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Retrieval-augmented generation (RAG) enhances the outputs of language models by integrating relevant information retrieved from external knowledge sources. However, when the retrieval process involves private data, RAG systems may face…

Cryptography and Security · Computer Science 2025-02-21 Shenglai Zeng , Jiankun Zhang , Pengfei He , Jie Ren , Tianqi Zheng , Hanqing Lu , Han Xu , Hui Liu , Yue Xing , Jiliang Tang

The development of robust clinical decision support systems is frequently impeded by the scarcity of high-fidelity, privacy-preserving biomedical data. While Generative Large Language Models (LLMs) offer a promising avenue for synthetic…

Machine Learning · Computer Science 2026-04-03 Arshia Ilaty , Hossein Shirazi , Amir Rahmani , Hajar Homayouni

Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…

Machine Learning · Computer Science 2022-08-25 Edmond Adib , Fatemeh Afghah , John J. Prevost

Offline reinforcement learning (RL) offers a promising framework for training agents using pre-collected datasets without the need for further environment interaction. However, policies trained on offline data often struggle to generalise…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Ahmet H. Güzel , Ilija Bogunovic , Jack Parker-Holder

This paper introduces SynDiffix, a mechanism for generating statistically accurate, anonymous synthetic data for structured data. Recent open source and commercial systems use Generative Adversarial Networks or Transformed Auto Encoders to…

Cryptography and Security · Computer Science 2023-11-17 Paul Francis , Cristian Berneanu , Edon Gashi

Synthetic data offers a promising solution to privacy concerns in healthcare by generating useful datasets in a privacy-aware manner. However, although synthetic data is typically developed with the intention of sharing said data, ambiguous…

Differentially private training algorithms like DP-SGD protect sensitive training data by ensuring that trained models do not reveal private information. An alternative approach, which this paper studies, is to use a sensitive dataset to…

Machine Learning · Computer Science 2024-01-12 Alexey Kurakin , Natalia Ponomareva , Umar Syed , Liam MacDermed , Andreas Terzis

Synthetic data generation is an appealing tool for augmenting and enriching datasets, playing a crucial role in advancing artificial intelligence (AI) and machine learning (ML). Not only does synthetic data help build robust AI/ML datasets…

Systems and Control · Electrical Eng. & Systems 2026-03-20 José Pulido , Francesc Wilhelmi , Sergio Fortes , Alfonso Fernández-Durán , Lorenzo Galati Giordano , Raquel Barco

In distributed computing environments, collaborative machine learning enables multiple clients to train a global model collaboratively. To preserve privacy in such settings, a common technique is to utilize frequent updates and…

Machine Learning · Computer Science 2025-01-24 Chia-Yuan Wu , Frank E. Curtis , Daniel P. Robinson

Research Agents enable models to gather information from the web using tools to answer user queries, requiring them to dynamically interleave internal reasoning with tool use. While such capabilities can in principle be learned via…

Artificial Intelligence · Computer Science 2026-03-10 Hansi Zeng , Zoey Li , Yifan Gao , Chenwei Zhang , Xiaoman Pan , Tao Yang , Fengran Mo , Jiacheng Lin , Xian Li , Jingbo Shang

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

LCRL is a software tool that implements model-free Reinforcement Learning (RL) algorithms over unknown Markov Decision Processes (MDPs), synthesising policies that satisfy a given linear temporal specification with maximal probability. LCRL…

Machine Learning · Computer Science 2022-09-22 Hosein Hasanbeig , Daniel Kroening , Alessandro Abate

Since clinical letters contain sensitive information, clinical-related datasets can not be widely applied in model training, medical research, and teaching. This work aims to generate reliable, various, and de-identified synthetic clinical…

Computation and Language · Computer Science 2024-09-17 Libo Ren , Samuel Belkadi , Lifeng Han , Warren Del-Pinto , Goran Nenadic

Recent reinforcement learning (RL) approaches have advanced radiology report generation (RRG), yet two core limitations persist: (1) report-level rewards offer limited evidence-grounded guidance for clinical faithfulness; and (2) current…

Machine Learning · Computer Science 2026-04-16 Qin Zhou , Guoyan Liang , Qianyi Yang , Jingyuan Chen , Sai Wu , Chang Yao , Zhe Wang

Cell tracking remains a pivotal yet challenging task in biomedical research. The full potential of deep learning for this purpose is often untapped due to the limited availability of comprehensive and varied training data sets. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Moritz Sturm , Lorenzo Cerrone , Fred A. Hamprecht

Federated learning has emerged as a paradigm for collaborative learning, enabling the development of robust models without the need to centralise sensitive data. However, conventional federated learning techniques have privacy and security…

Machine Learning · Computer Science 2024-07-31 Eugenio Lomurno , Matteo Matteucci

Nowadays, the use of synthetic data has gained popularity as a cost-efficient strategy for enhancing data augmentation for improving machine learning models performance as well as addressing concerns related to sensitive data privacy.…

Machine Learning · Computer Science 2025-10-27 Ioannis E. Livieris , Nikos Alimpertis , George Domalis , Dimitris Tsakalidis

Background: High-level system testing of applications that use data from e-Government services as input requires test data that is real-life-like but where the privacy of personal information is guaranteed. Applications with such strong…

Machine Learning · Computer Science 2026-02-09 Maj-Annika Tammisto , Faiz Ali Shah , Daniel Rodriguez , Dietmar Pfahl

LLM pretraining is shifting from a compute-bound to a data-bound regime, where available human (organic) text falls far short of scaling demands. However, reaching the data-bound regime does not mean the model has fully utilized its organic…

Computation and Language · Computer Science 2026-05-19 Zichun Yu , Chenyan Xiong
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