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Synthetic data generation has the potential to impact applications and domains with scarce data. However, before such data is used for sensitive tasks such as mental health, we need an understanding of how different demographics are…

Artificial Intelligence · Computer Science 2024-03-26 Shinka Mori , Oana Ignat , Andrew Lee , Rada Mihalcea

Smartwatch health sensor data are increasingly utilized in smart health applications and patient monitoring, including stress detection. However, such medical data often comprise sensitive personal information and are resource-intensive to…

Machine Learning · Computer Science 2026-02-03 Lucas Lange , Nils Wenzlitschke , Erhard Rahm

Data plays a fundamental role in consolidating markets, services, and products in the digital financial ecosystem. However, the use of real data, especially in the financial context, can lead to privacy risks and access restrictions,…

Many ground-breaking advancements in machine learning can be attributed to the availability of a large volume of rich data. Unfortunately, many large-scale datasets are highly sensitive, such as healthcare data, and are not widely available…

Machine Learning · Computer Science 2020-12-09 James Jordon , Alan Wilson , Mihaela van der Schaar

The increasing reliance on machine learning (ML) models for decision-making requires high-quality training data. However, access to real-world datasets is often restricted due to privacy concerns, proprietary restrictions, and incomplete…

Machine Learning · Computer Science 2026-04-30 Alessandra Agostini , Andrea Maurino , Blerina Spahiu

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

The performance of modern machine learning systems depends on access to large, high-quality datasets, often sourced from user-generated content or proprietary, domain-specific corpora. However, these rich datasets inherently contain…

Cryptography and Security · Computer Science 2025-08-28 Zhan Shi , Yefeng Yuan , Yuhong Liu , Liang Cheng , Yi Fang

Privacy-preserving synthetic data offers a promising solution to harness segregated data in high-stakes domains where information is compartmentalized for regulatory, privacy, or institutional reasons. This survey provides a comprehensive…

Cryptography and Security · Computer Science 2025-03-28 Viktor Schlegel , Anil A Bharath , Zilong Zhao , Kevin Yee

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Access to electronic health record (EHR) data has motivated computational advances in medical research. However, various concerns, particularly over privacy, can limit access to and collaborative use of EHR data. Sharing synthetic EHR data…

Machine Learning · Computer Science 2018-01-15 Edward Choi , Siddharth Biswal , Bradley Malin , Jon Duke , Walter F. Stewart , Jimeng Sun

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Recent advances in generative modelling have led many to see synthetic data as the go-to solution for a range of problems around data access, scarcity, and under-representation. In this paper, we study three prominent use cases: (1) Sharing…

Machine Learning · Computer Science 2026-02-04 Bogdan Kulynych , Theresa Stadler , Jean Louis Raisaro , Carmela Troncoso

Healthcare research and development face significant obstacles due to data scarcity and stringent privacy regulations, such as HIPAA and the GDPR, restricting access to essential real-world medical data. These limitations impede innovation,…

Machine Learning · Computer Science 2025-10-17 Md Ibrahim Shikder Mahin , Md Shamsul Arefin , Md Tanvir Hasan

In Biomedical Natural Language Processing (BioNLP) tasks, such as Relation Extraction, Named Entity Recognition, and Text Classification, the scarcity of high-quality data remains a significant challenge. This limitation poisons large…

Computation and Language · Computer Science 2025-04-01 Zhengyi Zhao , Shubo Zhang , Bin Liang , Binyang Li , Kam-Fai Wong

Synthetic data is becoming increasingly integral in data-scarce fields such as medical imaging, serving as a substitute for real data. However, its inherent statistical characteristics can significantly impact downstream tasks, potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Krishan Agyakari Raja Babu , Rachana Sathish , Mrunal Pattanaik , Rahul Venkataramani

Generating synthetic data through generative models is gaining interest in the ML community and beyond. In the past, synthetic data was often regarded as a means to private data release, but a surge of recent papers explore how its…

Machine Learning · Computer Science 2023-04-10 Boris van Breugel , Mihaela van der Schaar

Machine learning practitioners frequently seek to leverage the most informative available data, without violating the data owner's privacy, when building predictive models. Differentially private data synthesis protects personal details…

Machine Learning · Computer Science 2020-11-12 Lucas Rosenblatt , Xiaoyan Liu , Samira Pouyanfar , Eduardo de Leon , Anuj Desai , Joshua Allen

Medical report generation aims to automatically produce radiology-style reports from medical images, supporting efficient and accurate clinical decision-making.However, existing approaches predominately rely on token-level likelihood…

Computation and Language · Computer Science 2026-03-30 Pengyu Wang , Shuchang Ye , Usman Naseem , Jinman Kim

Deep learning holds immense promise for aiding radiologists in breast cancer detection. However, achieving optimal model performance is hampered by limitations in availability and sharing of data commonly associated to patient privacy…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Richard Osuala , Daniel M. Lang , Anneliese Riess , Georgios Kaissis , Zuzanna Szafranowska , Grzegorz Skorupko , Oliver Diaz , Julia A. Schnabel , Karim Lekadir
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