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Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Objective: This study aims to summarize the usage of Large Language Models (LLMs) in the process of creating a scientific review. We look at the range of stages in a review that can be automated and assess the current state-of-the-art…

Digital Libraries · Computer Science 2025-05-16 Dmitry Scherbakov , Nina Hubig , Vinita Jansari , Alexander Bakumenko , Leslie A. Lenert

Searching, filtering and analysing scientific literature are time-consuming tasks when performing a systematic literature review. With the rise of artificial intelligence, some steps in the review process are progressively being automated.…

Artificial Intelligence · Computer Science 2025-09-30 José de la Torre-López , Aurora Ramírez , José Raúl Romero

Understanding how and why large language models (LLMs) fail is becoming a central challenge as models rapidly evolve and static evaluations fall behind. While automated probing has been enabled by dynamic test generation, existing…

Computation and Language · Computer Science 2026-02-16 Yue Huang , Zhengzhe Jiang , Yuchen Ma , Yu Jiang , Xiangqi Wang , Yujun Zhou , Yuexing Hao , Kehan Guo , Pin-Yu Chen , Stefan Feuerriegel , Xiangliang Zhang

In response to the growing complexity and volume of scientific literature, this paper introduces the LLMs4Synthesis framework, designed to enhance the capabilities of Large Language Models (LLMs) in generating high-quality scientific…

Computation and Language · Computer Science 2024-09-30 Hamed Babaei Giglou , Jennifer D'Souza , Sören Auer

The emergence of Large Language Models (LLMs) has fundamentally transformed natural language processing, making them indispensable across domains ranging from conversational systems to scientific exploration. However, their pre-trained…

Literature research, vital for scientific work, faces the challenge of surging information volumes exceeding researchers' processing capabilities. We present an automated review generation method based on large language models (LLMs) to…

Computation and Language · Computer Science 2025-05-02 Shican Wu , Xiao Ma , Dehui Luo , Lulu Li , Xiangcheng Shi , Xin Chang , Xiaoyun Lin , Ran Luo , Chunlei Pei , Changying Du , Zhi-Jian Zhao , Jinlong Gong

Automated planning is concerned with developing efficient algorithms to generate plans or sequences of actions to achieve a specific goal in a given environment. Emerging Large Language Models (LLMs) can answer questions, write high-quality…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

As modern science becomes increasingly data-intensive, the ability to analyze and visualize large-scale, complex datasets is critical to accelerating discovery. However, many domain scientists lack the programming expertise required to…

Software Engineering · Computer Science 2025-12-01 Apu Kumar Chakroborti , Yi Ding , Lipeng Wan

The self-rationalising capabilities of LLMs are appealing because the generated explanations can give insights into the plausibility of the predictions. However, how faithful the explanations are to the predictions is questionable, raising…

Computation and Language · Computer Science 2024-12-18 Marc Braun , Jenny Kunz

Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Biomolecules · Quantitative Biology 2025-09-15 Long-Kai Huang , Rongyi Zhu , Bing He , Jianhua Yao

We introduce Probe Pruning (PP), a novel framework for online, dynamic, structured pruning of Large Language Models (LLMs) applied in a batch-wise manner. PP leverages the insight that not all samples and tokens contribute equally to the…

Computation and Language · Computer Science 2025-02-24 Qi Le , Enmao Diao , Ziyan Wang , Xinran Wang , Jie Ding , Li Yang , Ali Anwar

Language models have become increasingly powerful tools for formal mathematical reasoning. However, most existing approaches rely exclusively on either large general-purpose models or smaller specialized models, each with distinct…

Artificial Intelligence · Computer Science 2025-07-22 Nicolas Wischermann , Claudio Mayrink Verdun , Gabriel Poesia , Francesco Noseda

In recent years, large language models (LLMs) have demonstrated significant potential across various natural language processing (NLP) tasks. However, their performance in domain-specific applications and non-English languages remains less…

Computation and Language · Computer Science 2025-10-01 Dragos-Dumitru Ghinea , Adela-Nicoleta Corbeanu , Adrian-Marius Dumitran

The number of scientific articles published in the domain of food safety has consistently been increasing over the last few decades. It has therefore become unfeasible for food safety experts to read all relevant literature related to food…

Information Retrieval · Computer Science 2024-05-28 Neris Özen , Wenjuan Mu , Esther D. van Asselt , Leonieke M. van den Bulk

Large Language Models (LLMs) possess substantial reasoning capabilities and are increasingly applied to optimization tasks, particularly in synergy with evolutionary computation. However, while recent surveys have explored specific aspects…

Neural and Evolutionary Computing · Computer Science 2026-01-08 Yisong Zhang , Ran Cheng , Guoxing Yi , Kay Chen Tan

Unbiased, label-free proteomics is becoming a powerful technique for measuring protein expression in almost any biological sample. The output of these measurements after preprocessing is a collection of features and their associated…

Protein language models (pLMs) have recently gained significant attention for their ability to uncover relationships between sequence, structure, and function from evolutionary statistics, thereby accelerating therapeutic drug discovery.…

Machine Learning · Computer Science 2026-03-04 Darshan Patil , Pranshu Malviya , Mathieu Reymond , Quentin Fournier , Sarath Chandar

In this paper we demonstrate how logic programming systems and Automated first-order logic Theorem Provers (ATPs) can improve the accuracy of Large Language Models (LLMs) for logical reasoning tasks where the baseline performance is given…

Artificial Intelligence · Computer Science 2024-08-08 Lachlan McGinness , Peter Baumgartner