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In healthcare, applying deep learning models to electronic health records (EHRs) has drawn considerable attention. EHR data consist of a sequence of medical visits, i.e. a multivariate time series of diagnosis, medications, physical…

Machine Learning · Computer Science 2018-10-19 Jing Mei , Shiwan Zhao , Feng Jin , Eryu Xia , Haifeng Liu , Xiang Li

Medication recommendation systems have gained significant attention in healthcare as a means of providing tailored and effective drug combinations based on patients' clinical information. However, existing approaches often suffer from…

Machine Learning · Computer Science 2024-08-13 Zihao Zhao , Yi Jing , Fuli Feng , Jiancan Wu , Chongming Gao , Xiangnan He

The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have…

Machine Learning · Statistics 2019-08-20 Linying Zhang , Yixin Wang , Anna Ostropolets , Jami J. Mulgrave , David M. Blei , George Hripcsak

The problem of accelerating drug discovery relies heavily on automatic tools to optimize precursor molecules to afford them with better biochemical properties. Our work in this paper substantially extends prior state-of-the-art on…

Chemical Physics · Physics 2019-10-22 Wengong Jin , Regina Barzilay , Tommi Jaakkola

Hierarchical text classification (HTC) is essential for various real applications. However, HTC models are challenging to develop because they often require processing a large volume of documents and labels with hierarchical taxonomy.…

Computation and Language · Computer Science 2023-11-08 SangHun Im , Gibaeg Kim , Heung-Seon Oh , Seongung Jo , Donghwan Kim

Hierarchical text classification (HTC) is a special sub-task of multi-label classification (MLC) whose taxonomy is constructed as a tree and each sample is assigned with at least one path in the tree. Latest HTC models contain three…

Computation and Language · Computer Science 2024-08-13 Zhijian Chen , Zhonghua Li , Jianxin Yang , Ye Qi

This work presents Homomorphic Encryption Intermediate Representation (HEIR), a unified approach to building homomorphic encryption (HE) compilers. HEIR aims to support all mainstream techniques in homomorphic encryption, integrate with all…

Next point-of-interest (POI) recommendation is a critical task in location-based social networks, yet remains challenging due to a high degree of variation and personalization exhibited in user movements. In this work, we explore the latent…

Information Retrieval · Computer Science 2023-10-24 Jiayi Xie , Zhenzhong Chen

We propose a method to match anatomical locations between pairs of medical images in longitudinal comparisons. The matching is made possible by computing a descriptor of the query point in a source image based on a hierarchical sparse…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Halid Ziya Yerebakan , Yoshihisa Shinagawa , Mahesh Ranganath , Simon Allen-Raffl , Gerardo Hermosillo Valadez

Medical coding translates free-text clinical documentation into standardized codes drawn from classification systems that contain tens of thousands of entries and are updated annually. It is central to billing, clinical research, and…

Artificial Intelligence · Computer Science 2026-04-01 Joakim Edin , Andreas Motzfeldt , Simon Flachs , Lars Maaløe

How data is represented and operationalized is critical for building computational solutions that are both effective and efficient. A common approach is to represent data objects as binary vectors, denoted \textit{hash codes}, which require…

Information Retrieval · Computer Science 2021-09-07 Casper Hansen

A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…

Machine Learning · Computer Science 2020-05-19 Dehua Chen , Amir Jalilifard , Adriano Veloso , Nivio Ziviani

Hierarchical text classification is a challenging subtask of multi-label classification due to its complex label hierarchy. Existing methods encode text and label hierarchy separately and mix their representations for classification, where…

Computation and Language · Computer Science 2022-03-24 Zihan Wang , Peiyi Wang , Lianzhe Huang , Xin Sun , Houfeng Wang

Characterizing users' interests accurately plays a significant role in an effective recommender system. The sequential recommender system can learn powerful hidden representations of users from successive user-item interactions and dynamic…

Social and Information Networks · Computer Science 2020-11-24 Lingxiao Zhang , Jiangpeng Yan , Yujiu Yang , Xiu Li

We are interested in building collaborative filtering models for recommendation systems where users interact with slates instead of individual items. These slates can be hierarchical in nature. The central idea of our approach is to learn…

Information Retrieval · Computer Science 2020-10-15 Ehtsham Elahi , Ashok Chandrashekar

The growing demand for key healthcare resources such as clinical expertise and facilities has motivated the emergence of artificial intelligence (AI) based decision support systems. We address the problem of predicting clinical workups for…

Machine Learning · Computer Science 2020-07-24 Morteza Noshad , Ivana Jankovic , Jonathan H. Chen

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Retrosynthesis is essential for designing synthetic pathways for complex molecules and can be revolutionized by AI to automate and accelerate chemical synthesis planning for drug discovery and materials science. Here, we propose a…

Chemical Physics · Physics 2024-12-02 Seongeun Yun , Won Bo Lee

Existing Masked Image Modeling methods apply fixed mask patterns to guide the self-supervised training. As those mask patterns resort to different criteria to depict image contents, sticking to a fixed pattern leads to a limited vision cues…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Zhanzhou Feng , Shiliang Zhang

Objective: To transform heterogeneous clinical data from electronic health records into clinically meaningful constructed features using data driven method that rely, in part, on temporal relations among data. Materials and Methods: The…

Machine Learning · Computer Science 2017-06-22 Edward Choi , Andy Schuetz , Walter F. Stewart , Jimeng Sun
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