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While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Computation and Language · Computer Science 2024-09-04 Daniil Filienko , Yinzhou Wang , Caroline El Jazmi , Serena Xie , Trevor Cohen , Martine De Cock , Weichao Yuwen

Depression has impacted millions of people worldwide and has become one of the most prevalent mental disorders. Early mental disorder detection can lead to cost savings for public health agencies and avoid the onset of other major…

Computation and Language · Computer Science 2025-01-03 Giuliano Lorenzoni , Pedro Elkind Velmovitsky , Paulo Alencar , Donald Cowan

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come…

Computation and Language · Computer Science 2024-08-02 Hannah R. Lawrence , Renee A. Schneider , Susan B. Rubin , Maja J. Mataric , Daniel J. McDuff , Megan Jones Bell

Advancements in deep learning have generated a large-scale interest in the development of foundational deep learning models. The development of Large Language Models (LLM) has evolved as a transformative paradigm in conversational tasks,…

Computation and Language · Computer Science 2024-08-01 Nikil Sharan Prabahar Balasubramanian , Sagnik Dakshit

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

This paper introduces a novel paradigm for depression detection and treatment using advanced Large Language Models (LLMs): Generative Pre-trained Transformer 4 (GPT-4), Llama 2 chat, and Gemini. These LLMs are fine-tuned with specialized…

Computation and Language · Computer Science 2024-02-09 Aryan Agrawal

Depression is a prevalent mental health disorder that is difficult to detect early due to subjective symptom assessments. Recent advancements in large language models have offered efficient and cost-effective approaches for this objective.…

Computation and Language · Computer Science 2025-04-08 Longdi Xian , Jianzhang Ni , Mingzhu Wang

Mental health in children and adolescents has been steadily deteriorating over the past few years. The recent advent of Large Language Models (LLMs) offers much hope for cost and time efficient scaling of monitoring and intervention, yet…

Computation and Language · Computer Science 2024-04-29 Isabelle Lorge , Dan W. Joyce , Andrey Kormilitzin

Large Language Models (LLMs) are transforming mental health care by enhancing accessibility, personalization, and efficiency in therapeutic interventions. These AI-driven tools empower mental health professionals with real-time support,…

Computers and Society · Computer Science 2025-01-22 Hari Mohan Pandey

Large language models (LLMs) have demonstrated impressive performance across various domains. However, for clinical diagnosis, higher expectations are required for LLM's reliability and sensitivity: thinking like physicians and remaining…

Computation and Language · Computer Science 2025-04-21 Chenwei Yan , Xiangling Fu , Yuxuan Xiong , Tianyi Wang , Siu Cheung Hui , Ji Wu , Xien Liu

Users of social platforms often perceive these sites as supportive spaces to post about their mental health issues. Those conversations contain important traces about individuals' health risks. Recently, researchers have exploited this…

Computation and Language · Computer Science 2024-08-21 Eliseo Bao , Anxo Pérez , Javier Parapar

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Social media has become an important source for understanding mental health, providing researchers with a way to detect conditions like depression from user-generated posts. This tutorial provides practical guidance to address common…

Computation and Language · Computer Science 2025-08-06 Yeyubei Zhang , Zhongyan Wang , Zhanyi Ding , Yexin Tian , Jianglai Dai , Xiaorui Shen , Yunchong Liu , Yuchen Cao

Social telehealth has revolutionized healthcare by enabling patients to share symptoms and receive medical consultations remotely. Users frequently post symptoms on social media and online health platforms, generating a vast repository of…

Computation and Language · Computer Science 2025-02-04 Malak Mohamed , Rokaia Emad , Ali Hamdi

This study presents a systematic comparison of three approaches for the analysis of mental health text using large language models (LLMs): prompt engineering, retrieval augmented generation (RAG), and fine-tuning. Using LLaMA 3, we evaluate…

Computation and Language · Computer Science 2025-04-01 Arshia Kermani , Veronica Perez-Rosas , Vangelis Metsis

The global increase in mental illness requires innovative detection methods for early intervention. Social media provides a valuable platform to identify mental illness through user-generated content. This systematic review examines machine…

Machine Learning · Computer Science 2025-02-18 Yuchen Cao , Jianglai Dai , Zhongyan Wang , Yeyubei Zhang , Xiaorui Shen , Yunchong Liu , Yexin Tian

Should a large language model (LLM) be used as a therapist? In this paper, we investigate the use of LLMs to *replace* mental health providers, a use case promoted in the tech startup and research space. We conduct a mapping review of…

Computation and Language · Computer Science 2025-04-28 Jared Moore , Declan Grabb , William Agnew , Kevin Klyman , Stevie Chancellor , Desmond C. Ong , Nick Haber

Large Language Models (LLMs) have demonstrated exceptional natural language understanding abilities and have excelled in a variety of natural language processing (NLP)tasks in recent years. Despite the fact that most LLMs are trained…

Computation and Language · Computer Science 2023-10-25 Xiang Zhang , Senyu Li , Bradley Hauer , Ning Shi , Grzegorz Kondrak