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Access to real-world healthcare data is limited by stringent privacy regulations and data imbalances, hindering advancements in research and clinical applications. Synthetic data presents a promising solution, yet existing methods often…

Machine Learning · Computer Science 2025-03-11 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

The vast amount of available medical records has the potential to improve healthcare and biomedical research. However, privacy restrictions make these data accessible for internal use only. Recent works have addressed this problem by…

Computation and Language · Computer Science 2025-01-31 Samuel Belkadi , Libo Ren , Nicolo Micheletti , Lifeng Han , Goran Nenadic

In this paper, our goal is to generate synthetic data for heterogeneous (mixed-type) tabular datasets with high machine learning utility (MLu). Since the MLu performance depends on accurately approximating the conditional distributions, we…

Machine Learning · Computer Science 2024-08-20 Seunghwan An , Gyeongdong Woo , Jaesung Lim , ChangHyun Kim , Sungchul Hong , Jong-June Jeon

Recent studies on deepfake detection have achieved promising results when training and testing faces are from the same dataset. However, their results severely degrade when confronted with forged samples that the model has not yet seen…

Computer Vision and Pattern Recognition · Computer Science 2024-02-02 Tiewen Chen , Shanmin Yang , Shu Hu , Zhenghan Fang , Ying Fu , Xi Wu , Xin Wang

As a pragmatic data augmentation tool, data synthesis has generally returned dividends in performance for deep learning based medical image analysis. However, generating corresponding segmentation masks for synthetic medical images is…

Image and Video Processing · Electrical Eng. & Systems 2023-03-23 Xiaodan Xing , Giorgos Papanastasiou , Simon Walsh , Guang Yang

Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

Machine Learning · Computer Science 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Access to real clinical data is heavily restricted by privacy regulations, hindering both healthcare research and education. These constraints slow progress in developing new treatments and data-driven healthcare solutions, while also…

Machine Learning · Computer Science 2024-10-23 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

Enhancing reproducibility and data accessibility is essential to scientific research. However, ensuring data privacy while achieving these goals is challenging, especially in the medical field, where sensitive data are often commonplace.…

Methodology · Statistics 2025-09-24 Marta Cipriani , Lorenzo Di Rocco , Maria Puopolo , Marco Alfò

Semi-supervised learning is of great significance in medical image segmentation by exploiting unlabeled data. Among its strategies, the co-training framework is prominent. However, previous co-training studies predominantly concentrate on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Pengcheng Zhou , Lantian Zhang , Wei Li

Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Ishan Kumarasinghe , Dasuni Kawya , Madhura Edirisooriya , Isuri Devindi , Isuru Nawinne , Vajira Thambawita

Datasets in engineering domains are often small, sparsely labeled, and contain numerical as well as categorical conditions. Additionally. computational resources are typically limited in practical applications which hinders the adoption of…

Machine Learning · Computer Science 2025-05-23 Phillip Mueller , Jannik Wiese , Sebastian Mueller , Lars Mikelsons

Data augmentation is a widely used strategy to improve model robustness and generalization by enriching training datasets with synthetic examples. While large language models (LLMs) have demonstrated strong generative capabilities for this…

Machine Learning · Computer Science 2025-09-29 Dongkyu Cho , Miao Zhang , Rumi Chunara

Psychiatric symptom identification on social media aims to infer fine-grained mental health symptoms from user-generated posts, allowing a detailed understanding of users' mental states. However, the construction of large-scale…

Computation and Language · Computer Science 2026-03-24 Migyeong Kang , Jihyun Kim , Hyolim Jeon , Sunwoo Hwang , Jihyun An , Yonghoon Kim , Haewoon Kwak , Jisun An , Jinyoung Han

Marginal structural models (MSMs) are often used to estimate causal effects of treatments on survival time outcomes from observational data when time-dependent confounding may be present. They can be fitted using, e.g., inverse probability…

Methodology · Statistics 2023-12-27 Shaun R Seaman , Ruth H Keogh

Counterfactuals, serving as one of the emerging type of model interpretations, have recently received attention from both researchers and practitioners. Counterfactual explanations formalize the exploration of ``what-if'' scenarios, and are…

Machine Learning · Computer Science 2021-06-17 Fan Yang , Sahan Suresh Alva , Jiahao Chen , Xia Hu

$\textbf{Background:}$ At the onset of a pandemic, such as COVID-19, data with proper labeling/attributes corresponding to the new disease might be unavailable or sparse. Machine Learning (ML) models trained with the available data, which…

Since clinical letters contain sensitive information, clinical-related datasets can not be widely applied in model training, medical research, and teaching. This work aims to generate reliable, various, and de-identified synthetic clinical…

Computation and Language · Computer Science 2024-09-17 Libo Ren , Samuel Belkadi , Lifeng Han , Warren Del-Pinto , Goran Nenadic

Observational longitudinal data on treatments and covariates are increasingly used to investigate treatment effects, but are often subject to time-dependent confounding. Marginal structural models (MSMs), estimated using inverse probability…

Methodology · Statistics 2020-02-11 Ruth H. Keogh , Shaun R. Seaman , Jon Michael Gran , Stijn Vansteelandt

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das
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