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Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Multimodal Large Language Models (MLLMs) have achieved remarkable progress in domains such as visual understanding and mathematical reasoning. However, their application in the medical domain is constrained by two key challenges: (1)…

Computation and Language · Computer Science 2025-10-09 Zeyu Liu , Zhitian Hou , Guanghao Zhu , Zhijie Sang , Congkai Xie , Hongxia Yang

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

Reasoning is increasingly crucial for various tasks. While chain-of-thought prompting enables large language models to leverage reasoning effectively, harnessing the reasoning capabilities of Vision-Language Models (VLMs) remains…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Guande Wu , Huan Song , Yawei Wang , Qiaojing Yan , Yijun Tian , Lin Lee Cheong , Panpan Xu

Transferring the reasoning capability from stronger large language models (LLMs) to smaller ones has been quite appealing, as smaller LLMs are more flexible to deploy with less expense. Among the existing solutions, knowledge distillation…

Computation and Language · Computer Science 2024-11-26 Yijun Tian , Yikun Han , Xiusi Chen , Wei Wang , Nitesh V. Chawla

Background: Retrieval augmented generation (RAG) technology can empower large language models (LLMs) to generate more accurate, professional, and timely responses without fine tuning. However, due to the complex reasoning processes and…

Computation and Language · Computer Science 2026-02-27 Jianmin Li , Ying Chang , Su-Kit Tang , Yujia Liu , Yanwen Wang , Shuyuan Lin , Binkai Ou

Deep learning has advanced NLP, but interpretability remains limited, especially in healthcare and finance. Concept bottleneck models tie predictions to human concepts in vision, but NLP versions either use binary activations that harm text…

Computation and Language · Computer Science 2026-03-31 Yibo Yang

Effective code generation with language models hinges on two critical factors: accurately understanding the intent of the prompt and generating code that applies algorithmic reasoning to produce correct solutions capable of passing diverse…

Artificial Intelligence · Computer Science 2025-10-21 Amir Jalilifard , Anderson de Rezende Rocha , Marcos Medeiros Raimundo

Multimodal Large Language Models (MLLMs) have shown impressive capabilities in jointly understanding text, images, and videos, often evaluated via Visual Question Answering (VQA). However, even state-of-the-art MLLMs struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Alberto Compagnoni , Marco Morini , Sara Sarto , Federico Cocchi , Davide Caffagni , Marcella Cornia , Lorenzo Baraldi , Rita Cucchiara

The application of reinforcement learning (RL) to enhance the reasoning capabilities of Multimodal Large Language Models (MLLMs) constitutes a rapidly advancing research area. While MLLMs extend Large Language Models (LLMs) to handle…

Artificial Intelligence · Computer Science 2025-05-22 Guanghao Zhou , Panjia Qiu , Cen Chen , Jie Wang , Zheming Yang , Jian Xu , Minghui Qiu

Logical reasoning is fundamental for humans yet presents a substantial challenge in the domain of Artificial Intelligence. Initially, researchers used Knowledge Representation and Reasoning (KR) systems that did not scale and required…

Computation and Language · Computer Science 2024-04-02 Man Luo , Shrinidhi Kumbhar , Ming shen , Mihir Parmar , Neeraj Varshney , Pratyay Banerjee , Somak Aditya , Chitta Baral

Unlocking deep and interpretable biological reasoning from complex genomic data remains a major AI challenge limiting scientific progress. While current DNA foundation models excel at representing sequences, they struggle with multi-step…

In recent years, multimodal large language models (MLLMs) have achieved significant breakthroughs, enhancing understanding across text and vision. However, current MLLMs still face challenges in effectively integrating knowledge across…

Computation and Language · Computer Science 2025-03-10 Boyu Jia , Junzhe Zhang , Huixuan Zhang , Xiaojun Wan

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Clinical antimicrobial therapy requires the dynamic integration of pathogen profiles,host factors, pharmacological properties of antimicrobials,and the severity of infection. This complexity imposes fundamental limitations on the…

Artificial Intelligence · Computer Science 2025-11-27 Zhe Li , Yehan Qiu , Yujie Chen , Xiang Zhou

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

Computation and Language · Computer Science 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan
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