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Foundation models like the Segment Anything Model (SAM) excel in zero-shot segmentation for natural images but struggle with medical image segmentation due to differences in texture, contrast, and noise. Annotating medical images is costly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Sourya Sengupta , Satrajit Chakrabarty , Keerthi Sravan Ravi , Gopal Avinash , Ravi Soni

Fully convolutional neural networks (CNNs) have proven to be effective at representing and classifying textural information, thus transforming image intensity into output class masks that achieve semantic image segmentation. In medical…

Computer Vision and Pattern Recognition · Computer Science 2019-09-12 Ali Hatamizadeh , Demetri Terzopoulos , Andriy Myronenko

Segment Anything (SAM), an advanced universal image segmentation model trained on an expansive visual dataset, has set a new benchmark in image segmentation and computer vision. However, it faced challenges when it came to distinguishing…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Xiao Feng Zhang , Tian Yi Song , Jia Wei Yao

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

Segment Anything Model (SAM) has gained significant attention because of its ability to segment various objects in images given a prompt. The recently developed SAM 2 has extended this ability to video inputs. This opens an opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Haoyu Dong , Hanxue Gu , Yaqian Chen , Jichen Yang , Yuwen Chen , Maciej A. Mazurowski

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Yizhe Zhang , Shuo Wang , Tao Zhou , Qi Dou , Danny Z. Chen

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

Segmenting and recognizing diverse object parts is crucial in computer vision and robotics. Despite significant progress in object segmentation, part-level segmentation remains underexplored due to complex boundaries and scarce annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Xinjian Wu , Ruisong Zhang , Jie Qin , Shijie Ma , Cheng-Lin Liu

This study investigates the potential of eye-tracking technology and the Segment Anything Model (SAM) to design a collaborative human-computer interaction system that automates medical image segmentation. We present the \textbf{GazeSAM}…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Bin Wang , Armstrong Aboah , Zheyuan Zhang , Ulas Bagci

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

Although vision foundation models (VFMs) are increasingly reused for biomedical image analysis, it remains unclear whether the latent representations they provide are general enough to support effective transfer and reuse across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Caterina Fuster-Barceló , Virginie Uhlmann

Learning to segmentation without large-scale samples is an inherent capability of human. Recently, Segment Anything Model (SAM) performs the significant zero-shot image segmentation, attracting considerable attention from the computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Chuanfei Hu , Tianyi Xia , Shenghong Ju , Xinde Li

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…

The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Benjamin Towle , Xin Chen , Ke Zhou

The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

The Segment Anything Model (SAM) has set a new standard in interactive image segmentation, offering robust performance across various tasks. However, its significant computational requirements limit its deployment in real-time or…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Kunal Dasharath Patil , Gowthamaan Palani , Ganapathy Krishnamurthi

Electron microscopic connectomics is an ambitious research direction with the goal of studying comprehensive brain connectivity maps by using high-throughput, nano-scale microscopy. One of the main challenges in connectomics research is…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Tran Minh Quan , David G. C. Hildebrand , Won-Ki Jeong
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