · Computer Science 2025-06-04 Jinzhu Yang

Although rare diseases are characterized by low prevalence, approximately 300 million people are affected by a rare disease. The early and accurate diagnosis of these conditions is a major challenge for general practitioners, who do not…

Computation and Language · Computer Science 2021-11-12 Isabel Segura-Bedmar , David Camino-Perdonas , Sara Guerrero-Aspizua

Predicting cellular responses to genetic perturbations represents a fundamental challenge in systems biology, critical for advancing therapeutic discovery and virtual cell modeling. While large language models (LLMs) show promise for…

In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER…

Computation and Language · Computer Science 2020-09-22 Usman Naseem , Matloob Khushi , Vinay Reddy , Sakthivel Rajendran , Imran Razzak , Jinman Kim

Non-coding RNA are functional molecules that are not translated into proteins. Their function comes as important regulators of biological function. Because they are not translated, they need not be as stable as other types of RNA. The TKF91…

Other Quantitative Biology · Quantitative Biology 2024-05-27 Brandon Legried

In this work, we represent Lex-BERT, which incorporates the lexicon information into Chinese BERT for named entity recognition (NER) tasks in a natural manner. Instead of using word embeddings and a newly designed transformer layer as in…

Computation and Language · Computer Science 2021-04-19 Wei Zhu , Daniel Cheung

Malicious URL detection and webpage classification are critical tasks in cybersecurity and information management. In recent years, extensive research has explored using BERT or similar language models to replace traditional machine…

Cryptography and Security · Computer Science 2025-05-27 Yujie Li , Yiwei Liu , Peiyue Li , Yifan Jia , Yanbin Wang

Classifiers are an important and defining feature of the Chinese language, and their correct prediction is key to numerous educational applications. Yet, whether the most popular Large Language Models (LLMs) possess proper knowledge the…

Computation and Language · Computer Science 2025-11-04 Ziqi Zhang , Jianfei Ma , Emmanuele Chersoni , Jieshun You , Zhaoxin Feng

Noncoding RNAs are integral to a wide range of biological processes, including translation, gene regulation, host-pathogen interactions and environmental sensing. While genomics is now a mature field, our capacity to identify noncoding RNA…

This study proposes a large language model optimization method based on the improved LoRA fine-tuning algorithm, aiming to improve the accuracy and computational efficiency of the model in natural language processing tasks. We fine-tune the…

Computation and Language · Computer Science 2024-12-30 Jiacheng Hu , Xiaoxuan Liao , Jia Gao , Zhen Qi , Hongye Zheng , Chihang Wang

Sequential recommendation systems predict the next interaction item based on users' past interactions, aligning recommendations with individual preferences. Leveraging the strengths of Large Language Models (LLMs) in knowledge comprehension…

Information Retrieval · Computer Science 2025-01-22 Xiaoyu Kong , Jiancan Wu , An Zhang , Leheng Sheng , Hui Lin , Xiang Wang , Xiangnan He

RNA-sequencing (RNA-seq) has become an exemplar technology in modern biology and clinical applications over the past decade. It has gained immense popularity in the recent years driven by continuous efforts of the bioinformatics community…

Large language models (LLMs) have recently demonstrated state-of-the-art performance across various natural language processing (NLP) tasks, achieving near-human levels in multiple language understanding challenges and aligning closely with…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Zhenyi Wang , Li Zou , Shengyun Wei , Kai Li , Feifan Liao , Haibo Mi , Rongxuan Lai

Background: The expanding research in the field of long non-coding RNAs(lncRNAs) showed abnormal expression of lncRNAs in many complex diseases. Accurately identifying lncRNA-disease association is essential in understanding lncRNA…

Quantitative Methods · Quantitative Biology 2020-06-24 Manu Madhavan , Gopakumar G

Bidirectional Encoder Representations from Transformers or BERT~\cite{devlin-etal-2019-bert} has been one of the base models for various NLP tasks due to its remarkable performance. Variants customized for different languages and tasks are…

Computation and Language · Computer Science 2022-11-22 Ting Han , Kunhao Pan , Xinyu Chen , Dingjie Song , Yuchen Fan , Xinyu Gao , Ruyi Gan , Jiaxing Zhang

Transformer-based models have achieved remarkable success in natural language and vision tasks, but their application to gene expression analysis remains limited due to data sparsity, high dimensionality, and missing values. We present…

Machine Learning · Computer Science 2025-04-15 Shuai Jiang , Saeed Hassanpour
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