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Foundation models trained on patient electronic health records (EHRs) require tokenizing medical data into sequences of discrete vocabulary items. Existing tokenizers treat medical codes from EHRs as isolated textual tokens. However, each…

Computation and Language · Computer Science 2025-07-01 Xiaorui Su , Shvat Messica , Yepeng Huang , Ruth Johnson , Lukas Fesser , Shanghua Gao , Faryad Sahneh , Marinka Zitnik

In today's data-rich environment, recommender systems play a crucial role in decision support systems. They provide to users personalized recommendations and explanations about these recommendations. Embedding-based models, despite their…

Information Retrieval · Computer Science 2024-01-10 Ngoc Luyen Le , Marie-Hélène Abel , Philippe Gouspillou

Translating renderings (e. g. PDFs, scans) into hierarchical document structures is extensively demanded in the daily routines of many real-world applications. However, a holistic, principled approach to inferring the complete hierarchical…

Machine Learning · Computer Science 2021-01-26 Johannes Rausch , Octavio Martinez , Fabian Bissig , Ce Zhang , Stefan Feuerriegel

Medication recommendation is crucial in healthcare, offering effective treatments based on patient's electronic health records (EHR). Previous studies show that integrating more medication-related knowledge improves medication…

Artificial Intelligence · Computer Science 2025-04-28 Xiang Li , Haixu Ma , Guanyong Wu , Shi Mu , Chen Li , Shunpan Liang

Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Peixiang Huang , Yanyan Huang , Weiqin Zhao , Junjun He , Lequan Yu

This paper demonstrates a self-supervised framework for learning voxel-wise coarse-to-fine representations tailored for dense downstream tasks. Our approach stems from the observation that existing methods for hierarchical representation…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Eytan Kats , Jochen G. Hirsch , Mattias P. Heinrich

Drug recommendation (DR) systems aim to support healthcare professionals in selecting appropriate medications based on patients' medical conditions. State-of-the-art approaches utilize deep learning techniques for improving DR, but fall…

Information Retrieval · Computer Science 2025-11-03 Yu Lin , Zhen Jia , Philipp Christmann , Xu Zhang , Shengdong Du , Tianrui Li

The organization of latent token representations plays a crucial role in determining the stability, generalization, and contextual consistency of language models, yet conventional approaches to embedding refinement often rely on parameter…

Computation and Language · Computer Science 2025-03-26 Meiquan Dong , Haoran Liu , Yan Huang , Zixuan Feng , Jianhong Tang , Ruoxi Wang

Graph embedding is becoming an important method with applications in various areas, including social networks and knowledge graph completion. In particular, Poincar\'e embedding has been proposed to capture the hierarchical structure of…

Artificial Intelligence · Computer Science 2022-05-11 Daisuke Takehara , Kei Kobayashi

Recommender systems are designed to predict user preferences over collections of items. These systems process users' previous interactions to decide which items should be ranked higher to satisfy their desires. An ensemble recommender…

Information Retrieval · Computer Science 2023-06-23 Alireza Gharahighehi , Celine Vens , Konstantinos Pliakos

General perception systems such as Perceivers can process arbitrary modalities in any combination and are able to handle up to a few hundred thousand inputs. They achieve this generality by using exclusively global attention operations.…

Spatial Transcriptomics (ST) merges the benefits of pathology images and gene expression, linking molecular profiles with tissue structure to analyze spot-level function comprehensively. Predicting gene expression from histology images is a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Chen Zhang , Yilu An , Ying Chen , Hao Li , Xitong Ling , Lihao Liu , Junjun He , Yuxiang Lin , Zihui Wang , Rongshan Yu

Hyperdimensional computing (HD) is an emerging paradigm for machine learning based on the evidence that the brain computes on high-dimensional, distributed, representations of data. The main operation of HD is encoding, which transfers the…

Machine Learning · Computer Science 2020-07-22 Behnam Khaleghi , Sahand Salamat , Anthony Thomas , Fatemeh Asgarinejad , Yeseong Kim , Tajana Rosing

In this paper, we address the challenge of patient-note identification, which involves accurately matching an anonymized clinical note to its corresponding patient, represented by a set of related notes. This task has broad applications,…

Computation and Language · Computer Science 2025-04-01 Safa Alsaidi , Marc Vincent , Olivia Boyer , Nicolas Garcelon , Miguel Couceiro , Adrien Coulet

The integration of structured hierarchical embeddings into transformer-based architectures introduces a refined approach to lexical representation, ensuring that multi-scale semantic relationships are preserved without compromising…

With the development of natural language processing techniques(NLP), automatic diagnosis of eye diseases using ophthalmology electronic medical records (OEMR) has become possible. It aims to evaluate the condition of both eyes of a patient…

Computation and Language · Computer Science 2023-01-12 Xu Ye , Meng Xiao , Zhiyuan Ning , Weiwei Dai , Wenjuan Cui , Yi Du , Yuanchun Zhou

Background: Existing clinical prediction models often represent patient data using features that ignore the semantic relationships between clinical concepts. This study integrates domain-specific semantic information by mapping the SNOMED…

Machine Learning · Computer Science 2025-08-21 Luis H. John , Jan A. Kors , Jenna M. Reps , Peter R. Rijnbeek , Egill A. Fridgeirsson

With the rapid increase of compound databases available in medicinal and material science, there is a growing need for learning representations of molecules in a semi-supervised manner. In this paper, we propose an unsupervised hierarchical…

Machine Learning · Statistics 2017-11-30 Hai Nguyen , Shin-ichi Maeda , Kenta Oono

A new algorithm, "HiER-leap", is derived which improves on the computational properties of the ER-leap algorithm for exact accelerated simulation of stochastic chemical kinetics. Unlike ER-leap, HiER-leap utilizes a hierarchical or…

Molecular Networks · Quantitative Biology 2012-12-18 David Orendorff , Eric Mjolsness

We address the medication recommendation problem, which aims to recommend effective medications for a patient's current visit by utilizing information (e.g., diagnoses and procedures) given at the patient's current and past visits. While…

Information Retrieval · Computer Science 2023-12-20 Taeri Kim , Jiho Heo , Hongil Kim , Kijung Shin , Sang-Wook Kim