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Medical coding converts free-text clinical notes into standardized diagnostic and procedural codes, which are essential for billing, hospital operations, and medical research. Unlike ordinary text classification, it requires multi-step…

Artificial Intelligence · Computer Science 2025-11-18 Jiyang Zheng , Islam Nassar , Thanh Vu , Xu Zhong , Yang Lin , Tongliang Liu , Long Duong , Yuan-Fang Li

Large language models (LLMs) have performed well across various clinical natural language processing tasks, despite not being directly trained on electronic health record (EHR) data. In this work, we examine how popular open-source LLMs…

Computation and Language · Computer Science 2025-05-26 Furong Jia , David Sontag , Monica Agrawal

Clinical notes are text documents that are created by clinicians for each patient encounter. They are typically accompanied by medical codes, which describe the diagnosis and treatment. Annotating these codes is labor intensive and error…

Computation and Language · Computer Science 2018-04-18 James Mullenbach , Sarah Wiegreffe , Jon Duke , Jimeng Sun , Jacob Eisenstein

Detecting Alzheimer's Disease (AD) from narrative transcripts remains a challenging task for large language models (LLMs), particularly under out-of-distribution (OOD) and data-scarce conditions. While in-context learning (ICL) provides a…

Computation and Language · Computer Science 2025-11-11 Puzhen Su , Yongzhu Miao , Chunxi Guo , Jintao Tang , Shasha Li , Ting Wang

Large language models (LLMs) have led to breakthroughs in language tasks, yet the internal mechanisms that enable their remarkable generalization and reasoning abilities remain opaque. This lack of transparency presents challenges such as…

Computation and Language · Computer Science 2024-04-17 Haiyan Zhao , Fan Yang , Bo Shen , Himabindu Lakkaraju , Mengnan Du

Abbreviations are unavoidable yet critical parts of the medical text. Using abbreviations, especially in clinical patient notes, can save time and space, protect sensitive information, and help avoid repetitions. However, most abbreviations…

Computation and Language · Computer Science 2022-10-07 Mucahit Cevik , Sanaz Mohammad Jafari , Mitchell Myers , Savas Yildirim

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

The impressive capabilities of large language models (LLMs) have attracted extensive interests of applying LLMs to medical field. However, the complex nature of clinical environments presents significant hallucination challenges for LLMs,…

Computation and Language · Computer Science 2024-10-22 Derong Xu , Ziheng Zhang , Zhihong Zhu , Zhenxi Lin , Qidong Liu , Xian Wu , Tong Xu , Xiangyu Zhao , Yefeng Zheng , Enhong Chen

Unsupervised pretraining is an integral part of many natural language processing systems, and transfer learning with language models has achieved remarkable results in many downstream tasks. In the clinical application of medical code…

Computation and Language · Computer Science 2022-06-03 Shaoxiong Ji , Matti Hölttä , Pekka Marttinen

While Transformer language models (LMs) are state-of-the-art for information extraction, long text introduces computational challenges requiring suboptimal preprocessing steps or alternative model architectures. Sparse attention LMs can…

Computation and Language · Computer Science 2022-12-01 Joel Stremmel , Brian L. Hill , Jeffrey Hertzberg , Jaime Murillo , Llewelyn Allotey , Eran Halperin

Automatic International Classification of Diseases (ICD) coding plays a crucial role in the extraction of relevant information from clinical notes for proper recording and billing. One of the most important directions for boosting the…

Machine Learning · Computer Science 2024-02-27 Junyu Luo , Xiaochen Wang , Jiaqi Wang , Aofei Chang , Yaqing Wang , Fenglong Ma

Pretrained transformer-based Language Models (LMs) are well-known for their ability to achieve significant improvement on NLP tasks, but their black-box nature, which leads to a lack of interpretability, has been a major concern. My…

Computation and Language · Computer Science 2024-12-06 Ximing Wen

The adoption of machine learning in high-stakes applications such as healthcare and law has lagged in part because predictions are not accompanied by explanations comprehensible to the domain user, who often holds the ultimate…

Large Language Models (LLMs) rely on various decoding strategies to generate text, and these choices can significantly affect output quality. In healthcare, where accuracy is critical, the impact of decoding strategies remains…

Computation and Language · Computer Science 2025-08-20 Oriana Presacan , Alireza Nik , Vajira Thambawita , Bogdan Ionescu , Michael Riegler

Understanding how Large Language Models (LLMs) process information from prompts remains a significant challenge. To shed light on this "black box," attention visualization techniques have been developed to capture neuron-level perceptions…

The vocabulary used by language models (LM) - defined by the tokenizer - plays a key role in text generation quality. However, its impact remains under-explored in radiology. In this work, we address this gap by systematically comparing…

Computation and Language · Computer Science 2025-08-14 Hermione Warr , Wentian Xu , Harry Anthony , Yasin Ibrahim , Daniel McGowan , Konstantinos Kamnitsas

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Mapping clinical documents to standardised clinical vocabularies is an important task, as it provides structured data for information retrieval and analysis, which is essential to clinical research, hospital administration and improving…

Computation and Language · Computer Science 2025-09-15 Mingyang Li , Viktor Schlegel , Tingting Mu , Warren Del-Pinto , Goran Nenadic

Automatic medical coding has the potential to ease documentation and billing processes. For this task, transparency plays an important role for medical coders and regulatory bodies, which can be achieved using explainability methods.…

Computation and Language · Computer Science 2025-07-03 Katharina Beckh , Elisa Studeny , Sujan Sai Gannamaneni , Dario Antweiler , Stefan Rüping

Machine learning models that offer excellent predictive performance often lack the interpretability necessary to support integrated human machine decision-making. In clinical medicine and other high-risk settings, domain experts may be…

Machine Learning · Computer Science 2021-04-19 Zach Wood-Doughty , Isabel Cachola , Mark Dredze