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Interpretability of deep neural networks (DNNs) is essential since it enables users to understand the overall strengths and weaknesses of the models, conveys an understanding of how the models will behave in the future, and how to diagnose…

Computer Vision and Pattern Recognition · Computer Science 2017-03-31 Yinpeng Dong , Hang Su , Jun Zhu , Bo Zhang

Convolutional neural network based systems have largely failed to be adopted in many high-risk application areas, including healthcare, military, security, transportation, finance, and legal, due to their highly uninterpretable "black-box"…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Rodney LaLonde , Drew Torigian , Ulas Bagci

In the present paper we present the potential of Explainable Artificial Intelligence methods for decision-support in medical image analysis scenarios. With three types of explainable methods applied to the same medical image data set our…

Artificial Intelligence · Computer Science 2021-05-20 Samanta Knapič , Avleen Malhi , Rohit Saluja , Kary Främling

Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

Vision Language Models (VLMs) encode multimodal inputs over large, complex, and difficult-to-interpret architectures, which limit transparency and trust. We propose a Multimodal Inversion for Model Interpretation and Conceptualization…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Animesh Jain , Alexandros Stergiou

The importance of explainability in machine learning continues to grow, as both neural-network architectures and the data they model become increasingly complex. Unique challenges arise when a model's input features become high dimensional:…

Machine Learning · Computer Science 2021-12-21 Damien de Mijolla , Christopher Frye , Markus Kunesch , John Mansir , Ilya Feige

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

Multi-view clustering has become a significant area of research, with numerous methods proposed over the past decades to enhance clustering accuracy. However, in many real-world applications, it is crucial to demonstrate a clear…

Machine Learning · Computer Science 2025-02-07 Mudi Jiang , Lianyu Hu , Zengyou He , Zhikui Chen

Automated ICD-10 coding from clinical discharge summaries requires models that are both accurate on long-tailed multi-label classification tasks and interpretable to clinicians. Concept Bottleneck Models (CBMs) offer a principled framework…

Machine Learning · Computer Science 2026-05-12 Mohammed Sameer Syed , Xuan Lu

Medical Visual Language Models have shown great potential in various healthcare applications, including medical image captioning and diagnostic assistance. However, most existing models rely on text-based instructions, limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Tan-Hanh Pham , Chris Ngo , Trong-Duong Bui , Minh Luu Quang , Tan-Huong Pham , Truong-Son Hy

Explainable AI is an emerging field providing solutions for acquiring insights into automated systems' rationale. It has been put on the AI map by suggesting ways to tackle key ethical and societal issues. Existing explanation techniques…

Machine Learning · Computer Science 2022-05-02 Ioannis Mollas , Nick Bassiliades , Grigorios Tsoumakas

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

An important line of research attempts to explain CNN image classifier predictions and intermediate layer representations in terms of human-understandable concepts. Previous work supports that deep representations are linearly separable…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Alexandros Doumanoglou , Stylianos Asteriadis , Dimitrios Zarpalas

Deep neural networks (DNNs) achieve remarkable predictive performance but remain difficult to interpret, largely due to overparameterization that obscures the minimal structure required for interpretation. Here we introduce DeepIn, a…

Methodology · Statistics 2026-03-26 Zhiyao Tan , Liu Li , Huazhen Lin

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Deep neural networks exhibit remarkable performance, yet their black-box nature limits their utility in fields like healthcare where interpretability is crucial. Existing explainability approaches often sacrifice accuracy and lack…

Machine Learning · Computer Science 2025-04-08 Linhui Huang , Sayeri Lala , Niraj K. Jha

The scarcity of annotated data has sparked significant interest in unsupervised pre-training methods that leverage medical reports as auxiliary signals for medical visual representation learning. However, existing research overlooks the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Zhe Li , Laurence T. Yang , Bocheng Ren , Xin Nie , Zhangyang Gao , Cheng Tan , Stan Z. Li
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